Results 81 to 90 of about 8,326,384 (290)

The Distribution of Complex Organic Molecules in the Orion KL Molecular Core [PDF]

open access: yes, 2011
We conducted high angular-resolution observations toward the massive star-forming region Orion KL at 1.3 mm using the Submillimeter Array (SMA). Spectral emission from twelve complex organic molecules was simultaneously imaged.
Charnley, Steven B.   +3 more
core  

Structures of mycobacterial 3‐methylcrotonyl‐CoA carboxylase reveal carrier‐domain translocation between catalytic sites

open access: yesFEBS Letters, EarlyView.
Mycobacterial 3‐methylcrotonyl‐CoA carboxylase uses a mobile biotin‐carrying domain to shuttle a carboxyl group between two catalytic sites, enabling carboxylation of 3‐methylcrotonyl‐CoA during leucine breakdown. Cryo‐electron microscopy captures the carrier at both sites and reveals an inward loop movement that may prevent futile rebinding to the ...
Ajit Yadav   +2 more
wiley   +1 more source

From junk to function — How weak selection in eukaryotes builds new parts and drives genomic complexity

open access: yesFEBS Letters, EarlyView.
How do genomes gain new functional parts? In eukaryotes, which tend to evolve under weak selection, much of the genome is junk. Palazzo and Qiu borrow the logic of Markov chains to show how non‐functional DNA becomes functional through the appearance of intermediate states, which arise due to epistasis, buffering, and biochemical messiness, allowing ...
Alexander F. Palazzo, Yi Qiu
wiley   +1 more source

Research Program for Organic Food and Farming in Finland [PDF]

open access: yes, 2005
The Finnish Ministry of Agriculture and Forestry started a three-year Research Programme on Organic Food and Farming in 2003. The programme consists of 15 projects on different themes covering the whole food chain and has an annual budget of about 2.2 ...
Nykaenen, Arja, Nykänen, Arja
core  

The Shewanella oneidensis Fic enzyme SoFic targets the switch‐I region of EF‐Tu for AMPylation

open access: yesFEBS Letters, EarlyView.
Fic enzymes mediate diverse post‐translational modifications across all domains of life, including AMPylation. Prokaryotic EF‐Tu can be AMPylated and deAMPylated by the conserved Fic enzyme SoFic. Structural and biochemical approaches were used to characterize the effect of AMPylation on EF‐Tu, SoFic's enzymatic activities, and the enzyme‐target ...
Svenja Runge   +6 more
wiley   +1 more source

One-dimensional and time-dependent modelling of complex organic molecules in protostars

open access: yesAstronomy & Astrophysics
Complex organic molecules (COMs), the building blocks of life, have been extensively detected under various physical conditions, from quiescent clouds to star-forming regions.
Tram Le Ngoc   +7 more
doaj   +1 more source

L‐aspartate oxidase provides new insights into fumarate reduction in anaerobic darkness in Synechocystis sp. PCC6803

open access: yesFEBS Letters, EarlyView.
Synechocystis strains deficient in succinate dehydrogenase (SDH) secrete more succinate than the WT under dark anaerobic conditions, supporting that SDH then primarily acts as SDH, not as a fumarate reductase. L‐aspartate oxidase (Laspo) from Synechocystis is functional under anaerobic conditions, reducing fumarate to succinate.
Kateryna Kukil   +3 more
wiley   +1 more source

Near-UV Spectrum of the Hexamethylenetetramine Cation

open access: yesThe Astrophysical Journal
Hexamethylenetetramine (HMT; (CH _2 ) _6 N _4 ) is a complex cage-like molecule that forms by the reaction of ammonia with formaldehyde, two of the most prevalent components of ice mantles on interstellar dust grains.
Parker Crandall   +3 more
doaj   +1 more source

Organic material in meteorites and the link to the origin of life

open access: yesBIO Web of Conferences, 2014
Life requires specific conditions that have been, so far, only proven to meet on Earth. Though the chemical elements required to form living organism (C, H, N, O, S, etc) are widespread in the universe, the molecules that are crucial for Life, like ...
Remusat L.
doaj   +1 more source

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