Results 161 to 170 of about 10,977,169 (397)

Bio-composite material

open access: yes, 2014
The European Project Semester (EPS) is a programme offered by 13 European universities in 11 countries throughout Europe to students who have completed at least two years of study. It is a four-month program and it is a mixture of “Project Related Courses” and project organized/problem based learning.
Closa Pasquina, Raquel   +4 more
openaire   +1 more source

Targeting the MDM2‐MDM4 interaction interface reveals an otherwise therapeutically active wild‐type p53 in colorectal cancer

open access: yesMolecular Oncology, EarlyView.
This study investigates an alternative approach to reactivating the oncosuppressor p53 in cancer. A short peptide targeting the association of the two p53 inhibitors, MDM2 and MDM4, induces an otherwise therapeutically active p53 with unique features that promote cell death and potentially reduce toxicity towards proliferating nontumor cells.
Sonia Valentini   +10 more
wiley   +1 more source

Thermal proteome profiling and proteome analysis using high‐definition mass spectrometry demonstrate modulation of cholesterol biosynthesis by next‐generation galeterone analog VNPP433‐3β in castration‐resistant prostate cancer

open access: yesMolecular Oncology, EarlyView.
Elevated level of cholesterol is positively correlated to prostate cancer development and disease severity. Cholesterol‐lowering drugs, such as statins, are demonstrated to inhibit prostate cancer. VNPP433‐3β interrupts multiple signaling and metabolic pathways, including cholesterol biosynthesis, AR‐mediated transcription of several oncogenes, mRNA 5′
Retheesh S. Thankan   +10 more
wiley   +1 more source

Thermophysical properties of aluminum-base composite materials [PDF]

open access: bronze, 1979
D. M. Karpinos   +3 more
openalex   +1 more source

Effect on microstructure and mechanical properties of friction stir welded 5A06 aluminum alloy joints by deep cryogenic treatment

open access: yesMaterials Research Express
In order to improve the comprehensive mechanical properties of the welded joints of the 5A06 aluminum alloy, friction stir welded (FSW) joints were subjected to deep cryogenic treatment (DCT).
Jingjing Du   +8 more
doaj   +1 more source

Elucidating prognostic significance of purine metabolism in colorectal cancer through integrating data from transcriptomic, immunohistochemical, and single‐cell RNA sequencing analysis

open access: yesMolecular Oncology, EarlyView.
Low expression of five purine metabolism‐related genes (ADSL, APRT, ADCY3, NME3, NME6) was correlated with poor survival in colorectal cancer. Immunohistochemistry analysis showed that low NME3 (early stage) and low ADSL/NME6 (late stage) levels were associated with high risk.
Sungyeon Kim   +8 more
wiley   +1 more source

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