Results 111 to 120 of about 15,651,318 (279)

A Data-Driven Analysis for Understanding and Risk Estimation of Discolouration in Drinking Water Distribution Systems

Engineering Proceedings
This paper presents machine learning analysis to understand the factors impacting iron concentrations and discolouration customer contacts in drinking water distribution systems.
Grigorios Kyritsakas, Stewart Husband, Killian Gleeson, Katrina Flavell, Joby Boxall   +4 more
doaj   +1 more source

Spatial and single‐nuclei transcriptomics reveals idiosyncratic and generic patterns in papillary and anaplastic thyroid cancers

Molecular Oncology, EarlyView.
Matched spatial transcriptomics and single‐nuclei RNA‐seq were generated for anaplastic and BRAFV600E papillary thyroid cancers revealing generic and tumor‐specific states occurring in cancer cells and in the tumor microenvironment. In this context, cancer dedifferentiation mirrored organoid maturation through ordered thyroid marker gain/loss ...
Adrien Tourneur, Joel Rodrigues Vitória, Manuel Saiselet, Ligia Craciun, Denis Larsimont, Anne Lefort, Frédérick Libert, Carine Maenhaut, Sabine Costagliola, Maxime Tarabichi, Mirian Romitti, Vincent Detours   +11 more
wiley   +1 more source

From Simplistic to Complex Systems in Economics [PDF]

The applicability of complex systems theory in economics is evaluated and compared with standard approaches to economic theorizing based upon constrained optimization.
Prof John Foster
core  

In vitro and in silico modelling of ROS1‐positive non‐small cell lung cancer reveals fusion‐dependent tyrosine kinase inhibitor responses

Molecular Oncology, EarlyView.
Drug resistance limits treatment success in a subset of lung cancers driven by ROS1 gene alterations. Using patient‐derived cells and computer simulations, we studied three key mutations and how they affect five targeted drugs. The mutations reduced drug effectiveness in different ways by altering protein structure and behavior.
Farhan Ul Haq, Marc Terrones, Felicia Rodrigues Fortes, Anne Schepers, Alessia Denis, Christophe Deben, Ken Op de Beeck, Guy Van Camp, Geert Vandeweyer   +8 more
wiley   +1 more source

Complex Network Characteristic of Power System Based on Energy Information in the Steady Transition Process

, 2011
Abstracting the general concept of information andrelative state of element, based on the structure and state researchof complex network, this paper takes the branch potential energy asedge weight into the complex network modeling process of powersystem.
Jun Li, Jun-yong LIU, You-bo LIU, Li-min LIU   +3 more
core  

Circulating microRNA signatures of cachexia and cancer in Canis familiaris as a comparative oncology model for human disease

Molecular Oncology, EarlyView.
Circulating microRNAs as biomarkers of cachexia and sex‐specific cancer in senior dogs. In 25 client‐owned dogs, four circulating miRNAs (miR‐15a, miR‐15b, miR‐16, miR‐140) were downregulated in cachexia, with miR‐16 the strongest individual biomarker (AUC = 0.899).
Soon‐Seok Park, Kyongman An, Gyeonghwa Kim, Soo‐Nyun Choi, Hong‐Ki Lee, Keun Hur, Kyu‐Shik Jeong   +6 more
wiley   +1 more source

Actor Network Theory and adult education [PDF]

, 2015
The things and objects that help to enact and animate everyday work and learning practices are often ignored, dismissed or subordinated. Surfacing the materialities of practices is one appeal of theoretical perspectives such as Actor Network Theory (ANT).
Thompson, Terrie Lynn
core  

Causal Analysis and Prevention Strategies for Safety Risks in Prefabricated Building Construction Based on Accident Data and Complex Network Theory

Buildings
As China’s construction industry pays increasing attention to occupational health, prefabricated buildings, as an important direction for industry transformation, are gradually gaining widespread attention.
Wei Liu, Xiao Luo, Baojun Liang, Junhao Xie   +3 more
doaj   +1 more source

PANoptosis in the pathogenesis of myelodysplastic syndromes

Molecular Oncology, EarlyView.
PANoptosis, a combination of three types of programmed cell death, is mediated by a large protein complex called a PANoptosome. In healthy bone marrow hematopoietic cells, PANoptosis is restricted by inhibitory signaling. In MDS, bone marrow cells become sensitive to the PANoptotic stimuli due to the aberrant inactivation of inhibitory signaling or ...
Rohit Thalla, Jyoti Lamichhane, Cameron Lewis, Peter Breslin, Jiwang Zhang   +4 more
wiley   +1 more source

How can innovation economics benefit from complex network analysis? [PDF]

There is a deficit in economics of theories and empirical data on complex networks, though mathematicians, physicists, biologists, computer scientists, and sociologists are actively engaged in their study.
Brigitte GAY (LEREPS-GRES)
core