Results 81 to 90 of about 23,512 (262)
Molecular Oncology, EarlyView.BCL9 and BCL9L drive bladder cancer progression by enhancing β‐catenin signaling, promoting proliferation, migration, invasion, and organoid growth. Genetic depletion of BCL9(L) suppresses malignant phenotypes, while pharmacological disruption of the β‐catenin/BCL9(L) complex with ZW4864 inhibits canonical Wnt signaling and tumor‐associated cellular ...
Roland Kotolloshi +11 more
wiley +1 more source
Nonlinear Contractions in 0-Complete Partial Metric Spaces
Abstract and Applied Analysis, 2012 Using the setting of 0-complete partial metric spaces, some common fixed point results of maps that satisfy the nonlinear contractive conditions are obtained.
Abd Ghafur Bin Ahmad +3 more
doaj +1 more source
Common Best Proximity Point Theorems in Neutrosophic Complete Metric Spaces [PDF]
Neutrosophic Sets and SystemsIn this work, we provide the existence of common best proximity point for a given pair of non-self mappings in non-Archimedean neutrosophic complete metric spaces.
V. Pragadeeswarar, A. Sreelakshmi Unni
doaj +1 more source
Molecular Oncology, EarlyView.Circulating microRNAs as biomarkers of cachexia and sex‐specific cancer in senior dogs. In 25 client‐owned dogs, four circulating miRNAs (miR‐15a, miR‐15b, miR‐16, miR‐140) were downregulated in cachexia, with miR‐16 the strongest individual biomarker (AUC = 0.899).
Soon‐Seok Park +6 more
wiley +1 more source
Molecular Oncology, EarlyView.Single‐cell DNA methylation (scDNAme) profiling maps epimutational clonal evolution, revealing mechanisms of malignancy and therapeutic resistance across diverse cancer types. By providing a high‐resolution landscape of intratumoral heterogeneity, these technologies empower precise patient stratification, guide the development of enhanced ...
Ik Soo Kim
wiley +1 more source
Molecular Oncology, EarlyView.Interferon type 1 (IFN‐1) production and signaling is associated with the acquisition of therapy resistance, following chronic DNA damage, via Interferon‐related DNA damage resistance signature (IRDS) gene expression. An alternative, DNA damage‐independent role of sustained IFN‐1 mediated resistance was identified and characterized by the emergence of ...
Ashlyn Conant +11 more
wiley +1 more source
Generalized multivalued $F$-weak contractions on complete metric spaces [PDF]
Sahand Communications in Mathematical Analysis, 2015 In this paper, we introduce the notion of generalized multivalued $F$- weak contraction and we prove some fixed point theorems related to introduced contraction for multivalued mapping in complete metric spaces.
Hossein Piri, Samira Rahrovi
doaj
Spatial biology in cancer epigenetics
Molecular Oncology, EarlyView.Spatial epigenomics combines molecular profiling with tissue architecture to reveal how gene regulation is organized within intact tissues. In cancer, these technologies uncover the mechanisms driving tumor heterogeneity and microenvironmental interactions, opening new opportunities for biomarker discovery and precision medicine.
Eva Crespo‐García, Manel Esteller
wiley +1 more source
Completion Of Cone Metric Spaces
, 2009 In this paper a completion theorem for cone metric spaces and a completion theorem for cone normed spaces are proved. The completion spaces are defined by means of an equivalence relation obtained by convergence via the scalar norm of the Banach space E.
openaire +3 more sources
Molecular Oncology, EarlyView.The cell‐autonomous roles of interferon type 1 vary based on duration and intensity. While acute, robust signaling results in cancer cell cytotoxic effects, sustained, low‐level signaling is associated with tumor‐promoting effects. This review summarizes current research of IFN‐1 in cancer and within the clinical setting, with an emphasis on female ...
Ashlyn Conant +7 more
wiley +1 more source