Results 181 to 190 of about 2,361,537 (287)

RaMBat: Accurate identification of medulloblastoma subtypes from diverse data sources with severe batch effects

Molecular Oncology, EarlyView.
To integrate multiple transcriptomics data with severe batch effects for identifying MB subtypes, we developed a novel and accurate computational method named RaMBat, which leveraged subtype‐specific gene expression ranking information instead of absolute gene expression levels to address batch effects of diverse data sources.
Mengtao Sun, Jieqiong Wang, Shibiao Wan
wiley   +1 more source

Correction: An axiomatic system engineering design method based on NSGA-II algorithm applied to complex systems. [PDF]

Sci Rep
Zhang X, Zhang Q, Zhao Q, Zhao S, Zhao Y, Guo Y, Zhao Z, Song L.   +7 more
europepmc   +1 more source

The Genesis of Innovation Space: Multi-Phase Aggregation and the Emergence of a Complex System

Zhao, Fan
openalex   +1 more source

Identification of serum protein biomarkers for pre‐cancerous lesions associated with pancreatic ductal adenocarcinoma

Molecular Oncology, EarlyView.
This work identified serum proteins associated with pancreatic epithelial neoplasms (PanINs) and early‐stage PDAC. Proteomics screens assessed genetically engineered mice with abundant PanINs, KPC mice (Lox‐STOP‐Lox‐KrasG12D/+ Lox‐STOP‐Lox‐Trp53R172H/+ Pdx1‐Cre) before PDAC development and also early‐stage PDAC patients (n = 31), compared to benign ...
Hannah Mearns, Jaclyn S. Long, Sergio Lilla, Kelly Hodge, Marcus J. G. W. Ladds, Colin Nixon, Paula Fernández‐Palanca, Sara Zanivan, Pilar Acedo, Stephen P. Pereira, Kevin M. Ryan   +10 more
wiley   +1 more source

The topology of synergy: Linking topological and information-theoretic approaches to higher-order interactions in complex systems. [PDF]

PLoS Comput Biol
Varley TF, Mediano PAM, Patania A, Bongard J.   +3 more
europepmc   +1 more source

Open source workflow systems for the development of complex computational experiments

, 2012
Κλειώ Αχιλλέως, K. G. Achilleos   +1 more
openalex   +1 more source

A Unified Metric for Modeling Coherence, Entropy Compensation and Pattern Stability in Complex Systems

Garbar, Iryna
openalex   +1 more source

An Efficient Simulation Method for Determining the Density of States of Complex Systems [PDF]

, 2019
Takuya Hayashi, Yuko Okamoto
openalex  

Complex systems [PDF]

Nature, 1977
openaire   +1 more source

Subtype‐specific enhancer RNAs define transcriptional regulators and prognosis in breast cancers

Molecular Oncology, EarlyView.
This study employed machine learning methodologies to perform the subtype‐specific classification of RNA‐seq data sets, which are mapped on enhancers from TCGA‐derived breast cancer patients. Their integration with gene expression (referred to as ProxCReAM eRNAs) and chromatin accessibility profiles has the potential to identify lineage‐specific and ...
Aamena Y. Patel, Peyman Zarrineh, Nathnael T. Tuffa, Jigar H. Sheth, Sumitra Mohan, Mudassar Iqbal, Sankari Nagarajan   +6 more
wiley   +1 more source