Results 101 to 110 of about 1,920,825 (260)

Phylogenetic and developmental analyses indicate complex functions of calcium-activated potassium channels in zebrafish embryonic development. [PDF]

Dev Dyn, 2021
Silic MR, Black MM, Zhang G.
europepmc   +1 more source

PICALM::MLLT10 translocated leukemia

FEBS Letters, EarlyView.
This comprehensive review of PICALM::MLLT10 translocated acute leukemia provides an in‐depth review of the structure and function of CALM, AF10, and the fusion oncoprotein (1). The multifaceted molecular mechanisms of oncogenesis, including nucleocytoplasmic shuttling (2), epigenetic modifications (3), and disruption of endocytosis (4), are then ...
John M. Cullen, Antonia C. Nakatsugawa, Natalie Barton, Henry Haines, Gary S. Stein, Janet L. Stein, Daniel S. Wechsler, Jessica L. Heath   +7 more
wiley   +1 more source

Manifold functions of Mediator complex in neurodevelopmental disorders

Neurobiology of Disease
Neurodevelopmental disorders (NDDs) encompass a diverse range of impairments affecting brain development and functions, often presenting as deficits in motor skills, cognitive abilities, language development and neuropsychiatric health.
Yi-Wei Li, Si-Xin Tu, Ze-Xuan Li, Yu-Qiang Ding, Ling Hu   +4 more
doaj   +1 more source

Protein kinase PIM2: A simple PIM family kinase with complex functions in cancer metabolism and therapeutics. [PDF]

J Cancer, 2021
Wang Y, Xiu J, Ren C, Yu Z.
europepmc   +1 more source

Cell wall target fragment discovery using a low‐cost, minimal fragment library

FEBS Letters, EarlyView.
LoCoFrag100 is a fragment library made up of 100 different compounds. Similarity between the fragments is minimized and 10 different fragments are mixed into a single cocktail, which is soaked to protein crystals. These crystals are analysed by X‐ray crystallography, revealing the binding modes of the bound fragment ligands.
Kaizhou Yan, Mathew Stanley, Olawale Raimi, Andrew T. Ferenbach, Helge C Dorfmueller, Daan M. F. van Aalten   +5 more
wiley   +1 more source

Retracted: General Complex-Valued Overlap Functions

Journal of Mathematics, 2023
Journal of Mathematics
doaj   +1 more source

The (Glg)ABCs of cyanobacteria: modelling of glycogen synthesis and functional divergence of glycogen synthases in Synechocystis sp. PCC 6803

FEBS Letters, EarlyView.
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee, Dimitrios Bekiari, Sofia Doello, Karl Forchhammer   +3 more
wiley   +1 more source

Second-order complex linear differential equations with special functions or extremal functions as coefficients

Electronic Journal of Differential Equations, 2015
The classical problem of finding conditions on the entire coefficients A(z) and B(z) guaranteeing that all nontrivial solutions of $f''+A(z)f'+B(z)f=0$ are of infinite order is discussed. Two distinct approaches are used.
Xiubi Wu, Jianren Long, Janne Heittokangas, Ke-e Qiu   +3 more
doaj  

The CRK2-CYC13 complex functions as an S-phase cyclin-dependent kinase to promote DNA replication in Trypanosoma brucei. [PDF]

BMC Biol, 2021
Lee KJ, Li Z.
europepmc   +1 more source

Structural biology of ferritin nanocages

FEBS Letters, EarlyView.
Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley   +1 more source