Results 111 to 120 of about 7,641,584 (361)

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

FEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

Conjugates of methylated cyclodextrin derivatives and hydroxyethyl starch (HES): Synthesis, cytotoxicity and inclusion of anaesthetic actives

Beilstein Journal of Organic Chemistry, 2014
The mono-6-deoxy-6-azides of 2,6-di-O-methyl-β-cyclodextrin (DIMEB) and randomly methylated-β-cyclodextrin (RAMEB) were conjugated to propargylated hydroxyethyl starch (HES) by Cu+-catalysed [2 + 3] cycloaddition.
Lisa Markenstein, Antje Appelt-Menzel, Marco Metzger, Gerhard Wenz   +3 more
doaj   +1 more source

Recent developments in surface complexation modeling [PDF]

, 2014
Editorial to special section on surface complexation modeling containing papers presented during the session “Recent developments in surface complexation modelling: trace element speciation and reactive transport modelling” at the 12th International ...
Groenenberg, Jan E., Jan E. Groenenberg, Stephen Lofts, Groenenberg, J.E., Lofts, S., Lofts, Stephen   +5 more
core   +1 more source

Effect of cyclodextrin complexation on phenylpropanoids’ solubility and antioxidant activity

Beilstein Journal of Organic Chemistry, 2014
The complexation abilities of five cyclodextrins (CDs) with seven phenylpropanoids (PPs) were evaluated by UV–visible spectroscopy, phase solubility studies and molecular modeling. Formation constants (Kf), complexation efficiency (CE), PP:CD molar ratio,
Miriana Kfoury, D. Landy, L. Auezova, H. Greige‐Gerges, S. Fourmentin   +4 more
semanticscholar   +1 more source

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

FEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai, Mizuki Seo, Gyath Karadsheh, Fachrur Rizal Mahendra, Máté Á Demény, Ferenc Győry, János András Mótyán, László Fésüs, Endre Kristóf, Rini Arianti   +9 more
wiley   +1 more source

Study on Adsorption and Complexation Behavior of Thiourea on Copper Surface

International Journal of Electrochemical Science, 2011
The reaction behaviors of various concentrations of thiourea (TU) on copper surface in 0.5 mol/L H2SO4 solution were investigated by electrochemical methods and single crystallogram. Weak interaction occurs at low concentration of TU.
Jie Zhao, Guofeng Cui
doaj   +1 more source

Copper isotope fractionation during complexation with insolubilized humic acid

, 2010
The bioavailability, mobility, and toxicity of Cu depend on Cu speciation in solution. In natural systems like soils, sediments, lakes, and river waters, organo-Cu complexes are the dominating species.
Weyer, Stefan, Wilcke, Wolfgang, Bigalke, Moritz, Wolfgang Wilcke, Stefan Weyer, Moritz Bigalke   +5 more
core   +1 more source

The planar cell polarity protein Vangl2 interacts with the PDZ‐domains of Scribble but not with a unique PDZ‐like domain in Inturned

FEBS Letters, EarlyView.
Structural and biochemical characterisations show that the planar cell polarity (PCP) protein Inturned harbours a unique PDZ‐like domain that does not bind canonical PDZ‐binding motifs (PBMs) like that of another PCP protein Vangl2. In contrast, the apical‐basal polarity protein Scribble contains four PDZ domains that bind Vangl2, but one PDZ domain ...
Stephan Wilmes, Jan Brysch, Carmen Gelze, Lilli Meier, Daniel Kümmel   +4 more
wiley   +1 more source

Behaviour of cerium (III) phosphate in a carbonate-alkaline medium

Записки Горного института
The article investigates the behaviour of rare earth metals in carbonate-alkaline systems. The results of experimental studies on rare earth element extraction from phosphogypsum, a large-tonnage industrial waste forming in production of phosphoric acid ...
Tatyana E. Litvinova, Stepan A. Gerasev
doaj  

Tau acetylation at K331 has limited impact on tau pathology in vivo

FEBS Letters, EarlyView.
We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto, Yukio Matsuba, Mika Takahashi, Takaomi C. Saido   +3 more
wiley   +1 more source