Results 111 to 120 of about 2,646,616 (265)
A Computable Economist’s Perspective on Computational Complexity [PDF]
A computable economist.s view of the world of computational complexity theory is described. This means the model of computation underpinning theories of computational complexity plays a central role.
K. Vela Velupillai
core
Molecular Oncology, EarlyView.Pharmacologic ascorbate (vitamin C) increases ROS, disrupts cellular metabolism, and induces DNA damage in CRPC cells. These effects sensitize tumors to PARP inhibition, producing synergistic growth suppression with olaparib in vitro and significantly delayed tumor progression in vivo. Pyruvate rescue confirms ROS‐dependent activity.
Nicolas Gordon +13 more
wiley +1 more source
Three-Layered Psychological Analysis of an Epidemic: Impact and Legacy of Covid-19
International Journal of Psychoanalysis and Education, 2020 The global emergency caused by the spread of virus known as “Covid-19” caught many people by surprise, revealing the precariousness not only of health, but also of many other areas of our life, such as relationships, the economy, politics or the ...
Francesca Granier +3 more
doaj
Use of complexity theory in health and social care: a scoping review protocol. [PDF]
BMJ Open, 2021 Carroll A, Stokes D, Darley A.
europepmc +1 more source
LDAcoop: Integrating non‐linear population dynamics into the analysis of clonogenic growth in vitro
Molecular Oncology, EarlyView.Limiting dilution assays (LDAs) quantify clonogenic growth by seeding serial dilutions of cells and scoring wells for colony formation. The fraction of negative wells is plotted against cells seeded and analyzed using the non‐linear modeling of LDAcoop.
Nikko Brix +13 more
wiley +1 more source
Implementing technological intelligence systems from the viewpoint of complexity theory
Ingeniería e Investigación, 2008 Technology currently plays a very important role in organisations’ development and competitiveness, thus requiring suitable handling. Technology management has been strengthened by integrating new systematically-applied concepts, such as technological ...
María Elena García Vergara +2 more
doaj
Applying Complexity Theory to a Hospital Complex Patient Care Program. [PDF]
Int J Integr Care, 2021 Borghmans F, Fernandes V, Newnham H.
europepmc +1 more source
Molecular Oncology, EarlyView.We show that the majority of the 18 analyzed recurrent cancer‐associated ERBB4 mutations are transforming. The most potent mutations are activating, co‐operate with other ERBB receptors, and are sensitive to pan‐ERBB inhibitors. Activating ERBB4 mutations also promote therapy resistance in EGFR‐mutant lung cancer.
Veera K. Ojala +15 more
wiley +1 more source
Quantitative Complexity Theory Used in the Prediction of Head-Up Tilt Testing Outcome. [PDF]
Cardiol Res Pract, 2021 Krzesiński P +3 more
europepmc +1 more source
Peroxidasin enables melanoma immune escape by inhibiting natural killer cell cytotoxicity
Molecular Oncology, EarlyView.Peroxidasin (PXDN) is secreted by melanoma cells and binds the NK cell receptor NKG2D, thereby suppressing NK cell activation and cytotoxicity. PXDN depletion restores NKG2D signaling and enables effective NK cell–mediated melanoma killing. These findings identify PXDN as a previously unrecognized immune evasion factor and a potential target to improve
Hsu‐Min Sung +17 more
wiley +1 more source