Trametinib restores the central conducting lymphatic flow in a premature infant with Noonan syndrome
Key Clinical Message We describe a premature hydropic infant with Noonan syndrome and a therapy refractory chylothorax. This was shown to be due to a central conducting lymphatic anomaly. After therapy with a MEK‐inhibitor the infant recovered clinically
Willemijn M. Klein +11 more
core +1 more source
Amphibians: circulation: lymphatic hearts
Presents lymphatic hearts of amphibians at working and elucidate its function and anatomical relationsComponente Curricular::Educação Superior::Ciências Biológicas::Biologia GeralComponente Curricular::Educação Superior::Ciências Agrárias::Medicina ...
Sebben, Antonio
core
Amphibians: circulation: lymphatic hearts
Presents lymphatic hearts of amphibians at working and elucidate its function and anatomical relationsComponente Curricular::Educação Superior::Ciências Biológicas::Biologia GeralComponente Curricular::Educação Superior::Ciências Agrárias::Medicina ...
Sebben, Antonio
core
Peripheral and soft-tissue vascular malformations in the 2025 ISSVA classification: a practical MRI approach. [PDF]
Nagata S +6 more
europepmc +1 more source
Targeting PI3K/AKT/mTOR Pathway Exerts Inhibitory Effects on Endothelial Cells from Generalized Lymphatic Anomaly. [PDF]
Lorusso B +16 more
europepmc +1 more source
Interventional embolization for hemorrhagic pleural effusion in an infant with kaposiform lymphangiomatosis: a case report. [PDF]
Li J, Wang R, Liu C, Liu L.
europepmc +1 more source
Resolution of Refractory Chylous Effusions With Targeted MEK Inhibition in NRAS Q61R-Driven Kaposiform Lymphangiomatosis: A Case Report. [PDF]
Brown G +16 more
europepmc +1 more source
Long-term low-dose sirolimus therapy and successful discontinuation in an adult with kaposiform lymphangiomatosis and disseminated intravascular coagulation: a case report. [PDF]
Liu J, Xu W, Jiang Q, Xu KF.
europepmc +1 more source
Beyond Lesion Control: A Narrative Review of Targeted Therapy and Surgical Decision-Making in Children With Vascular Anomalies Across Function, Growth, and Perioperative Care. [PDF]
Altamimi O +10 more
europepmc +1 more source
Short-Term Efficacy and Safety of Topical Sirolimus Gel in Pediatric Superficial Microcystic Lymphatic Malformations: A Single-Center Interventional Study of 30 Patients. [PDF]
Xu W +6 more
europepmc +1 more source

