Genetic and epigenetic changes in host ABCB1 influences malaria susceptibility to Plasmodium falciparum. [PDF]
Multiple mechanisms such as genetic and epigenetic variations within a key gene may play a role in malarial susceptibility and response to anti-malarial drugs in the population.
Himanshu Gupta +8 more
doaj +1 more source
Drug resistance mediating Plasmodium falciparum polymorphisms and clinical presentations of parasitaemic children in Uganda. [PDF]
BackgroundPlasmodium falciparum genetic polymorphisms that mediate altered drug sensitivity may impact upon virulence. In a cross-sectional study, Ugandan children with infections mutant at pfcrt K76T, pfmdr1 N86Y, or pfmdr1 D1246Y had about one-fourth ...
Arinaitwe, Emmanuel +8 more
core +1 more source
Background: Malaria remains a major health hazard in the modern world, particularly in developing countries. In Plasmodium falciparum malaria, there is a direct correlation between asexual erythrocytic stage parasite density and disease severity ...
Praveen Mangal +5 more
doaj +1 more source
Falciparum malaria-induced acute pancreatitis
Falciparum malaria is one of the most common causes of acute febrile illness in India and frequently presents as severe malaria also known as complicated malaria or cerebral malaria with associated multiple organ failure.
Shankar Roy +4 more
doaj +1 more source
Anti-inflammatory cytokines predominate in acute human Plasmodium knowlesi infections. [PDF]
Plasmodium knowlesi has entered the human population of Southeast Asia. Naturally acquired knowlesi malaria is newly described with relatively little available data, including data on the host response to infection.
Janet Cox-Singh +5 more
doaj +1 more source
Myocarditis associated with malarial fever: An unusual presentation
Malaria is endemic in India and complicated malaria is usually caused by Plasmodium (P) falciparum, but Plasmodium vivax can also cause life-threatening conditions in some cases.
Anoop Kumar +5 more
doaj +1 more source
Throat and rectal swabs may have an important role in MRSA screening of critically ill patients.
OBJECTIVE: Methicillin-resistant Staphylococcus aureus (MRSA) is a major problem in intensive care units (ICU). International guidelines recommend screening patients for MRSA on admission, although consensus on sites required for optimum detection has ...
Batra, Rahul +3 more
core +1 more source
Suspected Artesunate Resistant Malaria in South India
We report four cases of complicated malaria in Andhra Pradesh-Orissa border between July 2016 and December 2016, with apparent treatment failure with artemisinin drugs, and all showing parasitological clearance after quinine and adjuvant clindamycin ...
Shalini Akunuri +3 more
doaj +1 more source
Adherence to a Six-Dose Regimen of Artemether-Lumefantrine for Treatment of Uncomplicated Plasmodium Falciparum Malaria in Uganda. [PDF]
Measuring baseline levels of adherence and identifying risk factors for non-adherence are important steps before the introduction of new antimalarials. In Mbarara in southwestern Uganda, we assessed adherence to artemether-lumefantrine (Coartem) in its ...
Bajunirwe, F +9 more
core +2 more sources
The influence of late-stage pupal irradiation and increased irradiated:un-irradiated male ratio on mating competitiveness of the malaria mosquito Anopheles arabiensis Patton [PDF]
Competitiveness of released males in genetic control programmes is of critical importance. In this paper, we explored two scenarios to compensate for the loss of mating competitiveness after pupal stage irradiation in males of the malaria mosquito ...
Helinski, M., Knols, B.G.J.
core +2 more sources

