Results 61 to 70 of about 423,962 (267)

Decomposing the Complete Graph Into Hamiltonian Paths (Cycles) and 3-Stars

Discussiones Mathematicae Graph Theory, 2020
Let H be a graph. A decomposition of H is a set of edge-disjoint subgraphs of H whose union is H. A Hamiltonian path (respectively, cycle) of H is a path (respectively, cycle) that contains every vertex of H exactly once.
Lee Hung-Chih, Chen Zhen-Chun
doaj   +1 more source

The role of miR‐335‐5p in the redifferentiation of BRAF p.V600E thyroid cancers

Molecular Oncology, EarlyView.
The BRAF p.V600E mutation promotes thyroid cancer dedifferentiation and radioiodine resistance. Using a network approach, we identified miR‐335‐5p as a key regulator of BRAF‐mutated thyroid tumors. Restoring miR‐335‐5p increased thyroid‐specific gene expression and iodine uptake in cells and organoids.
Valeria Pecce, Simone Bini, Marialuisa Sponziello, Giorgio Grani, Giulia Fiscon, Paola Paci, Lorenzo Farina, Rosa Falcone, Valentina Maggisano, Sebastiano Filetti, Cosimo Durante, Antonella Verrienti   +11 more
wiley   +1 more source

Enumeration of Matchings in the Incidence Graphs of Complete and Complete Bipartite Graphs

SIAM Journal on Discrete Mathematics, 2002
Summary: If \(G=(V,E)\) is a graph, the incidence graph \(I(G)\) is the graph with vertices \(V\cup E\) and an edge joining \(v\in V\) and \(e\in E\) when and only when \(v\) is incident with \(e\) in \(G\). For \(G\) equal to \(K_{n}\) (the complete graph on \(n\) vertices) or \(K_{n,n}\) (the complete bipartite graph on \(n + n\) vertices), we ...
openaire   +2 more sources

Establishment of a humanized patient‐derived xenograft mouse model of high‐grade serous ovarian cancer for preclinical evaluation of combination immunotherapy

Molecular Oncology, EarlyView.
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric, Line Bjørge, Martine Rott Lode, Cecilie Fredvik Torkildsen, Pia Aehnlich, Rammah Elnour, Daniela Elena Costea, Lars Andreas Akslen, Liv Cecilie Vestrheim Thomsen, Emmet McCormack, Katrin Kleinmanns   +10 more
wiley   +1 more source

Differential expression of cancer‐related genes supports prediction of poor response to first‐line treatments in T‐ALL pediatric patients with high minimal residual disease

Molecular Oncology, EarlyView.
In the present work, we have identified a transcriptional signature based on the differential expression of six genes (BCL2&MAST4, HSH2D&LAT2, METRN&PITPNM2) that would facilitate the early detection of T‐cell acute lymphoblastic leukemia (T‐ALL) patients prone to a poor treatment response and could be implemented at diagnosis, along with other risk ...
Antonio Lahera, Laura Vela‐Martín, Pablo Fernández‐Navarro, José Luis López‐Lorenzo, Javier Cornago, Pilar Llamas, Eduardo Pérez‐Gómez, José Luis Marín‐Rubio, Manuel Fresno, Javier Santos, José Fernández‐Piqueras, María Villa‐Morales   +11 more
wiley   +1 more source

CCDC80 suppresses high‐grade serous ovarian cancer migration via negative regulation of B7‐H3

Molecular Oncology, EarlyView.
PAX8 is a lineage‐specific master regulator of transcription in high‐grade serous ovarian cancer (HGSC) progression. We show for the first time that PAX8 facilitates proliferation and metastasis by repressing the cell autonomous tumor suppressor CCDC80 and inducing B7‐H3 expression.
Aya Saleh, Nitzan Medina‐Itzhaki, Milena Chekov, Eden Gal‐Swisa, Roba Gabesh‐Wahabi, Inbar Savyon, Inna Naroditsky, Hilary A. Kenny, Basem Fares, Lina Korsensky, Einav Girsh, Liron Berger, Ruth Perets   +12 more
wiley   +1 more source

Simulations for the Susceptible-Exposed-Infected-Recovered (SEIR) Model in the Forecast of Epidemic Outbreak

Journal of Engineering Technology and Applied Physics
Mathematical modelling based on the compartmental Susceptible – Exposed – Infected - Recovered (SEIR) model is proposed in this paper to study the pandemic outbreak.
Mei Feng Liu, Boo Hui Ling
doaj   +1 more source

Characterization of Graphs Associated with Numerical Semigroups

Mathematics, 2019
Let Γ be a numerical semigroup. We associate an undirected graph G ( Γ ) with a numerical semigroup Γ with vertex set { v i : i ∈ N \ Γ } and edge set { v i v j ⇔ i + j ∈ Γ }
Muhammad Ahsan Binyamin, Hafiz Muhammad Afzal Siddiqui, Nida Munawar Khan, Adnan Aslam, Yongsheng Rao   +4 more
doaj   +1 more source

KDM7A and KDM1A inhibition suppresses tumour promoting pathways in prostate cancer

Molecular Oncology, EarlyView.
Treatment resistance is a major challenge for patients with advanced prostate cancer. This study examined an alternative approach to target the major prostate cancer‐promoting pathway by targeting epigenetic factors, whose levels are higher in tumours.
Jennie N Jeyapalan, Veronika M Metzler, Simone de Brot, Corinne L Woodcock, Anna E Harris, Jennifer Lothion‐Roy, Emeli M Nilsson, Atara Ntekim, Michael S Toss, Jenny L Persson, Francesca Khani, Brian D Robinson, Lorraine J Gudas, Emad Rakha, David M Heery, Catrin S Rutland, Nigel P Mongan   +16 more
wiley   +1 more source

Dimensi Metrik Kuat Lokal Graf Hasil Operasi Kali Kartesian

Contemporary Mathematics and Applications (ConMathA), 2020
The strong local metric dimension is the development result of a strong metric dimension study, one of the study topics in graph theory. Some of graphs that have been discovered about strong local metric dimension are path graph, star graph, complete ...
Nurma Ariska Sutardji, Liliek Susilowati, Utami Dyah Purwati   +2 more
doaj   +1 more source