Results 131 to 140 of about 4,406,015 (337)

Internationalization process and complex adaptive systems

open access: yesInternext: Revista Eletrônica de Negócios Internacionais, 2017
This article aims to analyze the characteristics of the internationalization process of companies from the Santa Cruz do Capibaribe clothing hub in Pernambuco, considering the Complex Adaptive Systems approach.
Rennaly Alves da Silva   +2 more
doaj   +1 more source

TRAIL‐PEG‐Apt‐PLGA nanosystem as an aptamer‐targeted drug delivery system potential for triple‐negative breast cancer therapy using in vivo mouse model

open access: yesMolecular Oncology, EarlyView.
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat   +8 more
wiley   +1 more source

Managing schools as complex adaptive systems: A strategic perspective

open access: yes, 2017
This conceptual study examines the analogies between schools and complex adaptive systems and identifies strategies used to manage schools as complex adaptive systems.
Tuncer Fidan, A. Balcı
semanticscholar   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

open access: yesMolecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Information systems development projects as complex adaptive systems [PDF]

open access: yes, 2012
This research considers information systems development (ISD) projects as complex adaptive systems. We investigate the question whether complex adaptive systems (CAS) theory is relevant as a theoretical foundation for understanding ISD, and if so, which ...
Kautz, Karlheinz
core   +2 more sources

Circular RNA expression landscapes in myelodysplastic neoplasms: Associations with mutational signatures and disease progression

open access: yesMolecular Oncology, EarlyView.
In this explorative study, the abundance of circular RNA molecules in bone marrow stem cells was found to be elevated in patients with high‐risk myelodysplastic neoplasms, and to be associated with an increased risk of progression to acute myeloid leukemia.
Eileen Wedge   +17 more
wiley   +1 more source

Complex adaptive systems, socio-ecological systems and resilience [PDF]

open access: yes, 2015
The study and analysis of global risk increase from the environmental crisis resulting from a greater number of interactions and feedbacks between social, economic, political and environmental problems in different spatial and temporal scales require an ...
CASTILLO VILLANUEVA, MARIA LOURDES   +3 more
core  

Subtype‐specific enhancer RNAs define transcriptional regulators and prognosis in breast cancers

open access: yesMolecular Oncology, EarlyView.
This study employed machine learning methodologies to perform the subtype‐specific classification of RNA‐seq data sets, which are mapped on enhancers from TCGA‐derived breast cancer patients. Their integration with gene expression (referred to as ProxCReAM eRNAs) and chromatin accessibility profiles has the potential to identify lineage‐specific and ...
Aamena Y. Patel   +6 more
wiley   +1 more source

Modeling Complex Systems [PDF]

open access: yes
Empirical observations suggest that linear dynamics are not an adequate representa- tion of ecological systems and that a realistic representation would require adoption of complex nonlinear dynamical systems with characteristics encountered in complex ...
XEPAPADEAS, Anastasios
core   +1 more source

Interactions of Self-organizing Systems in Nature [PDF]

open access: yes, 2011
Nature essentially consists of complex systems. The paper presents a conceptual framework to understand how complex systems interact with each other in nature. All natural systems are thermodynamically open and physically adaptive.
Chatterjee, Mr. Atanu Bikash
core  

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