Results 51 to 60 of about 7,641,584 (361)

Energetic competition in the complexation affinity of paracetamol with water and oxalic acid

, 2022
The intermolecular interactions of active pharmaceutical ingredients (APIs) are the driving forces of API molecular activity and stability, in vivo receptor binding, environmental transport, and persistence.
Valenzano-Slough, Loredana, Amanda Studinger (14179206), Loredana Valenzano-Slough (14179209), Studinger, Amanda, Amanda, Studinger, Loredana, Valenzano-Slough   +5 more
core   +1 more source

Venous Thromboembolism in Pediatric Bone Sarcoma Patients: A 10‐Year, Single‐Institution Experience Encompassing the COVID‐19 Pandemic

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Osteosarcoma (OS) and Ewing sarcoma (EWS) are the most common primary bone cancers in children, but acute thrombosis is poorly characterized in this population. Our study evaluated the rates of venous thromboembolism (VTE) and associated risk factors in pediatric patients with bone sarcomas treated over a 10‐year period encompassing
Sarah Kappa, Shou Xu, Mark Zobeck, Sarah E. Sartain, Nino Rainusso, Lisa Wang, Nicole Montgomery, Paige Wheaton, Sarah Whittle   +8 more
wiley   +1 more source

Competition from Cu(II), Zn(II) and Cd(II) in Pb(II) binding to Suwannee River Fulvic Acid

, 2008
This is a study of trace metal competition in the complexation of Pb(II) by well-characterized humic substances, namely Suwannee River Fulvic Acid (SRFA) in model solutions.
Chakrabarti, C.L., Chakraborty, P.
core   +1 more source

Claudin‐6 Protein Expression in Atypical Teratoid/Rhabdoid Tumors Is Strongly Enriched in the Molecular Subgroup AT/RT‐TYR

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Claudin‐6 has emerged as a promising immunotherapeutic target, yet protein‐level data in atypical teratoid/rhabdoid tumors (AT/RTs) have been inconsistent. We analyzed 36 well‐characterized AT/RT samples and found membranous claudin‐6 protein expression in 58% of cases, with striking enrichment in the molecular subgroup AT/RT‐TYR (100%) and ...
Victoria E. Fincke, Christian Thomas, Michael C. Frühwald, Pascal D. Johann, Martin Hasselblatt   +4 more
wiley   +1 more source

The Effect of Composition of Different Ecotoxicological Test Media on Free and Bioavailable Copper from CuSO4 and CuO Nanoparticles: Comparative Evidence from a Cu-Selective Electrode and a Cu-Biosensor

Sensors, 2011
The analysis of (bio)available copper in complex environmental settings, including biological test media, is a challenging task. In this study, we demonstrated the potential of a recombinant Pseudomonas fluorescens-based biosensor for bioavailability ...
Angela Ivask, Olesja Bondarenko, Anne Kahru, Aleksandr Käkinen   +3 more
doaj   +1 more source

Development and application of an assay for uranyl complexation by fungal metabolites, including siderophores

, 2003
An assay to detect UO2 2+ complexation was developed based on the chrome azurol S (CAS) assay for siderophores (B. Schwyn and J. B. Neilands, Anal. Biochem.
Trinci, A.P.J., Robson, GD, Livens, F.R., Livens, Francis R., Collison, D., Renshaw, Joanna, Robson, G.D., Halliday, Verity, Collison, David, Wiebe, Marilyn G., Livens, FR, Renshaw, Joanna C., Collison, D, Wiebe, Marilyn, Halliday, V, Taylor, RJ, Robson, Geoffrey D., Wiebe, MG, Trinci, Anthony P J, Renshaw, J.C., Taylor, R.J., Trinci, APJ, Taylor, Robin J., Halliday, V.   +23 more
core   +1 more source

Time Toxicity in Wilms Tumor: Quantifying the Burden of Healthcare Interaction in the First Year After Diagnosis

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Wilms tumor (WT) treatment imposes a significant time burden on patients and their families. Time toxicity is a patient‐centered metric that quantifies the burden of healthcare interaction. We sought to define time toxicity in the first year after diagnosis of WT and hypothesized that it would increase as tumor stage and treatment ...
Caleb Q. Ashbrook, Veerain Gupta, Nicholas J. Clark, Vijay Rings, Lauren E. Corona, Douglass B. Clayton, Daniel J. Benedetti   +6 more
wiley   +1 more source

Complex Complexes: Signaling at the TCR [PDF]

Immunity, 1996
The focus of this review has been on the complexity of biochemical events at a very proximal position in the TCR signaling cascade. A number of proteins and protein–protein interactions have been described. It should be noted that the function of many of these proteins (e.g., Vav, Cbl, PI3K, and SLP-76) remains to be defined.
Wange, Ronald L, Samelson, Lawrence E
openaire   +2 more sources

Geochemical Controls on Release and Speciation of Fe(II) and Mn(II) From Hyporheic Sediments of East River, Colorado

Frontiers in Water, 2020
Hyporheic zones act as critical ecological links between terrestrial and aquatic systems where redox-sensitive metals of iron (Fe) and manganese (Mn) significantly impact nutrient cycling and water quality.
Wenming Dong, Amrita Bhattacharyya, Patricia M. Fox, Markus Bill, Dipankar Dwivedi, Sergio Carrero, Mark Conrad, Peter S. Nico   +7 more
doaj   +1 more source

Increased Risk of Sarcomas in Children With Congenital Anomalies: Findings From the Genetic Overlap Between Anomalies and Cancer in Kids (GOBACK) Registry Linkage Study

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Pediatric sarcomas are a heterogeneous group of tumors that contribute disproportionately to cancer mortality in children. Although congenital anomalies are among the strongest known risk factors for childhood cancer, the risk of specific sarcoma subtypes among affected individuals has not yet been thoroughly evaluated. Procedure We
Russ Wolters, Ji Yun Tark, Tiffany M. Chambers, Tania A. Desrosiers, Michael E. Scheurer, Charles Shumate, Wendy N. Nembhard, Mahsa M. Yazdy, Eirini Nestoridi, Amanda E. Janitz, Jean Paul Tanner, Russell S. Kirby, Jason L. Salemi, Yao Yu, Chad D. Huff, Sharon E. Plon, Philip J. Lupo, Jeremy M. Schraw   +17 more
wiley   +1 more source