Results 111 to 120 of about 423,962 (267)

A yeast model of 5‐oxoproline accumulation reveals a general toleration to 5‐oxoproline

open access: yesFEBS Open Bio, EarlyView.
Using a yeast model, we show that even high accumulation of 5‐oxoproline causes only mild cellular stress and does not trigger oxidative stress. Instead, cells adapt by activating efflux pumps and diverse protective pathways, suggesting that previously proposed harmful effects of 5‐oxoproline may arise from indirect metabolic imbalances rather than the
Pratiksha Dubey   +4 more
wiley   +1 more source

A special case of the tree packing conjecture

open access: yesElectronic Journal of Graph Theory and Applications
The Tree Packing Conjecture of Gyárfás states that for any set of n-1 trees T = {T₁, T₂, …, Tn-1}, where Ti has i edges, T can be packed into Kn. We define a family of trees called two-spiders that are almost stars, and show that packings of Kn with two ...
Marcus E Gubanyi
doaj   +1 more source

Time‐restricted feeding prior to Mycobacterium tuberculosis infection reduces tissue CD4+ T cells with limited impact on bacterial clearance

open access: yesFEBS Open Bio, EarlyView.
Time‐restricted feeding (TRF) in mice increased liver fatty acid oxidation and decreased fatty acid biosynthesis. These alterations persisted when TRF was discontinued and the host was infected with Mycobacterium tuberculosis. Pre‐exposure to TRF did not alter tissue (lung and spleen) mycobacterial burden but significantly reduced CD3+ T cells in lungs
Ashish Gupta   +7 more
wiley   +1 more source

Determining the b-chromatic number of subdivision-vertex neighbourhood coronas

open access: yesAnalele Stiintifice ale Universitatii Ovidius Constanta: Seria Matematica
Let G and H be two graphs, each one of them being a path, a cycle or a star. In this paper, we determine the b-chromatic number of every subdivision-vertex neighbourhood corona G ⊡ H or G ⊡ Kn, where Kn is the complete graph of order n.
Falcón Raúl M.   +2 more
doaj   +1 more source

Decompositions of the λ-Fold Complete Mixed Graph into Mixed 6-Stars

open access: yesAppliedMath
Graph and digraph decompositions are a fundamental part of design theory. Probably the best known decompositions are related to decomposing the complete graph into 3-cycles (which correspond to Steiner triple systems), and decomposing the complete ...
Robert Gardner, Kazeem Kosebinu
doaj   +1 more source

From energy provision to protein synthesis: Tunnelling nanotubes as mediators of intercellular metabolic cooperation in cancer

open access: yesFEBS Open Bio, EarlyView.
The cytoskeleton‐mediated transport of mitochondria via tunnelling nanotubes restores respiration, increases ATP production, rescues cells from apoptosis, activates the AKT/mTOR signalling pathway, promotes cell migration and invasiveness, contributes to cancer progression and treatment resistance.
Stanislava Martínková, Jan Trnka
wiley   +1 more source

Treatment with KCL‐286, a first‐in‐class retinoic acid receptor‐β (RARβ) agonist, ameliorates neuronal DNA damage and inflammation in a mouse model of Alzheimer's disease

open access: yesFEBS Open Bio, EarlyView.
Repair of neuronal DNA damage in Alzheimer's disease by KCL‐286. (A) Amyloid‐β oligomers and plaques impair neuronal DNA repair pathways, leading to DNA double‐strand breaks and glial activation. (B) KCL‐286 activates RARβ/RXR signalling via retinoic acid response elements (RAREs), associated with increased BRCA1 expression, enhanced DNA repair and ...
Natasha Hill   +6 more
wiley   +1 more source

A Ramsey-Theory-Based Approach to the Dynamics of Systems of Material Points

open access: yesDynamics
We propose a Ramsey-theory-based approach for the analysis of the behavior of isolated mechanical systems containing interacting particles. The total momentum of the system in the frame of the center of masses is zero.
Edward Bormashenko, Nir Shvalb
doaj   +1 more source

MagmaFlow: A desktop platform for artificial intelligence‐driven expression analysis

open access: yesFEBS Open Bio, EarlyView.
MagmaFlow is a free, no‐code platform for gene expression analysis. It generates interactive volcano plots, links genes to literature, pathways, and diseases, prioritizes candidates using millions of publications, identifies affected biological processes, builds network diagrams, and exports publication‐ready figures and reports for macOS and Windows ...
Carlos E. Buss   +7 more
wiley   +1 more source

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