Results 41 to 50 of about 7,748,503 (383)

Fungal-bacterial diversity and microbiome complexity predict ecosystem functioning

open access: yesNature Communications, 2019
The soil microbiome is highly diverse and comprises up to one quarter of Earth’s diversity. Yet, how such a diverse and functionally complex microbiome influences ecosystem functioning remains unclear.
Cameron Wagg   +4 more
semanticscholar   +1 more source

Biophysical analysis of angiotensin II and amyloid‐β cross‐interaction in aggregation and membrane disruption

open access: yesFEBS Letters, EarlyView.
Angiotensin II (AngII), a neuropeptide, interacts with amyloid‐β (Aβ), a key player in Alzheimer's disease. This study reveals that AngII reduces Aβ aggregation and membrane disruption in vitro. Biophysical assays and molecular modeling suggest AngII binds disordered Aβ forms, potentially modulating early amyloidogenic events and contributing to ...
Mohsen Habibnia   +5 more
wiley   +1 more source

Inequality in economic shock exposures across the global firm-level supply network

open access: yesNature Communications
For centuries, national economies have been engaging in international trade and production. The resulting international supply networks not only increase wealth for countries, but also allow for economic shocks to propagate across borders.
Abhijit Chakraborty   +4 more
doaj   +1 more source

Quantum Hamiltonian Complexity

open access: yes, 2015
Constraint satisfaction problems are a central pillar of modern computational complexity theory. This survey provides an introduction to the rapidly growing field of Quantum Hamiltonian Complexity, which includes the study of quantum constraint ...
Gharibian, Sevag   +3 more
core   +1 more source

4‐nitrobenzoate inhibits 4‐hydroxybenzoate polyprenyltransferase in malaria parasites and enhances atovaquone efficacy

open access: yesFEBS Letters, EarlyView.
Atovaquone is an antimalarial requiring potentiation for sufficient efficacy. We pursued strategies to enhance its activity, showing that 4‐nitrobenzoate inhibits 4‐hydroxybenzoate polyprenyltransferase, decreasing ubiquinone biosynthesis. Since atovaquone competes with ubiquinol in mitochondria, 4‐nitrobenzoate facilitates its action, potentiating ...
Ignasi Bofill Verdaguer   +7 more
wiley   +1 more source

Quantifying the stability of refugee populations: a case study in Austria

open access: yesGenus
The global surge in displacement, with nearly 110 million people uprooted due to violence, underscores the pressing need to comprehend the challenges faced by refugees. Population growth, environmental crises, and political instability contribute to this
Ola Ali   +4 more
doaj   +1 more source

Binary Determinantal Complexity

open access: yes, 2015
We prove that for writing the 3 by 3 permanent polynomial as a determinant of a matrix consisting only of zeros, ones, and variables as entries, a 7 by 7 matrix is required.
Hüttenhain, Jesko, Ikenmeyer, Christian
core   +1 more source

Linked dimers of the AAA+ ATPase Msp1 reveal energetic demands and mechanistic plasticity for substrate extraction from lipid bilayers

open access: yesFEBS Letters, EarlyView.
Cells must clear mislocalized or faulty proteins from membranes to survive. The AAA+ ATPase Msp1 performs this task, but dissecting how its six subunits work together is challenging. We engineered linked dimers with varied numbers of functional subunits to reveal how Msp1 subunits cooperate and use energy to extract proteins from the lipid bilayer ...
Deepika Gaur   +5 more
wiley   +1 more source

Infinite Communication Complexity [PDF]

open access: yes, 2014
Suppose that Alice and Bob are given each an infinite string, and they want to decide whether their two strings are in a given relation. How much communication do they need? How can communication be even defined and measured for infinite strings? In this
Guillon, Pierre, Jeandel, Emmanuel
core   +3 more sources

Organoids in pediatric cancer research

open access: yesFEBS Letters, EarlyView.
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley   +1 more source

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