Results 41 to 50 of about 6,001,676 (290)
FEBS Letters, EarlyView.Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho +3 more
wiley +1 more source
Infinite Communication Complexity [PDF]
, 2014 Suppose that Alice and Bob are given each an infinite string, and they want to decide whether their two strings are in a given relation. How much communication do they need? How can communication be even defined and measured for infinite strings? In this
Guillon, Pierre, Jeandel, Emmanuel
core +3 more sources
By dawn or dusk—how circadian timing rewrites bacterial infection outcomes
FEBS Letters, EarlyView.The circadian clock shapes immune function, yet its influence on infection outcomes is only beginning to be understood. This review highlights how circadian timing alters host responses to the bacterial pathogens Salmonella enterica, Listeria monocytogenes, and Streptococcus pneumoniae revealing that the effectiveness of immune defense depends not only
Devons Mo +2 more
wiley +1 more source
Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?
FEBS Letters, EarlyView.This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes +3 more
wiley +1 more source
The role and implications of mammalian cellular circadian entrainment
FEBS Letters, EarlyView.At their most fundamental level, mammalian circadian rhythms occur inside every individual cell. To tell the correct time, cells must align (or ‘entrain’) their circadian rhythm to the external environment. In this review, we highlight how cells entrain to the major circadian cues of light, feeding and temperature, and the implications this has for our
Priya Crosby
wiley +1 more source
Quantum Certificate Complexity [PDF]
, 2002 Given a Boolean function f, we study two natural generalizations of the certificate complexity C(f): the randomized certificate complexity RC(f) and the quantum certificate complexity QC(f). Using Ambainis' adversary method, we exactly characterize QC(f)
Aaronson, Scott
core +6 more sources
Binary Determinantal Complexity
, 2015 We prove that for writing the 3 by 3 permanent polynomial as a determinant of a matrix consisting only of zeros, ones, and variables as entries, a 7 by 7 matrix is required.
Hüttenhain, Jesko, Ikenmeyer, Christian
core +1 more source
Descriptive Complexity for counting complexity classes [PDF]
2017 32nd Annual ACM/IEEE Symposium on Logic in Computer Science (LICS), 2017 Descriptive Complexity has been very successful in characterizing complexity classes of decision problems in terms of the properties definable in some logics. However, descriptive complexity for counting complexity classes, such as FP and #P, has not been systematically studied, and it is not as developed as its decision counterpart.
Marcelo Arenas +2 more
openaire +5 more sources
Molecular bases of circadian magnesium rhythms across eukaryotes
FEBS Letters, EarlyView.Circadian rhythms in intracellular [Mg2+] exist across eukaryotic kingdoms. Central roles for Mg2+ in metabolism suggest that Mg2+ rhythms could regulate daily cellular energy and metabolism. In this Perspective paper, we propose that ancestral prokaryotic transport proteins could be responsible for mediating Mg2+ rhythms and posit a feedback model ...
Helen K. Feord, Gerben van Ooijen
wiley +1 more source
Complexity and Philosophy [PDF]
, 2006 The science of complexity is based on a new way of thinking that stands in sharp contrast to the philosophy underlying Newtonian science, which is based on reductionism, determinism, and objective knowledge.
Cilliers, Paul +2 more
core +1 more source