Results 81 to 90 of about 767,104 (296)
Investigating the Efficiency of Explosion Chemistry as a Source of Complex Organic Molecules in TMC-1 [PDF]
, 2019 Many species of complex organic molecules (COMs) have been observed in several astrophysical environments but it is not clear how they are produced, particularly in cold, quiescent regions.
Balucani, Nadia +5 more
core +2 more sources
FEBS Letters, EarlyView.We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley +1 more source
Near-UV Spectrum of the Hexamethylenetetramine Cation
The Astrophysical JournalHexamethylenetetramine (HMT; (CH _2 ) _6 N _4 ) is a complex cage-like molecule that forms by the reaction of ammonia with formaldehyde, two of the most prevalent components of ice mantles on interstellar dust grains.
Parker Crandall +3 more
doaj +1 more source
Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
FEBS Letters, EarlyView.Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley +1 more source
FEBS Letters, EarlyView.This study reveals a unique active site enriched in methionine residues and demonstrates that these residues play a critical role by stabilizing carbocation intermediates through novel sulfur–cation interactions. Structure‐guided mutagenesis further revealed variants with significantly altered product profiles, enhancing pseudopterosin formation. These
Marion Ringel +13 more
wiley +1 more source
Digging into the Chemical Complexity in the Outer Galaxy: A Hot Molecular Core in Sh 2-283
The Astrophysical JournalThe outer Galaxy (Galactocentric distance ≳13.5 kpc) serves as an excellent laboratory for investigating the chemical complexity in low-metallicity environments.
Toki Ikeda +5 more
doaj +1 more source
Bis(2-methoxybenzylammonium) diaquabis(dihydrogen diphosphato-κ2O,O′)cobaltate(II) dihydrate
Acta Crystallographica Section E, 2014 The title compound, (C8H12NO)2[Co(H2P2O7)2(H2O)2]·2H2O, crystallizes isotypically with its MnII analogue. It consists of alternating layers of organic cations and inorganic complex anions, extending parallel to (100).
Adel Elboulali +4 more
doaj +1 more source
Diversity and complexity in neural organoids
FEBS Letters, EarlyView.Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley +1 more source
Carbon Isotope Fractionation of Complex Organic Molecules in Star-forming Cores
The Astrophysical JournalRecent high-resolution and sensitivity Atacama Large Millimeter/submillimeter Array observations have unveiled the carbon isotope ratios ( ^12 C/ ^13 C) of complex organic molecules (COMs) in a low-mass protostellar source. To understand the ^12 C/ ^13 C
Ryota Ichimura +2 more
doaj +1 more source
Organic Molecules in the Icy Bodies of Planetary Systems – Accepted Notions and New Ideas
Open Astronomy, 2018 Cometary bodies are acknowledged to contain some of the most pristine matter in the Solar System, including ices and minerals. Certain number of previously unidentified spectral emission features detected in comets can be explained as emission by ...
Simonia Irakli, Cruikshank Dale P.
doaj +1 more source