Results 81 to 90 of about 105,174 (312)
Molecular Oncology, EarlyView.Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau +36 more
wiley +1 more source
Molecular Oncology, EarlyView.Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch +13 more
wiley +1 more source
The influence of semi-rigid connections on the performance of steel framed structures in fire. [PDF]
, 1997 Observation of fire damaged structures and recent fire tests at the Cardington LBTF have suggested that even nominally `simple' connections are capable of providing significant restraint at elevated-temperatures. As most frames
Leston-Jones, L.C. +1 more
core
Characterisation of beam-to-column composite joints beyond current Eurocode provisions
, 2018 [EN] In EN 1994-1, design rules are given for the evaluation of the mechanical properties of structural steel-concrete composite joints (rotational stiffness, resistance and ductility) based on the component method offered in EN 1993-1-8 and adding ...
Ciutina, A., Demonceau, Jean-François
core +1 more source
Axial Compression Behaviours of Pultruded GFRP–Wood Composite Columns
Sensors, 2019 An innovative pultruded fiber reinforced polymer (FRP)⁻wood composite (PFWC) column with a lightweight southern pine wood core confined by outer FRP sheets was manufactured using an improved pultrusion process.
Yujun Qi +4 more
doaj +1 more source
Molecular Oncology, EarlyView.We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric +10 more
wiley +1 more source
Simulation model for ultra-high strength concrete filled composite column under static loads
, 2012 Previous experimental research at National University of Singapore on ultra-high strength concrete (UHSC) filled composite columns exhibits that the brittleness of UHSC of compressive strength up to 200MPa can be overcome due to the passively confinement
Liew, J. Y. Richard +1 more
core
SNAP-TITE Composite Column Reinforcement
, 2007 Recent earthquakes throughout the world have demonstrated the vulnerabilities of older reinforced concrete columns to seismic deformation demands. The Snap Tite Composite Column Reinforcement strengthens a concrete column by confining it in an external ...
ECT Team, Purdue
core +2 more sources
Molecular Oncology, EarlyView.Pancreatic sensory neurons innervating healthy and PDAC tissue were retrogradely labeled and profiled by single‐cell RNA sequencing. Tumor‐associated innervation showed a dominant neurofilament‐positive subtype, altered mitochondrial gene signatures, and reduced non‐peptidergic neurons.
Elena Genova +14 more
wiley +1 more source
Sensors, 2018 Fibre-reinforced polymer (FRP) is used widely in concrete structures owing to its noncorrosive, light-weight, nonmagnetic, and high tensile-strength properties.
Fang Yuan +3 more
doaj +1 more source