Results 121 to 130 of about 2,006,814 (315)
IEEE Access, 2018 Component-based software (CBS) development is an attractive proposition to globally distributed software development organizations because of its potential to integrate reusable components in new products.
Muhammad Jalal Khan, Sajjad Mahmood
doaj +1 more source
Diversity and complexity in neural organoids
FEBS Letters, EarlyView.Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley +1 more source
Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation
FEBS Letters, EarlyView.Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz +11 more
wiley +1 more source
Java Applications Development Based on Component and Metacomponent Approach
Journal of Information and Organizational Sciences, 2008 Component based modeling offers new and improved approach to design, construction, implementation and evolution of software applications development. This kind of software applications development is usually represented by appropriate component model ...
Danijel Radošević +2 more
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A holistic semantic based approach to component specification and retrieval [PDF]
Component-Based Development (CBD) has been broadly used in software development as it enhances the productivity and reduces the costs and risks involved in systems development. It has become a well-understood and widely used technology for developing not
Li, Chengpu
core
The ubiquitin ligase RNF115 is required for the clearance of damaged lysosomes
FEBS Letters, EarlyView.Upon lysosomal rupture, an E3 ubiquitin ligase RNF115 translocates from the cytosol to the damaged lysosomal membrane. Moreover, RNF115 depletion impairs the clearance of damaged lysosomes, identifying it as a key regulator of lysosomal quality control.
Sae Nakanaga +3 more
wiley +1 more source
FEBS Letters, EarlyView.Plasma membranes contain dynamic nanoscale domains that organize lipids and receptors. Because viruses operate at similar scales, this architecture shapes early infection steps, including attachment, receptor engagement, and entry. Using influenza A virus and HIV‐1 as examples, we highlight how receptor nanoclusters, multivalent glycan interactions ...
Jan Schlegel, Christian Sieben
wiley +1 more source
Evolution management of extra-functional properties in component-based embedded systems
, 2011 As software complexity increases in embedded systems domain, component-based development becomes increasingly attractive. A main challenge in this approach is however to analyze the system's extra-functional properties (such as timing properties, or ...
Ciccozzi, Federico, +7 more
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FEBS Letters, EarlyView.Embryo‐like structures (stembryos) are an innovative tool, but they are hindered by experimental variability and limited developmental potential. DNA methylation is crucial for mammalian development, but its status in stembryo models is poorly characterized.
Sara Canil +4 more
wiley +1 more source
Formal Definition of Collaborative Spaces
Acta Universitaria, 2012 Collaborative spaces are widely used for diverse organizations and purposes. Despite the fact that technological solutions exist there is a lack of methodological support to develop such environments.
Claudia Zepeda-Cortés +2 more
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