Results 81 to 90 of about 26,040 (302)
New types of completeness in metric spaces
, 2014 This paper is devoted to introduce and study two new properties of completeness in the setting of metric spaces. We will call them Bourbaki-completeness and cofinal Bourbaki-completeness.
M. Isabel Garrido +5 more
core +1 more source
Molecular Oncology, EarlyView.Patient‐derived organoids (PDOs) from pancreatic, colorectal, and gastric cancers were used to evaluate standard and experimental therapies. Incorporating cancer‐associated fibroblasts (CAFs) into organoid cultures improved patient therapy outcome prediction.
Marcin Grochowski +12 more
wiley +1 more source
FEBS Open Bio, EarlyView.CRISPRI‐mediated gene silencing and phenotypic exploration in nontuberculous mycobacteria. In this Research Protocol, we describe approaches to control, monitor, and quantitatively assess CRISPRI‐mediated gene silencing in M. smegmatis and M. abscessus model organisms.
Vanessa Point +7 more
wiley +1 more source
The metric completion of the Riemannian space of Kähler metrics
, 2014 Let $X$ be a compact Kähler manifold and $\a \in H^{1,1}(X,\R)$ a Kähler class. We study the metric completion of the space $\HH_\a$ of Kähler metrics in $\a$, when endowed with the Mabuchi $L^2$-metric $d$. Using recent ideas of Darvas, we show that the metric completion $(\overline{\HH}_\a,d)$ of $(\HH_\a,d)$ is a CAT(0) space which can be identified
openaire +3 more sources
Nuclear pore links Fob1‐dependent rDNA damage relocation to lifespan control
FEBS Open Bio, EarlyView.Damaged rDNA accumulates at a specific perinuclear interface that couples nucleolar escape with nuclear envelope association. Nuclear pores at this site help inhibit Fob1‐induced rDNA instability. This spatial organization of damage handling supports a functional link between nuclear architecture, rDNA stability, and replicative lifespan in yeast.
Yamato Okada +5 more
wiley +1 more source
, 2019 The theory of boundary regularity for p-harmonic functions is extended to unbounded open sets in complete metric spaces with a doubling measure supporting a p-Poincare inequality, 1 amp;lt; p amp;lt; infinity.
Björn, Anders, +5 more
core +1 more source
Fixed Point Theory in α-Complete Metric Spaces with Applications [PDF]
, 2014 The aim of this paper is to introduce new concepts of α-η-complete metric space and α-η-continuous function and establish fixed point results for modified α-η-ψ-rational contraction mappings in α-η-complete metric spaces.
P. Salimi, N. Hussain, M. A. Kutbi
core +1 more source
Promiscuous stimulation of HSP70 ATPase activity by parasite‐derived J‐domains
FEBS Open Bio, EarlyView.The malaria parasite Plasmodium falciparum exports three highly homologous yet functionally divergent J‐domain proteins into human erythrocytes. Here, we show that J‐domains isolated from all three proteins effectively stimulate the ATPase activity of both endogenous host and exported parasite HSP70 chaperones.
Julian Barth +6 more
wiley +1 more source
On the Yoneda completion of a quasi-metric space
Theoretical Computer Science, 2002 The authors consider two notions for the completion of rather general classes of topological spaces: the Yoneda completion of generalized metric spaces and the Smyth completion. (Such considerations are motivated in part by earlier efforts to reconcile continuous domain theory and metric space theory within a common framework.) A net-theoretic version ...
Hans-Peter A. Künzi +1 more
openaire +2 more sources
FEBS Open Bio, EarlyView.Amino acids sequence of two different proteins with the same sequence (chameleon sequence—black boxes) represent in 3D structure of the proteins different secondary structures: HHHH—helical and BBB—Beta‐structural. The chains folded in water environment adopt different III‐order structures in which the chameleon fragments appear to adopt similar status
Irena Roterman +4 more
wiley +1 more source