Synthetic strategies for complex molecules in organic chemistry
Within this thesis, three synthetic procedures are discussed. Here different approaches were pursued to synthesize complex molecules. In the first chapter, an oxidative method is described to achieve C–C bond cleavage and thus target the transformations of the backbone structure of a molecule leading to late-stage manipulations.
openaire +2 more sources
Artificial molecular machines and motors—Design and control of nanoscale motion
Molecules are constantly moving because of thermal fluctuations, but random motion alone cannot be exploited to perform directional tasks. Artificial molecular machines use chemical, electrical, or light energy to bias this motion. Molecular shuttles, rotary motors, and supramolecular pumps illustrate how nanoscale movement can be controlled and ...
Leonardo Andreoni, Alberto Credi
wiley +1 more source
Ordering of organic molecules on templated surfaces [PDF]
This thesis describes the controlled growth of molecular nanostructures using modified metallic and semiconductor surfaces. The Ag/Si(lll)-(root3 x root3),the Sn/Cu(100) surface alloy system and the Bi/Si(100) nanolines and (2xn) surfaces were all ...
Sheerin, Grainne
core +2 more sources
Heterodimeric amino acid transporters consist of SLC7 and SLC3 family proteins arranged in a conserved structural organization. They regulate nutrient transport across cell membranes, supporting essential cellular functions. These transporters also contribute to xenobiotic/drug uptake and distribution.
Mariafrancesca Scalise +5 more
wiley +1 more source
Digging into the Chemical Complexity in the Outer Galaxy: A Hot Molecular Core in Sh 2-283
The outer Galaxy (Galactocentric distance ≳13.5 kpc) serves as an excellent laboratory for investigating the chemical complexity in low-metallicity environments.
Toki Ikeda +5 more
doaj +1 more source
O-bearing complex organic molecules at the cyanopolyyne peak of TMC-1: detection of C<sub>2</sub>H<sub>3</sub>CHO, C<sub>2</sub>H<sub>3</sub>OH, HCOOCH<sub>3</sub>, and CH<sub>3</sub>OCH<sub>3</sub>. [PDF]
Agúndez M +5 more
europepmc +1 more source
The ubiquitin system in normal and infected germinal center B cells
The ubiquitin system plays a central role in germinal center (GC) B cells, influencing differentiation to long‐lived memory B cells. Oncogenic gammaherpesviruses gain access to memory B cells by establishing latency in GC B cells. Mapping ubiquitin mechanisms in normal and infected GC B cells will define specific molecular circuits in B cells germane ...
Destiny Davis +2 more
wiley +1 more source
Electrochemical Assembly for Synthesis of Middle-Sized Organic Molecules [PDF]
Electrochemical methods offer a powerful, reliable, and environmentally benign approach for the synthesis of small organic molecules, and such methods are useful not only for the transformation of small molecules, but also for the preparation of ...
26443 +7 more
core +1 more source
Carbon Isotope Fractionation of Complex Organic Molecules in Star-forming Cores
Recent high-resolution and sensitivity Atacama Large Millimeter/submillimeter Array observations have unveiled the carbon isotope ratios ( ^12 C/ ^13 C) of complex organic molecules (COMs) in a low-mass protostellar source. To understand the ^12 C/ ^13 C
Ryota Ichimura +2 more
doaj +1 more source
Metastatic niche shaped by host factors influences disseminated cancer cell fate
Metastasis is shaped not only by cancer cells but also by the environments they encounter. This review explores how factors such as aging, diet, the microbiome, lifestyle, and environmental exposures remodel organ‐specific niches in the lung, liver, bone, and brain, influencing where metastatic cells survive, remain dormant, or grow, and ultimately ...
Gwennan Delyth Ward +2 more
wiley +1 more source

