Results 131 to 140 of about 18,459,682 (262)

Transcripts enriched in codons that trigger P‐site tRNA‐mediated mRNA decay possess stable mRNA

open access: yesFEBS Open Bio, EarlyView.
PTMD codons were first described by Mendel et al. as mediators of an mRNA decay pathway dependent on the human protein CNOT3, homologous to yeast Not5. Our findings confirm that PTMD codons destabilize transcripts; however, unlike in yeast, the human pathway specifically targets and slightly destabilizes primarily stable mRNAs.
Rodolfo Lopes Carneiro   +1 more
wiley   +1 more source

Composite Materials Engineering Graduating Class Photograph: 2001

open access: yes, 2001
This is a class photograph of the Composite Materials Engineering Graduating Class of 2001 at Winona State University. The students in the photograph are: Nathan Bergler, Michael Boraas, Curtis Cichanowski, Michael Cisewski, Bryan Clark, Joseph Dietsch ...
Composite Materials Engineering Department-Winona State University
core  

Hyperosmotic stress‐induced redistribution of pre‐mRNA cleavage factor I subunits is associated with shifts in alternative polyadenylation

open access: yesFEBS Open Bio, EarlyView.
Hyperosmotic stress triggers the relocation of the CFIm complex from the nucleus to the cytoplasm. This shift creates a nuclear ‘stoichiometric bottleneck’, limiting CFIm availability for mRNA processing. Consequently, specific mRNAs like NUDT21 and DICER1 undergo targeted 3′UTR shortening, demonstrating how spatial protein dynamics drive rapid ...
Hitomi Soumiya   +2 more
wiley   +1 more source

Composite Materials Engineering Graduating Class Photograph: 2006

open access: yes, 2006
This is a class photograph of the Composite Materials Engineering Graduating Class of 2006 at Winona State University. The students in the photograph are: Jarald Chao, Matthew DeCann, Douglas Drazkowski, Katrina Gass-Callahan, Nicholas Jennings, Paul ...
Composite Materials Engineering Department-Winona State University
core  

Treatment with KCL‐286, a first‐in‐class retinoic acid receptor‐β (RARβ) agonist, ameliorates neuronal DNA damage and inflammation in a mouse model of Alzheimer's disease

open access: yesFEBS Open Bio, EarlyView.
Repair of neuronal DNA damage in Alzheimer's disease by KCL‐286. (A) Amyloid‐β oligomers and plaques impair neuronal DNA repair pathways, leading to DNA double‐strand breaks and glial activation. (B) KCL‐286 activates RARβ/RXR signalling via retinoic acid response elements (RAREs), associated with increased BRCA1 expression, enhanced DNA repair and ...
Natasha Hill   +6 more
wiley   +1 more source

Pathways and pitfalls: a qualitative study of student experiences in biomedical science education

open access: yesFEBS Open Bio, EarlyView.
Biomedical science students from underrepresented backgrounds face barriers including financial strain, disrupted laboratory access and cultural exclusion. Peer networks provide vital support when institutional systems are difficult to navigate. To create inclusive learning environments and achieve academic success, educators should blend active, hands‐
Olivia J. Russell   +8 more
wiley   +1 more source

Puncturing strategies for incremental redundancy schemes using rate compatible systematic serially concatenated codes

open access: yes, 2006
A rate compatible puncturing strategy intended for incremental redundancy retransmission schemes is derived. In particular, systematic serially concatenated codes with two or more component codes are considered, although the method is applicable to any ...
Uhlemann, Elisabeth   +6 more
core  

MagmaFlow: A desktop platform for artificial intelligence‐driven expression analysis

open access: yesFEBS Open Bio, EarlyView.
MagmaFlow is a free, no‐code platform for gene expression analysis. It generates interactive volcano plots, links genes to literature, pathways, and diseases, prioritizes candidates using millions of publications, identifies affected biological processes, builds network diagrams, and exports publication‐ready figures and reports for macOS and Windows ...
Carlos E. Buss   +7 more
wiley   +1 more source

Composite Materials Engineering Graduating Class Photograph: 2013

open access: yes, 2013
This is a class photograph of the Composite Materials Engineering Graduating Class of 2013 at Winona State University. The students in the photograph are: Brennan Ashton, Calvin Derleth, S.
Composite Materials Engineering Department-Winona State University
core  

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