Results 71 to 80 of about 1,254,353 (318)

Probing the druggability of membrane-bound Rab5 by molecular dynamics simulations

Journal of Enzyme Inhibition and Medicinal Chemistry, 2017
Rab5 is a small GTPase and a key regulator in early endosomal trafficking. Rab5 and its effectors are involved in a large number of infectious diseases and certain types of cancer.
Eileen Edler, Matthias Stein
doaj   +1 more source

Cell-free N-glycosylation of peptides using synthetic lipid-linked hybrid and complex N-glycans

Frontiers in Molecular Biosciences, 2023
Cell-free, chemoenzymatic platforms are emerging technologies towards generating glycoconjugates with defined and homogeneous glycoforms. Recombinant oligosaccharyltransferases can be applied to glycosylate “empty,” i.e., aglycosyalted, peptides and ...
Lisa Wenzel, Marcus Hoffmann, Erdmann Rapp, Erdmann Rapp, Thomas F. T. Rexer, Udo Reichl, Udo Reichl   +6 more
doaj   +1 more source

A Bibliometric Analysis of Publications in Uremic Toxins From 1991 to 2024

Therapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Background Uremic toxins are a growing area of research in nephrology, with significant implications in the progression and treatment of chronic kidney disease (CKD) and the management of end‐stage kidney disease (ESKD). This bibliometric analysis aims to evaluate the global research trends, key contributors, and the impact of publications in ...
Yuh‐Shan Ho, Karim M. Soliman, Wisit Cheungpasitporn, Wannasit Wathanavasin, Ahmed Daoud, Ahmed I. Kamal, Balázs Szamosfalvi, Tibor Fülöp   +7 more
wiley   +1 more source

Lipid Fingerprints and Cofactor Dynamics of Light-Harvesting Complex II in Different Membranes [PDF]

, 2019
Plant light-harvesting complex II (LHCII) is the key antenna complex for plant photosynthesis. We present coarse-grained molecular dynamics simulations of monomeric and trimeric LHCII in a realistic thylakoid membrane environment based on the Martini ...
Thallmair, Sebastian, Marrink, Siewert J.; id_orcid, Vainikka, Petteri A.; id_orcid, Marrink, Siewert J., Vainikka, Petteri A.   +4 more
core   +1 more source

Serum Myonectin Levels Are Positively Associated With Physical Function and Lower Frailty‐Related Limitation in Maintenance Hemodialysis Patients: A Cross‐Sectional Study

Therapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Background Maintenance hemodialysis (MHD) patients frequently suffer from frailty, characterized by reduced physical function and poor prognosis. Myokines, such as myonectin, secreted by muscle, are emerging regulators of systemic health. This study investigated the relationship between serum myonectin, adipokines (adiponectin, omentin), and ...
Kenichi Kono, Yoshifumi Moriyama, Koji Ohashi, Naoya Otaka, Minako Tatsumi, Toyoaki Murohara, Noriyuki Ouchi, Satoru Oshima   +7 more
wiley   +1 more source

Presentation of the Action IS1104- The EU in the new complex geography of economic systems: models, tools and policy evaluation. Modelling geographical systems as complex networks. [PDF]

, 2014
The training school is organized within the ISCH COST ACTION IS1104 project on “The EU in the new complex geography of economic systems: models, tools and policy evaluation” (http://www.gecomplexity-cost.eu/home/).
COMMENDATORE, PASQUALE
core  

Delay of cognitive gamma responses in Alzheimer's disease

NeuroImage: Clinical, 2016
Event-related oscillations (EROs) reflect cognitive brain dynamics, while sensory-evoked oscillations (SEOs) reflect sensory activities. Previous reports from our lab have shown that those with Alzheimer's disease (AD) or mild cognitive impairment (MCI ...
Erol Başar, Derya Durusu Emek-Savaş, Bahar Güntekin, Görsev G. Yener   +3 more
doaj   +1 more source

Forecasting the Dialysis Burden in Japan: Validation‐Based Projections of Prevalence and Incidence Through 2050

Therapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Background Japan has one of the highest dialysis prevalence rates worldwide and a shrinking, aging population. Whether dialysis burden has entered a sustained post‐peak phase or whether recent declines partly reflect pandemic‐related disruptions remains uncertain.
Hatice Şahin, Berrak Itır Aylı, Nüket Paksoy   +2 more
wiley   +1 more source

Research on Dynamic Modeling and Control of Magnetorheological Hydro-Pneumatic Suspension

Actuators
A novel magnetorheological semi-active hydro-pneumatic suspension system was proposed to overcome the shortcoming of the traditional hydro-pneumatic suspension without adaptive vibration damping function. It is based on the magnetorheological semi-active
Yuansi Chen, Min Jiang, Fufeng Yang, Ruijing Qian, Rongjie Zhai, Hongliang Wang, Shaoqing Xv   +6 more
doaj   +1 more source

Removable Dyes—The Missing Link for In-Depth N-Glycan Analysis via Multi-Method Approaches

Engineering, 2023
As the roles of glycans in health and disease continue to be unraveled, it is becoming apparent that glycans’ immense complexity cannot be ignored.
Samanta Cajic, René Hennig, Valerian Grote, Udo Reichl, Erdmann Rapp   +4 more
doaj   +1 more source