Results 111 to 120 of about 167,627 (310)

Discordant evolution of mitochondrial and nuclear yeast genomes at population level

BMC Biology, 2020
Background Mitochondria are essential organelles partially regulated by their own genomes. The mitochondrial genome maintenance and inheritance differ from the nuclear genome, potentially uncoupling their evolutionary trajectories.
Matteo De Chiara, Anne Friedrich, Benjamin Barré, Michael Breitenbach, Joseph Schacherer, Gianni Liti   +5 more
doaj   +1 more source

Scaling laws in bacterial genomes: A side-effect of selection of mutational robustness?

, 2010
In the past few years, numerous research projects have focused on identifying and understanding scaling properties in the gene content of prokaryote genomes and the intricacy of their regulation networks.
Beslon, Guillaume, Knibbeb, Carole, Y. Sanchez-Dehesa, Parsons, David,, G. Beslon, Peña Sanchez, Jose Maria, D.P. Parsons, Parsons, David, P., Knibbe, Carole, Sanchez Dehesa, Yolanda, Parsons, David, Peña, Jose-Maria, C. Knibbe, J.-M. Peña, Sanchez-Dehesa, Yolanda   +14 more
core   +1 more source

Antifolding activity of hsp60 couples protein import into the mitochondrial matrix with export to the intermembrane space [PDF]

, 1992
Cytochrome b2 reaches the intermembrane space of mitochondria by transport into the matrix followed by export across the inner membrane. While in the matrix, the protein interacts with hsp60, which arrests its folding prior to export.
Ostermann, Joachim, Hartl, Franz-Ulrich, Rassow, Joachim, Neupert, Walter, Horwich, Arthur, Horwich, Arthur L., Koll, Hans, Guiard, Bernard   +7 more
core   +1 more source

The first complete mitochondrial genome of Grossulariaceae: Molecular features, structure recombination, and genetic evolution

BMC Genomics
Background Mitochondria play crucial roles in the growth, development, and adaptation of plants. Blackcurrant ( Ribes nigrum L.) stands out as a significant berry species due to its rich nutritional profile, medicinal properties, and health benefits ...
Guilong Lu, Wenhua Wang, Shanshan Zhang, Guang Yang, Kun Zhang, Y. Que, Lan-lan Deng   +6 more
semanticscholar   +1 more source

Bioadhesive Hydrogel With Polyphenol‐Armored Nanogene Rejuvenates Chondrocyte Senescence for Aged Osteoarthritis Therapy

Advanced Science, EarlyView.
An adhesive hydrogel depot with polyphenol‐armored nanogenes is developed for treating aged osteoarthritis. This system maintains miR‐140 bioactivity, prolongs its intra‐articular retention, and enhances transfection into chondrocytes, leading to the downregulation of senescence‐associated pathways.
Liwei Yan, Runze Yang, Ting Zhou, Tianhao Xu, Yongqi Li, Yuelin Hu, Minghao Ge, Lei Zhang, Xiong Lu, Chaoming Xie, Weili Fu   +10 more
wiley   +1 more source

Plasticity of repetitive sequences demonstrated by the complete mitochondrial genome of Eucalyptus camaldulensis

Frontiers in Plant Science
The tree Eucalyptus camaldulensis is a ubiquitous member of the Eucalyptus genus, which includes several hundred species. Despite the extensive sequencing and assembly of nuclear genomes from various eucalypts, the genus has only one fully annotated and ...
Yoshinori Fukasawa, Patrick Driguez, S. Bougouffa, K. Carty, Alexander Putra, M. Cheung, L. Ermini   +6 more
semanticscholar   +1 more source

Targeting Endogenous Lipophagy: A Novel Strategy to Enhance MSC Osteogenesis and Mineralization for Senile Osteoporosis Therapy

Advanced Science, EarlyView.
Schematic representation of the role of lipophagy in bone mesenchymal stem cells(MSCs). In healthy MSCs, functional lipophagy efficiently degrades lipid droplets to support oxidative phosphorylation and cellular energy production, thereby facilitating osteogenic differentiation and matrix mineralization.
Chaoqiang Chen, Zhidong Liu, Yanhang Sun, Xiaojun Xu, Zhexiao Lan, Junhao Zhao, Peitao Xu, Guiwen Ye, Jinteng Li   +8 more
wiley   +1 more source

Lilium tsingtauense，the first complete mitochondrial genome of Lilium

, 2023
 Lilium is a horticultural flower with significant commercial value that combines ornamental, edible and medicinal values. The Lilium chloroplast genome has been reported; however, the sequence of its mitochondrial genome is still lacking.
Dan Liu (13880492)
core   +1 more source

Integrated Single‐Cell and Spatial Analysis Reveals a Metabolic‐Immune Axis Driving Aortic Dissection

Advanced Science, EarlyView.
Single‐cell and spatial profiling of 110 human thoracic aortic samples reveals a stromal–immune circuit driving aortic dissection. An elastin‐rich fibroblast subset is depleted with age and markedly reduced in disease, weakening aortic wall integrity.
Jing Tao, Huanjie Yang, Jiahui Yong, Xueting Chen, Qiang Zhao, Xueli Wu, Lei Yan, Li Pang, Fan Luo, Mengjun Yu, Shanshan Pan, Deyang Li, Rouxi Chen, Juan Wang, Zhensheng Dong, Fan Yang, Yue Wang, Yang Chen, Hongjian Zheng, Zhimin Yang, Zijie Wang, Karsten Kristiansen, Hui Peng, Xiaodong Fang, Juan Shen, Yining Yang   +25 more
wiley   +1 more source

A unique genetic code change in the mitochondrial genome of the parasitic nematode Radopholus similis

BMC Research Notes, 2009
Background Mitochondria (mt) contain their own autonomously replicating DNA, constituted as a small circular genome encoding essential subunits of the respiratory chain.
Van Leeuwen Thomas, Vanholme Bartel, Jacob Joachim EM, Gheysen Godelieve   +3 more
doaj   +1 more source