Results 121 to 130 of about 447,624 (394)

Class IIa HDACs forced degradation allows resensitization of oxaliplatin‐resistant FBXW7‐mutated colorectal cancer

open access: yesMolecular Oncology, EarlyView.
HDAC4 is degraded by the E3 ligase FBXW7. In colorectal cancer, FBXW7 mutations prevent HDAC4 degradation, leading to oxaliplatin resistance. Forced degradation of HDAC4 using a PROTAC compound restores drug sensitivity by resetting the super‐enhancer landscape, reprogramming the epigenetic state of FBXW7‐mutated cells to resemble oxaliplatin ...
Vanessa Tolotto   +13 more
wiley   +1 more source

Complete mitochondrial DNA and phylogenetic study of qionglai native black chicken

open access: yesMATEC Web of Conferences, 2016
The complete mitochondrial genome sequence of the qionglai black chicken was measured by PCR-based methods, the molecular characterization and phyletic evolution analyzed in detail.
Hu Yaodong   +3 more
doaj   +1 more source

First record of the complete mitochondrial genome of Tubifex tubifex (Müller) 1774 (Annelida; Clitellata; Oligochaeta) and phylogenetic analysis

open access: yesMitochondrial DNA. Part B. Resources, 2022
The complete mitochondrial genome of Tubifex tubifex was analyzed using the MGISEQ-2000 platform. The size of the complete mitochondrial genome was 15,972 bp. Data pertaining to the genome, such as the presence of 13 protein-coding genes (PCGs), two rRNA
Jeounghee Lee, Jongwoo Jung
doaj   +1 more source

Mitochondrial Genome of Savalia savaglia (Cnidaria, Hexacorallia) and Early Metazoan Phylogeny [PDF]

open access: yes, 2018
Mitochondrial genomes have recently become widely used in animal phylogeny, mainly to infer the relationships between vertebrates and other bilaterians. However, only 11 of 723 complete mitochondrial genomes available in the public databases are of early
Chevaldonné, P.   +2 more
core  

Plasmodium vivax-like genome sequences shed new insights into Plasmodium vivax biology and evolution [PDF]

open access: yes, 2018
Although Plasmodium vivax is responsible for the majority of malaria infections outside Africa, little is known about its evolution and pathway to humans. Its closest genetic relative, P.
Arnathau, Céline   +15 more
core   +4 more sources

Assembly and comparative analysis of complete mitochondrial genome sequence of an economic plant Salix suchowensis

open access: yesPeerJ, 2017
Willow is a widely used dioecious woody plant of Salicaceae family in China. Due to their high biomass yields, willows are promising sources for bioenergy crops.
Ning Ye   +6 more
semanticscholar   +1 more source

Complete mitochondrial genome sequence of Aequorea coerulescens [PDF]

open access: yesMitochondrial DNA Part B, 2019
The complete mitochondrial genome sequences of hydromedusa Aequorea coerulescens, a dominant giant jellyfish distributing in the Yellow Sea and northern East China Sea, China, is first reported in this research. Its mitochondrial DNA has 14,804 bp in length with a linear structure, containing 13 protein-coding genes (PCGs), 2rRNA (s-rRNA and l-rRNA ...
Jianing Lin, Song Feng, Lijuan Wang
openaire   +3 more sources

Transcriptional network analysis of PTEN‐protein‐deficient prostate tumors reveals robust stromal reprogramming and signs of senescent paracrine communication

open access: yesMolecular Oncology, EarlyView.
Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice   +16 more
wiley   +1 more source

The complete mitochondrial genome of grey-headed canary-flycatcher (Culicicapa ceylonensis, Muscicapidae, Passeriformes)

open access: yesMitochondrial DNA. Part B. Resources, 2019
In our research, the complete mitochondrial genome of Culicicapa ceylonensise was determined and described, which was the first complete mitogenome reported in the Culicicapa. The complete mitochondrial genome sequence of C. ceylonensise was 16,851 bp in
Hongmei Tu   +5 more
doaj   +1 more source

Characterization of the complete mitochondrial genome of the white grouper Epinephelus aeneus (Perciformes, Serranidae) and a comparative analysis with other Serranidae species

open access: yesMitochondrial DNA. Part B. Resources, 2020
The complete mitochondrial genome of the white grouper Epinephelus aeneus, which belongs to the family Serranidae, was determined. The complete mitochondrial genome measured 16,578 bp in length and consisted of 13 protein-coding genes, 22 tRNA genes, 2 ...
Seungki Lee   +3 more
doaj   +1 more source

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