Results 71 to 80 of about 50,371 (314)
FEBS Letters, EarlyView.Protein aggregates threaten proteostasis and cell health. In human cells, Hsp70–J‐domain protein‐based disaggregases remove aggregates, but how they assemble remains unclear. Our biochemical findings show that DNAJA2‐ and DNAJB1‐containing disaggregase scaffolds enhance luciferase aggregate targeting, and that Hsp70 recruitment by both J‐domain ...
Anna Szlachcic, Nadinath B. Nillegoda
wiley +1 more source
FEBS Letters, EarlyView.The process of internalization of the Shiga toxin A subunit via formation of a complex with the Shiga toxin B subunit, which specifically binds to the Gb3 receptor. The peptide is designed to act as a carrier of drugs into cancer cells. Here, we explored the potential of peptides derived from the catalytic A subunit of Shiga toxin (STxA) to be drug ...
Giulia Opassi +6 more
wiley +1 more source
Collapse behaviour of steel columns in fire. [PDF]
, 1988 The three years' work undertaken in this project is a purely numerical analysis of the inelastic behaviour of steel columns in fire. This is made up of three main parts, each devoted to the development and use of a numerical technique to study the ...
Olawale, Aderemi Olayiwola, Olawale, A.O
core
Experimental tests on biaxially loaded concrete-encased composite columns
, 2008 This paper reports an experimental investigation of the behaviour of concrete-encased composite columns subjected to short-term axial load and biaxial bending.
Tokgoz S., Dundar C.
core +1 more source
Conserved binding mode but diverse interfaces of MreC‐PBP2 interactions
FEBS Letters, EarlyView.The crystal structure of abMreC reveals a conserved two β‐barrel architecture and provides structural insights into its role within the bacterial elongasome. The abMreC–abPBP2 complex model identifies the molecular basis of MreC‐mediated PBP2 recognition, contributing to the regulation of peptidoglycan synthesis.
Hyunseok Jang +4 more
wiley +1 more source
Research in composite concrete filled columns
, 2011 NoComposite concrete filled steel tube columns are increasingly used for high-rise building structures, owing to their excellent structural performance such as superior load-bearing capacity, high ductility, good energy dissipation and fire behaviour ...
Lam, Dennis
core
Shear Transfer in Heavy Steel-Concrete Composite Columns with Multiple Encased Steel Profiles [PDF]
, 2019 The PhD Thesis is dealing with the shear transfer in heavy steel-concrete composite columns with multiple encased steel profiles. In the conducted research, a focus was placed on two aspects of shear transfer: (1) local shear transfer at the steel ...
CHRZANOWSKI, Maciej
core
BuildingsAs a key load-bearing component in building structures, the effective strengthening of reinforced concrete (RC) columns is critical to enhancing their structural reliability and service life.
Jing Zhu +4 more
doaj +1 more source
Mechanical Analysis of Hpfrcc Precasted Composite Column
MaterialsIn order to improve the physical and mechanical properties and the ability to perform in practical applications of prefabricated monolithic composite columns, high-performance fiber-reinforced cementitious composites (HPFRCC) material was prefabricated into mold shells to form HPFRCC precast monolithic composite columns.
Tingting Lu +3 more
openaire +2 more sources
Molecular Oncology, EarlyView.Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat +8 more
wiley +1 more source