Results 141 to 150 of about 4,406,015 (337)
Molecular Oncology, EarlyView.Dimethyl fumarate (DMF) reduces growth of HPV‐positive cervical cancer spheroids and induces ferroptosis in cervical cancer cells via blocking SLC7A11/Glutathione (GSH) axis. Combination of subcytotoxic doses of DMF and cisplatin (CDDP) further suppresses spheroid growth and drives cell death in 2D culture models.
Carolina Punziano +6 more
wiley +1 more source
Targeted modulation of IGFL2‐AS1 reveals its translational potential in cervical adenocarcinoma
Molecular Oncology, Volume 20, Issue 6, Page 1643-1660, June 2026.Cervical adenocarcinoma patients face worse outcomes than squamous cell carcinoma counterparts despite similar treatment. The identification of IGFL2‐AS1's differential expression provides a molecular basis for distinguishing these histotypes, paving the way for personalized therapies and improved survival in vulnerable populations globally.
Ricardo Cesar Cintra +6 more
wiley +1 more source
Complex Adaptive Systems of Systems: A Grounded Theory Approach
Grounded Theory Review: An International Journal, 2018 This paper details the classic grounded theory approach used in a research project to develop a conceptual theory for an engineering solution to address highly complex problems.
Bonnie Johnson +3 more
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Molecular Oncology, EarlyView.Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson +9 more
wiley +1 more source
Tạp chí Khoa học và Công nghệIn the context of applying artificial intelligence to the legal domain, building legal question-answering (QA) systems requires a structured, queryable, and inferable knowledge foundation.
Huynh Le Huy +2 more
doaj +1 more source
Complex adaptive systems in CanMEDS 2025. [PDF]
Can Med Educ J, 2023 Van Aerde J +4 more
europepmc +1 more source
Analytics and complexity: learning and leading for the future [PDF]
, 2012 There is growing interest in the application of learning analytics to manage, inform and improve learning and teaching within higher education. In particular, learning analytics is seen as enabling data-driven decision making as universities are seeking ...
Beer, Colin, Clark, Damien, Jones, David
core +1 more source
COMP–PMEPA1 axis promotes epithelial‐to‐mesenchymal transition in breast cancer cells
Molecular Oncology, EarlyView.This study reveals that cartilage oligomeric matrix protein (COMP) promotes epithelial‐to‐mesenchymal transition (EMT) in breast cancer. We identify PMEPA1 (protein TMEPAI) as a novel COMP‐binding partner that mediates EMT via binding to the TSP domains of COMP, establishing the COMP–PMEPA1 axis as a key EMT driver in breast cancer.
Konstantinos S. Papadakos +6 more
wiley +1 more source
Molecular Oncology, EarlyView.Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang +12 more
wiley +1 more source
Detection of ChatGPT fake science with the xFakeSci learning algorithm
Scientific ReportsGenerative AI tools exemplified by ChatGPT are becoming a new reality. This study is motivated by the premise that “AI generated content may exhibit a distinctive behavior that can be separated from scientific articles”.
Ahmed Abdeen Hamed, Xindong Wu
doaj +1 more source