Results 81 to 90 of about 1,254,353 (318)

Enteropathogenic E. coli shows delayed attachment and host response in human jejunum organoid‐derived monolayers compared to HeLa cells

FEBS Letters, EarlyView.
Enteropathogenic E. coli (EPEC) infects the human intestinal epithelium, resulting in severe illness and diarrhoea. In this study, we compared the infection of cancer‐derived cell lines with human organoid‐derived models of the small intestine. We observed a delayed in attachment, inflammation and cell death on primary cells, indicating that host ...
Mastura Neyazi, Pilar Samperio Ventayol, Natalie Burkard, Nicolas Schlegel, Carmen Aguilar, Sina Bartfeld   +5 more
wiley   +1 more source

Co-evolutionary analysis: a policy exploration method for system dynamics models [PDF]

, 2013
Journal articleIn system dynamics (SD), complex nonlinear systems can generate a wide range of possible behaviours that frequently require search and optimization algorithms in order to explore optimal policies. Within the SD literature, the conventional
Hongliang, Liu, Duggan, Jim, Howley, Enda   +2 more
core   +1 more source

Application of an Inclined Settler for Cell Culture-Based Influenza A Virus Production in Perfusion Mode

Frontiers in Bioengineering and Biotechnology, 2020
Influenza viruses have been successfully propagated using a variety of animal cell lines in batch, fed-batch, and perfusion culture. For suspension cells, most studies reported on membrane-based cell retention devices typically leading to an accumulation
Juliana Coronel, Gwendal Gränicher, Volker Sandig, Thomas Noll, Yvonne Genzel, Udo Reichl, Udo Reichl   +6 more
doaj   +1 more source

Organoids in pediatric cancer research

FEBS Letters, EarlyView.
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley   +1 more source

Complex dynamics emerging in Rule 30 with majority memory [PDF]

, 2010
In cellular automata with memory, the unchanged maps of the conventional cellular automata are applied to cells endowed with memory of their past states in some specified interval.
Martinez, Genaro J., Mora, Juan C.S.T, Adamatzky, Andrew, Alonso-Sanz, Ramon   +3 more
core  

Partial Transfer Ensemble Learning Framework: A Method for Intelligent Diagnosis of Rotating Machinery Based on an Incomplete Source Domain

Sensors, 2022
Most cross-domain intelligent diagnosis approaches presume that the health states in training datasets are consistent with those in testing. However, it is usually difficult and expensive to collect samples under all failure states during the training ...
Gang Mao, Zhongzheng Zhang, Sixiang Jia, Khandaker Noman, Yongbo Li   +4 more
doaj   +1 more source

Reciprocal control of viral infection and phosphoinositide dynamics

FEBS Letters, EarlyView.
Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley   +1 more source

Dynamical 2-Complexes

Geometriae Dedicata, 2001
We introduce the class of dynamical 2-complexes. These complexes allow us to obtain in particular a topological representation of any free group automorphism.
openaire   +2 more sources

Spatiotemporal and quantitative analyses of phosphoinositides – fluorescent probe—and mass spectrometry‐based approaches

FEBS Letters, EarlyView.
Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho, Shin Morioka, Junko Sasaki, Takehiko Sasaki   +3 more
wiley   +1 more source

Developing an oncolytic Newcastle disease virus production process with EB66 cells

Applied Microbiology and Biotechnology
Newcastle disease virus (NDV) has been the subject of extensive research as a potential oncolytic virus for various types of cancer. While clinical studies are ongoing, the manufacturing of high NDV doses on a large scale is challenging.
Lennart Jacobtorweihe, Annabelle Saulnier, Arnaud Léon, Yvonne Genzel, Udo Reichl   +4 more
doaj   +1 more source