Results 51 to 60 of about 2,236,870 (266)

Cholesterol lowering drug may influence cellular immune response by altering MHC II function[S]

Journal of Lipid Research, 2013
Major histocompatibility complex class II (MHC II) expressed on the surface of antigen-presenting cells (APCs) displays peptides to CD4+ T cells. Depletion of membrane cholesterol from APCs by methyl β-cyclodextrin treatment compromises peptide-MHC II ...
Koushik Roy, Moumita Ghosh, Tuhin Kumar Pal, Saikat Chakrabarti, Syamal Roy   +4 more
doaj   +1 more source

Guidelines for Pediatric Radiotherapy Simulation: A Report From the Children's Oncology Group Radiation Oncology Discipline

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Pediatric radiation therapy presents unique challenges compared to adult treatments, including those of immobilization, potential need for sedation, and the critical importance of accurate, reproducible positioning. Additionally, heightened attention to imaging doses is necessary to minimize long‐term toxicity in survivors.
Parham Alaei, Stephen Mihalcik, Sujith Baliga, Young Kwok, Dana Casey, Eric Ehler, Christiane Burton, John C. Breneman, Daphne A. Haas‐Kogan, Suzanne L. Wolden, Arnold C. Paulino, Nadia N. Laack, Natia Esiashvili, Sarah Milgrom, Christine Hill‐Kayser, Thomas J. Fitzgerald, John A. Kalapurakal, Chia‐Ho Hua   +17 more
wiley   +1 more source

Effect of removing the spring flush and irrigation on the reflowering and late ripening of cactus pear Opuntia ficus-indica (L.) Mill.

Acta Agriculturae Slovenica, 2023
The effect of removing the spring flush and three irrigation doses on cactus pear’s reflowering and late ripening were studied. Removing the spring flush (scozzolatura practice) and irrigation have a significant effect (p ≤ 0,05) on the reflowering and ...
Mohamed ARBA, Achraf ESSABIRI
doaj   +1 more source

Improved Early Referral in Long‐Term Survivor Care With Institutional Standardized Practice Among Childhood Leukemia Survivors#

Pediatric Blood &Cancer, EarlyView.
ABSTRACT In 2018, the Texas Children's Cancer and Hematology Center Leukemia Program implemented a practice standard to support the transition from treatment to survivorship that includes shared, alternating care between leukemia and survivorship clinicians and a reminder to refer survivors to the long‐term survivor clinic (LTSC) 2 years after ...
Ji Yun Tark, Kayla L. Foster, Omar Shakeel, Mary C. Shapiro, Shawki L. Qasim, ZoAnn Dreyer, Eric S. Schafer, Ashley M. Butler, Austin L. Brown, Maria Monica Gramatges   +9 more
wiley   +1 more source

The role of complex II in disease

Biochimica et Biophysica Acta (BBA) - Bioenergetics, 2013
Genetically defined mitochondrial deficiencies that result in the loss of complex II function lead to a range of clinical conditions. An array of tumor syndromes caused by complex II-associated gene mutations, in both succinate dehydrogenase and associated accessory factor genes (SDHA, SDHB, SDHC, SDHD, SDHAF1, SDHAF2), have been identified over the ...
Hoekstra, A.S., Bayley, J.P.
openaire   +4 more sources

Personalized Zebrafish Models for Fusion‐Positive Pediatric Sarcomas

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Clinical sequencing efforts have revolutionized our approaches to categorizing pediatric cancers in real time. This has dramatically improved our ability to profile pediatric tumors, identify actionable vulnerabilities, and influence clinical care.
Lisa H. Hall, Emma N. Harrison, Genevieve C. Kendall   +2 more
wiley   +1 more source

Copper(II), Nickel(II) and Zinc(II) Complexes of Peptide Fragments of Tau Protein

Molecules
Copper(II), nickel(II) and zinc(II) complexes of various peptide fragments of tau protein were studied by potentiometric and spectroscopic techniques. All peptides contained one histidyl residue and represented the sequences of tau(91–97) (Ac-AQPHTEI-NH2)
Zsuzsa Kastal, Adrienn Balabán, Szilvia Vida, Csilla Kállay, Lajos Nagy, Katalin Várnagy, Imre Sóvágó   +6 more
doaj   +1 more source

The Role of “Adult‐Onset” Cancer Predisposition Genes in Pediatric Cancer: A Comprehensive Review

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Current literature estimates that 10% of pediatric cancers are caused by pathogenic or likely pathogenic (P/LP) germline variants in cancer predisposition genes (CPGs). Variants in CPGs thought to increase cancer risk exclusively during adulthood are referred to as “adult‐onset” CPGs (aoCPGs).
Maria Rozo, Miriam A. Bornhorst, Angela J. Waanders, Sara Zarnegar‐Lumley, Ashwin Lakshman Koppayi, Lucy A. Godley   +5 more
wiley   +1 more source

Synthesis and characterization of zinc(II), palladium(II) and platinum(II) complex with 2’-[1-(2-pyridinyl)ethylidene] oxamohydrazide. The crystal structure of bis{2’-[1-(2-pyridinyl)ethylidene]oxamohydrazido}zinc(II) trihydrate [PDF]

Journal of the Serbian Chemical Society, 2004
Complexes of Zn(II), Pd(II) and Pt(II) with 2’-[1-(2-pyridinyl)ethylidene]oxamohydrazide (Hapsox) were synthesized and their structures were determined.
ROLAND TELLGREN, JONAS HOWING, DUSAN SLADIC, ZIVOSLAV TESIC, MARIO ZLATOVIC, GORDANA JAKOVLJEVIC, KATARINA ANDELKOVIC   +6 more
doaj  

Health Literacy, Self‐Efficacy and Knowledge of Sickle Cell Disease Among Caregivers

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Sickle cell disease (SCD) is a hereditary blood disorder in which abnormal haemoglobin leads to severe anaemia, painful crises and organ failure. Caregivers’ health literacy (HL) – their ability to assess, understand and apply information, and interact with healthcare professionals – is crucial for managing children with SCD, yet ...
Melanie Bruinooge, Maite E. Houwing, Rowena L. Grohssteiner, Ferdows Atiq, Sonja A. M. C. Teuben, Mirjam P. Fransen, Marjon H. Cnossen   +6 more
wiley   +1 more source