Results 81 to 90 of about 50,371 (314)
Molecular Oncology, EarlyView.Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau +36 more
wiley +1 more source
Three-dimensional analysis of steel frames and subframes in fire. [PDF]
, 1994 The aim of the present work is to develop a sophisticated analytical model for columns within three-dimensional assemblies in fire conditions. A preliminary investigation into this problem resulted in the development of a simplified approach for the ...
Najjar, S.R., Najjar, Samer Rida
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Molecular Oncology, EarlyView.Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch +13 more
wiley +1 more source
Instability of composite beams in hogging bending [PDF]
This work is concerned with local buckling and lateral distortional buckling, two aspects of instability that govern the design of composite beams in hogging regions.
Chen, Shiming
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Structural response of concrete-filled elliptical steel hollow sections under eccentric compression [PDF]
, 2012 The purpose of this research is to examine the behaviour of elliptical concrete-filled steel tubular stub columns under a combination of axial force and bending moment. Most of the research carried out to date involving concrete-filled steel sections has
Sheehan, Therese +9 more
core +1 more source
Slenderness effect on the behavior of composite RC columns under eccentric loads [PDF]
Engineering and Technology JournalThe structural performance of reinforced concrete (RC) columns plays a pivotal role in ensuring the safety and stability of buildings and infrastructure. In structural engineering, the quest for optimizing the design and behavior of RC columns has been a
Zaynab Mohammed +2 more
doaj +1 more source
Molecular Oncology, EarlyView.We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric +10 more
wiley +1 more source
Molecular Oncology, EarlyView.Pancreatic sensory neurons innervating healthy and PDAC tissue were retrogradely labeled and profiled by single‐cell RNA sequencing. Tumor‐associated innervation showed a dominant neurofilament‐positive subtype, altered mitochondrial gene signatures, and reduced non‐peptidergic neurons.
Elena Genova +14 more
wiley +1 more source
Behaviour of concrete-filled steel tubular stub columns with different aggregates
, 2015 A series of tests on concrete-filled steel tubular (CFST) stub columns under axial compression was presented in this paper. Five different concrete mixes with the same cement content and water/cement ratio were designed using normal limestone aggregate ...
Tao, Zhong (R12091) +2 more
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, 2010 Interaction curves for vibration and buckling of thin-walled composite box beams with arbitrary lay-ups under constant axial loads and equal end moments are presented.
Lee, Jaehong, Vo, Thuc
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