Results 121 to 130 of about 131,850 (307)
Liver organoids: modelling complexity in homeostasis and disease
FEBS Letters, EarlyView.Studying liver in vitro has been challenging because simple 2D cell cultures fail to capture liver's cellular and architectural complexity. To bridge this gap, scientists increasingly use organoids, 3D liver models which better mimic liver composition and function. This review examines recent advances in liver organoid complexity and realism, discusses
Anna M. Dowbaj, Meritxell Huch
wiley +1 more source
The microbiome in human skin aging
FEBS Letters, EarlyView.Age‐related skin changes encompass the well‐known visible phenotypic alterations, together with microbiome dysbiosis and a series of molecular aging hallmarks. These hallmarks characterize not only a fully stablished aged phenotype but also the skin aging process itself.
Manuel Huerta Arana +3 more
wiley +1 more source
Effect of HSA complexation on drug released from nanoparticles.
, 2013 Effect of HSA complexation on drug released from nanoparticles.
Wenzhi Yang (298905) +6 more
core +1 more source
Complexation of uranium(VI) with acetate at variable temperatures
, 2002 The complexation between uranium(VI) and acetate in 1.05 mol kg_1 NaClO4 was studied at variable temperatures (25, 35, 45, 55 and 70 °C). The formation constants of three successive complexes, UO2(OOCCH3)_, UO2 (OOCCH3)2 and UO2(OOCCH3)3 , and the ...
Jiang J +4 more
core +2 more sources
FEBS Letters, EarlyView.This review focuses on the role of autophagy and mitophagy in maintaining pancreatic β‐cell function and homeostasis. We discuss how genetic defects affecting these pathways contribute to the development of type 1, type 2, monogenic, and gestational diabetes. We further explore their potential as therapeutic targets. Created in BioRender.
Yunkyeong Lee +2 more
wiley +1 more source
Voltammetric Characterization of Cu(II) Complexation in Real-Time
, 2016 Aqueous metal behavior is strongly regulated by speciation, which in turn is highly dependent on complexation. Trace metal complexation is difficult to characterize in dynamically changing systems due to a lack of analytical methods that can rapidly ...
Shawn P. McElmurry (2057140) +5 more
core +1 more source
FEBS Letters, EarlyView.Obesity raises blood levels of PAI‐1, a protein linked to metabolic dysfunction‐associated steatotic liver disease in people with obesity. In female mice fed a high‐fat diet, partially lowering PAI‐1 led to smaller subcutaneous fat cells and lower liver cholesterol, without changing body weight or insulin sensitivity.
Claudia E. Ramirez Bustamante +10 more
wiley +1 more source
Chitosan-Polyphosphate Complexation for Fabrication of Advanced Functional Biomaterials
This thesis investigates the complexation between Chitosan (CS) and Polyphosphate (PP) for advanced biomedical applications, including drug delivery and hemostasis.
Fanaee, Sajjad
core
Complexation of Arsenite with Humic Acid in the Presence of Ferric Iron
, 2016 In the presence of iron (Fe), dissolved organic matter (DOM) may bind considerable amounts of arsenic (As), through formation of Fe-bridged As−Fe-DOM complexes and surface complexation of As on DOM-stabilized Fe-colloids (collectively referred to as As ...
Yong Cai (292486) +2 more
core +1 more source
Ligand‐dependent transcriptional heterogeneity in cell cycle gene expression delays G1/S entry
FEBS Letters, EarlyView.EGF and HRG induce distinct G1/S progression programs in ErbB2‐amplified BT474 breast cancer cells. Despite activating the potent ErbB2–ErbB3 heterodimer, HRG does not accelerate cell‐cycle entry. Instead, EGF promotes earlier restriction‐point passage via ERK–FOS signaling, whereas HRG activates the AKT–MYC axis, driving transcriptional heterogeneity ...
Ririn Rahmala Febri +5 more
wiley +1 more source