Results 101 to 110 of about 767,104 (296)

Gas-Phase vs. Grain-Surface Formation of Interstellar Complex Organic Molecules: A Comprehensive Quantum-Chemical Study. [PDF]

Int J Mol Sci, 2023
Martínez-Bachs B, Rimola A.
europepmc   +1 more source

From Prestellar to Protostellar Cores II. Time Dependence and Deuterium Fractionation

, 2012
We investigate the molecular evolution and D/H abundance ratios that develop as star formation proceeds from a dense-cloud core to a protostellar core, by solving a gas-grain reaction network applied to a 1-D radiative hydrodynamic model with infalling ...
Aikawa, Yuri, Garrod, Robin T., Herbst, Eric, Hersant, Franck, Wakelam, Valentine   +4 more
core   +3 more sources

LDAcoop: Integrating non‐linear population dynamics into the analysis of clonogenic growth in vitro

Molecular Oncology, EarlyView.
Limiting dilution assays (LDAs) quantify clonogenic growth by seeding serial dilutions of cells and scoring wells for colony formation. The fraction of negative wells is plotted against cells seeded and analyzed using the non‐linear modeling of LDAcoop.
Nikko Brix, Daniel Samaga, Katharina Gehr, Benedek Dankó, Mohamed Schumann, Guido Drexler, Ahmed Alnatsha, Georg Beyer, Ujjwal Mahajan, Martin Selmansberger, Julia Mayerle, Claus Belka, Horst Zitzelsberger, Kirsten Lauber   +13 more
wiley   +1 more source

Methyl Isocyanate Formation from Oxygen Insertion in Methyl Cyanide Ices

The Astrophysical Journal
In cold molecular clouds, UV photolysis of icy grain mantles generates radicals that lead to new molecule formation. When radical diffusion is limited by low temperatures, oxygen atom addition and insertion reactions, enabled by photolysis of common ice ...
Michelle R. Brann, Mahesh Rajappan, Karin I. Öberg   +2 more
doaj   +1 more source

Dammarenediol II enhances etoposide‐induced apoptosis by targeting O‐GlcNAc transferase and Akt/GSK3β/mTOR signaling in liver cancer

Molecular Oncology, EarlyView.
Etoposide induces DNA damage, activating p53‐dependent apoptosis via caspase‐3/7, which cleaves PARP1. Dammarenediol II enhances this apoptotic pathway by suppressing O‐GlcNAc transferase activity, further decreasing O‐GlcNAcylation. The reduction in O‐GlcNAc levels boosts p53‐driven apoptosis and influences the Akt/GSK3β/mTOR signaling pathway ...
Jaehoon Lee, Byung‐Cheol Han, Gi‐Bang Koo, Jihye Park, Mijin Kwon, Young Bin Park, Jae‐Mun Choi, Seung‐Ho Lee, Sangho Roh   +8 more
wiley   +1 more source

The Cell and the Sum of Its Parts: Patterns of Complexity in Biosignatures as Revealed by Deep UV Raman Spectroscopy

Frontiers in Microbiology, 2019
The next NASA-led Mars mission (Mars 2020) will carry a suite of instrumentation dedicated to investigating Martian history and the in situ detection of potential biosignatures. SHERLOC, a deep UV Raman/Fluorescence spectrometer has the ability to detect
Haley M. Sapers, Haley M. Sapers, Haley M. Sapers, Joseph Razzell Hollis, Rohit Bhartia, Luther W. Beegle, Victoria J. Orphan, Jan P. Amend, Jan P. Amend   +8 more
doaj   +1 more source

Tumor mutational burden as a determinant of metastatic dissemination patterns

Molecular Oncology, EarlyView.
This study performed a comprehensive analysis of genomic data to elucidate whether metastasis in certain organs share genetic characteristics regardless of cancer type. No robust mutational patterns were identified across different metastatic locations and cancer types.
Eduardo Candeal, Andrea Moreno‐Manuel, Miguel Salvadó‐Pertierra, Cristina Santos‐Vivas, Rebeca Sanz‐Pamplona   +4 more
wiley   +1 more source

ALMA Spectral Survey of an Eruptive Young Star, V883 Ori (ASSAY). II. Freshly Sublimated Complex Organic Molecules in the Keplerian Disk

The Astrophysical Journal Supplement Series
We present an investigation of complex organic molecules (COMs) in the spatially resolved Keplerian disk around V883 Ori, an eruptive young star, based on a spectral survey carried out with the Atacama Large Millimeter/submillimeter Array in Band 6 (220 ...
Jae-Hong Jeong, Jeong-Eun Lee, Seonjae Lee, Giseon Baek, Ji-Hyun Kang, Seokho Lee, Chul-Hwan Kim, Hyeong-Sik Yun, Yuri Aikawa, Gregory J. Herczeg, Doug Johnstone, Lucas Cieza   +11 more
doaj   +1 more source

O-bearing complex organic molecules at the cyanopolyyne peak of TMC-1: detection of C₂H₃CHO, C₂H₃OH, HCOOCH₃, and CH₃OCH₃. [PDF]

Astron Astrophys, 2021
Agúndez M, Marcelino N, Tercero B, Cabezas C, de Vicente P, Cernicharo J.   +5 more
europepmc   +1 more source

Production and condensation of organic gases in the atmosphere of Titan [PDF]

The rates and altitudes for the dissociation of atmospheric constituents on Titan are calculated for solar ultraviolet radiation, the solar wind, Saturn magnetospheric particles, the Saturn co-rotating plasma, and cosmic rays. Laboratory experiments show
Sagan, C., Thompson, W. R.
core   +1 more source