Results 101 to 110 of about 2,006,814 (315)
Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?
FEBS Letters, EarlyView.This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes +3 more
wiley +1 more source
The Unified Process for Component-Based Development [PDF]
, 1999 A better development process-in fact, a process unifying the best practices now available-is the key to the software future. The proven Unified Process originally developed by Ivar Jacobson, now incorporating the work of Grady Booch, Jim Rumbaugh, Philippe Kruchten, Walker Royce, and other people inside Rational, answers this long-felt need.
openaire +1 more source
Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation
FEBS Letters, EarlyView.Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe +3 more
wiley +1 more source
Optimization of Component Connections for an Embedded Component System [PDF]
, 2009 Software component techniques are widely used to enhance productivity and reduce the cost of software systems development. This paper proposes optimization of component connections for a component system that is suitable for embedded systems.
Oyama, Hiroshi +5 more
core +1 more source
FEBS Letters, EarlyView.We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee +3 more
wiley +1 more source
Towards mode switch handling in component-based multi-mode systems
, 2012 Component-based software engineering (CBSE) is becoming a prominent solution to the development of complex embedded systems. Meanwhile, partitioning system behavior into different modes is an effective approach to reduce system complexity.
Hang Yin +5 more
core +1 more source
FEBS Letters, EarlyView.We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley +1 more source
A Component-based Software Development and Execution Framework for CAx Applications
Acta Polytechnica, 2004 Digitalization of the manufacturing process and technologies is regarded as the key to increased competitive ability. The MZ-Platform infrastructure is a component-based software development framework, designed for supporting enterprises to enhance ...
N. Matsuki, H. Tokunaga, H. Sawada
doaj
A New Paradigm for Component-based Development
Journal of Software, 2012 Hancock and Setzer describe how Haskell’s monolithic IO monad can be decomposed into worlds when working in a dependently typed language, like Martin-Lof’s type theory. This paper introduces the notion of world map and shows that worlds and world maps form a category with arbitrary products.
openaire +1 more source
Proposing a secure component-based-application logic and system’s integration testing approach [PDF]
, 2019 Software engineering moved from traditional methods of software enterprise applications to com-ponent based development for distributed system’s applications. This new era has grown up forlast few years, with component-based methods, for design and rapid
Nabi, Faisal +2 more
core +1 more source