Results 81 to 90 of about 423,962 (267)

A Novel Approach for Neutrosophic Complete Graph and Neutrosophic Excellent Domination [PDF]

open access: yesNeutrosophic Sets and Systems
Social networks have a crucial role in forming contemporary society. The way they operate and reach allow them to have a large-scale impact on beliefs, behaviours, and trust.
Murugan Raji   +3 more
doaj   +1 more source

MITF maintains genome stability in nonmelanocyte lineages

open access: yesMolecular Oncology, EarlyView.
MITF is essential for melanocyte survival and acts as an oncogene in 10%–20% of melanomas. We show that MITF depletion causes genome instability in nonmelanocytic cells, leading to LATS2‐mediated P53 activation, cell cycle arrest, and apoptosis. This study highlights the role of MITF as a genome maintenance factor beyond the melanocyte lineage. Created
Drifa H. Gudmundsdottir   +13 more
wiley   +1 more source

A novel quinazolinone insulin receptor inhibitor and its synergy with an EGFR inhibitor in glucose‐driven glioblastoma

open access: yesMolecular Oncology, EarlyView.
The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka   +9 more
wiley   +1 more source

Effects on Seidel energy of two special types of graphs by perturbing edges

open access: yesKuwait Journal of Science
Let G be a simple undirected graph, and let S(G) be its Seidel matrix. The Seidel energy of G is defined as ES(G)=∑i=1n|λS(G)|, where λS(G),λS(G),…,λS(G) are Seidel eigenvalues of G.
doaj   +1 more source

Oncogenic DMTF1β promotes cancer cell motility by regulating autophagy through ULK1 stabilization

open access: yesMolecular Oncology, EarlyView.
In the current study, we demonstrate that the oncogene DMTF1β regulates ULK1 stability by reducing its proteasomal degradation in cancer cells. This stabilization enables ULK1 to induce autophagy, which in turn facilitates cancer cell migration. Consequently, reduced DMTF1β levels lead to decreased autophagy and impaired cancer cell migration.
Jun Xu   +13 more
wiley   +1 more source

Green's graphs of a semigroup

open access: yesOpen Mathematics
Let SS be a semigroup. In this study, we first introduce the Green’s digraphs and Green’s graphs related to the Green’s relations L{\mathscr{L}}, R{\mathscr{R}}, and J{\mathscr{J}} of SS.
Cheng Yanliang, Shao Yong, Ma Xuanlong
doaj   +1 more source

Some Properties of the Nil-Graphs of Ideals of Commutative Rings

open access: yesپژوهش‌های ریاضی, 2022
Let R be a commutative ring with identity and Nil(R) be the set of nilpotent elements of R. The nil-graph of ideals of R is defined as the graph AG_N(R) whose vertex set is {I:(0)and there exists a non-trivial ideal  such that  and two distinct vertices  
Reza Nikandish
doaj  

Covering a graph by complete bipartite graphs

open access: yesDiscrete Mathematics, 1997
zbMATH Open Web Interface contents unavailable due to conflicting licenses.
Paul Erdös, László Pyber
openaire   +2 more sources

Tumor B‐cell infiltration in platinum‐treated advanced muscle‐invasive urothelial carcinoma

open access: yesMolecular Oncology, EarlyView.
Bladder tumors with higher pretreatment memory B‐cell infiltration were linked to longer survival after cisplatin chemotherapy, but not carboplatin. These tumors also showed more organized immune structures (tertiary lymphoid structures) and a shared pro‐inflammatory B‐cell‐rich community, suggesting that memory B cells may help identify patients most ...
Konrad Stawiski   +10 more
wiley   +1 more source

Liquid biopsy‐based diagnostic evaluation of hypermethylated CpG sites for ovarian cancer diagnosis

open access: yesMolecular Oncology, EarlyView.
This schematic outlines the workflow from biomarker identification to duplex MethyLight assay validation for epithelial ovarian cancer diagnosis using cfDNA‐based liquid biopsy. Initial screening of hypermethylated CpG candidates (cg02957270, cg10061138 cg00480298, COL2A1) was performed in tissue using ARMS‐PCR, COBRA, qPCR and image analysis. Selected
Deepa Bisht   +3 more
wiley   +1 more source

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