Results 51 to 60 of about 945,932 (306)

Exploring the dynamics of compliance with community penalties [PDF]

open access: yes, 2008
In this paper, we examine how compliance with community penalties has been theorized hitherto and seek to develop a new dynamic model of compliance with community penalties. This new model is developed by exploring some of the interfaces between existing
Ayres, Ian   +39 more
core   +1 more source

Colorectal cancer‐derived FGF19 is a metabolically active serum biomarker that exerts enteroendocrine effects on mouse liver

open access: yesMolecular Oncology, EarlyView.
Meta‐transcriptome analysis identified FGF19 as a peptide enteroendocrine hormone associated with colorectal cancer prognosis. In vivo xenograft models showed release of FGF19 into the blood at levels that correlated with tumor volumes. Tumoral‐FGF19 altered murine liver metabolism through FGFR4, thereby reducing bile acid synthesis and increasing ...
Jordan M. Beardsley   +5 more
wiley   +1 more source

Ipteks Pengelolaan Risiko Kepatuhan pada PT. Bank Sulutgo [PDF]

open access: yes, 2018
In running a business, the company cannot be separated from the risks that can threaten the company. Risks that arise require attention and improvement so that a business can survive and compete in the business world.
Rawis, G. G. (Gracela)   +1 more
core  

Repeat prescribing of medications: a system-centred risk management model for primary care organisations [PDF]

open access: yes, 2017
Rationale, aims and objectives: Reducing preventable harm from repeat medication prescriptions is a patient safety priority worldwide. In the United Kingdom, repeat prescriptions items issued has doubled in the last 20 years from 5.8 to 13.3 items ...
Bartlett, Stephen   +5 more
core   +1 more source

Incentives and Culture in Risk Compliance

open access: yesSSRN Electronic Journal, 2017
In the finance industry, risk compliance has become an important issue after numerous policy violations resulting in significant costs for financial institutions and society as a whole. Little evidence currently exists on the drivers of non-compliant behavior.
Elizabeth Sheedy   +2 more
openaire   +1 more source

Genetic attenuation of ALDH1A1 increases metastatic potential and aggressiveness in colorectal cancer

open access: yesMolecular Oncology, EarlyView.
Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova   +25 more
wiley   +1 more source

Plan Now for Managing Electronic Data and Avoid Tomorrow’s Legal Risks [PDF]

open access: yes, 2007
[Excerpt] In a world where the use of electronic data is rapidly increasing, companies must find ways to manage data now so that they effectively control compliance risks. The proliferation of electronic data is both astonishing and overwhelming.
Jackson, Cynthia
core   +1 more source

AI management an exploratory survey of the influence of GDPR and FAT principles [PDF]

open access: yes, 2020
As organisations increasingly adopt AI technologies, a number of ethical issues arise. Much research focuses on algorithmic bias, but there are other important concerns arising from the new uses of data and the introduction of technologies which may ...
Addis, MC, Kutar, MS
core   +1 more source

Engineered extracellular vesicles enriched with the miR‐214/199a cluster enhance the efficacy of chemotherapy in ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang   +12 more
wiley   +1 more source

The Evolution of International Environmental Law [PDF]

open access: yes, 2011
In the last forty years, international environmental law has evolved rapidly, as environmental risks have become more apparent and their assessment and management more complex.
Brown Weiss, Edith
core   +1 more source

Home - About - Disclaimer - Privacy