Results 111 to 120 of about 18,147,174 (321)

Analysis of echocardiographic parameters suggestive of pulmonary hypertension in patients with heart failure with preserved ejection fraction and assessment of clinical features favoring development of the PH-phenotype

Annales Academiae Medicae Silesiensis
Introduction: Heart failure with preserved ejection fraction (HFpEF) is characterized by left ventricle (LV) diastolic dysfunction. Impaired diastolic function induces pulmonary congestion and leads to postcapillary pulmonary hypertension (PH), which is ...
Julia Dołęga, Katarzyna Ciekot, Aleksandra Owczarska, Gabriela Majta, Michał Macnar, Klaudia Marcinkiewicz, Katarzyna Mizia-Stec   +6 more
doaj   +1 more source

Improving controllability of complex networks by rewiring links regularly

, 2014
Network science have constantly been in the focus of research for the last decade, with considerable advances in the controllability of their structural.
Jia, Siyuan, Wang, Jinfa, Xu, Jiuqiang, Zhao, Hai   +3 more
core   +1 more source

Valosin‐containing protein counteracts ATP‐driven dissolution of FUS condensates through its ATPase activity in vitro

FEBS Letters, EarlyView.
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura, Shin‐ichi Tate, Kyota Yasuda   +2 more
wiley   +1 more source

Spectral Scaling in Complex Networks

, 2005
A complex network is said to show topological isotropy if the topological structure around a particular node looks the same in all directions of the whole network. Topologically anisotropic networks are those where the local neighborhood around a node is
Estrada, Ernesto
core   +1 more source

Diversity and complexity in neural organoids

FEBS Letters, EarlyView.
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley   +1 more source

Weighted Visibility Graph With Complex Network Features in the Detection of Epilepsy

IEEE Access, 2016
Epilepsy detection from electrical characteristics of EEG signals obtained from the brain of undergone subject is a challenge task for both research and neurologist due to the non-stationary and chaotic nature of EEG signals.
Supriya, S. Siuly, Hua Wang, Jinli Cao, Yanchun Zhang   +4 more
semanticscholar   +1 more source

Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation

FEBS Letters, EarlyView.
Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz, Mihály Mérey, Rebeka Vásárhelyi, Ramóna Pék, Victor Imburchia, László Henn, Adrián Kószó, Nicholas D. Lakin, Ivan Ahel, Sébastien Huet, Ágnes Czibula, Gyula Timinszky   +11 more
wiley   +1 more source

Antioxidant Activity of γ-Oryzanol: A Complex Network of Interactions

International Journal of Molecular Sciences, 2016
γ-oryzanol (Orz), a steryl ferulate extracted from rice bran layer, exerts a wide spectrum of biological activities. In addition to its antioxidant activity, Orz is often associated with cholesterol-lowering, anti-inflammatory, anti-cancer and anti ...
I. Minatel, F. Francisqueti, C. Corrêa, G. Lima   +3 more
semanticscholar   +1 more source

Linking neurogenesis, oligodendrogenesis, and myelination defects to neurodevelopmental disruption in primary mitochondrial disorders

FEBS Letters, EarlyView.
Mitochondrial remodeling shapes neural and glial lineage progression by matching metabolic supply with demand. Elevated OXPHOS supports differentiation and myelin formation, while myelin compaction lowers mitochondrial dependence, revealing mitochondria as key drivers of developmental energy adaptation.
Sahitya Ranjan Biswas, Porter L. Tomsick, Alicia M. Pickrell, Paul D. Morton   +3 more
wiley   +1 more source

AAA+ protein unfoldases—the Moirai of the proteome

FEBS Letters, EarlyView.
AAA+ unfoldases are essential molecular motors that power protein degradation and disaggregation. This review integrates recent cryo‐electron microscopy (cryo‐EM) structures and single‐molecule biophysical data to reconcile competing models of substrate translocation.
Stavros Azinas, Marta Carroni
wiley   +1 more source