Results 61 to 70 of about 1,691,893 (274)

PARP inhibition and pharmacological ascorbate demonstrate synergy in castration‐resistant prostate cancer

open access: yesMolecular Oncology, EarlyView.
Pharmacologic ascorbate (vitamin C) increases ROS, disrupts cellular metabolism, and induces DNA damage in CRPC cells. These effects sensitize tumors to PARP inhibition, producing synergistic growth suppression with olaparib in vitro and significantly delayed tumor progression in vivo. Pyruvate rescue confirms ROS‐dependent activity.
Nicolas Gordon   +13 more
wiley   +1 more source

Decompositions of complete graphs and complete bipartite graphs into isomorphic supersubdivision graphs

open access: yesDiscrete Mathematics, 2003
zbMATH Open Web Interface contents unavailable due to conflicting licenses.
Sethuraman, G., Selvaraju, P.
openaire   +2 more sources

LDAcoop: Integrating non‐linear population dynamics into the analysis of clonogenic growth in vitro

open access: yesMolecular Oncology, EarlyView.
Limiting dilution assays (LDAs) quantify clonogenic growth by seeding serial dilutions of cells and scoring wells for colony formation. The fraction of negative wells is plotted against cells seeded and analyzed using the non‐linear modeling of LDAcoop.
Nikko Brix   +13 more
wiley   +1 more source

Complete edge-colored permutation graphs

open access: yesAdvances in Applied Mathematics, 2022
Nous introduisons le concept de graphes de permutation complets de couleur d'arête comme des graphes complets qui sont l'union bord-disjonction de graphes de permutation « classiques ». Nous montrons qu'un graphe G=(V,E) est un graphe de permutation complet de couleur de bord si et seulement si chaque sous-graphe monochromatique de G est un graphe de ...
Tom Hartmann   +5 more
openaire   +5 more sources

Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin

open access: yesMolecular Oncology, EarlyView.
The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla   +10 more
wiley   +1 more source

A note on the metric dimension of subdivided thorn graphs

open access: yesIndonesian Journal of Combinatorics, 2019
For some ordered subset W = {w1, w2, ⋯, wt} of vertices in connected graph G, and for some vertex v in G, the metric representation of v with respect to W is defined as the t-vector r(v∣W) = {d(v, w1), d(v, w2), ⋯, d(v, wt)}.
Lyra Yulianti   +2 more
doaj   +1 more source

Infrared laser sampling of low volumes combined with shotgun lipidomics reveals lipid markers in palatine tonsil carcinoma

open access: yesMolecular Oncology, EarlyView.
Nanosecond infrared laser (NIRL) low‐volume sampling combined with shotgun lipidomics uncovers distinct lipidome alterations in oropharyngeal squamous cell carcinoma (OPSCC) of the palatine tonsil. Several lipid species consistently differentiate tumor from healthy tissue, highlighting their potential as diagnostic markers.
Leonard Kerkhoff   +11 more
wiley   +1 more source

A note on star coloring of central graph of bipartite graph and corona graph of complete graph with path and cycle [PDF]

open access: yesTransactions on Combinatorics, 2012
In this paper, we find the star chromatic number of central graph of complete bipartite graph and corona graph of complete graph with path and cycle.
V. J. Vernold, M. Venkatachalam
doaj  

Total Edge Irregularity Strength of Complete Graphs and Complete Bipartite Graphs

open access: yesElectronic Notes in Discrete Mathematics, 2007
zbMATH Open Web Interface contents unavailable due to conflicting licenses.
Jendrol’, Stanislav   +2 more
openaire   +2 more sources

TRAIL‐PEG‐Apt‐PLGA nanosystem as an aptamer‐targeted drug delivery system potential for triple‐negative breast cancer therapy using in vivo mouse model

open access: yesMolecular Oncology, EarlyView.
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat   +8 more
wiley   +1 more source

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