Results 51 to 60 of about 188,891 (256)
Reconstructing enzyme evolution by protein engineering
FEBS Letters, EarlyView.Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler +2 more
wiley +1 more source
Complete convergence for B-valued Lp-mixingale sequences
International Journal of Mathematics and Mathematical Sciences, 1998 Under weaker conditions of probability,we discuss in this paper the complete convergence for the partial sums and the randomly indexed partial sums of B-valued Lp-mixingale sequences.
Liang Hanying, Ren Yaofeng
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Complete Convergence for END Random Variables under Sublinear Expectations
Discrete Dynamics in Nature and Society, 2021 In this paper, the complete convergence theorems of partial sums and weighted sums for extended negatively dependent random variables in sublinear expectation spaces have been studied and established.
Qunying Wu
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Journal of inequalities and applications, 2018 Let r≥1 , 1≤p0 with 1/α+1/β=1/p . Let {ank,1≤k≤n,n≥1} be an array of constants satisfying supn≥1n-1∑k=1n|ank|αεn1/p}0. We also provide moment conditions under which ∑n=1∞nr-2-q/pE(max1≤m≤n|∑k=1mankXk|-εn1/p)+q0, where q>0 . Our results improve and generalize those of Sung (Discrete Dyn. Nat. Soc. 2010:630608, 2010) and Wu et al. (Stat. Probab.
Pingyan Chen, Soo Hak Sung
openaire +4 more sources
FEBS Letters, EarlyView.The mycobacterial CIII‐CIV respiratory supercomplex is an obligate assembly, encompassing several subunits of unknown functions. We have characterized the intracellular subunit AscF, and show that it is unlikely to be a sensor for metals or nucleotides, but is required for growth on nonfermentable energy sources, and likely works as an adapter for ...
Eni Rile +8 more
wiley +1 more source
On complete convergence in a Banach space
International Journal of Mathematics and Mathematical Sciences, 1994 Sufficient conditions are given under which a sequence of independent random elements taking values in a Banach space satisfy the Hsu and Robbins law of large numbers. The complete convergence of random indexed sums of random elements is also considered.
Anna Kuczmaszewska, Dominik Szynal
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Structure‐forward targeting of claudins with synthetic binders
FEBS Letters, EarlyView.Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley +1 more source
On The Complete Convergence Of Randomly Weighted Sums Of Random Fields
Demonstratio Mathematica, 2014 Let {Xn̲, n̲ ∊ V ⊆ℕd } be a d-dimensional random field indexed by some subset V of lattice ℕd, which are stochastically dominated by a random variable X.
Gdula Agnieszka M., Krajka Andrzej
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Molecular Oncology, EarlyView.Dimethyl fumarate (DMF) reduces growth of HPV‐positive cervical cancer spheroids and induces ferroptosis in cervical cancer cells via blocking SLC7A11/Glutathione (GSH) axis. Combination of subcytotoxic doses of DMF and cisplatin (CDDP) further suppresses spheroid growth and drives cell death in 2D culture models.
Carolina Punziano +6 more
wiley +1 more source
Molecular Oncology, EarlyView.In the present work, we have identified a transcriptional signature based on the differential expression of six genes (BCL2&MAST4, HSH2D&LAT2, METRN&PITPNM2) that would facilitate the early detection of T‐cell acute lymphoblastic leukemia (T‐ALL) patients prone to a poor treatment response and could be implemented at diagnosis, along with other risk ...
Antonio Lahera +11 more
wiley +1 more source