Results 101 to 110 of about 664,097 (240)

Damage Tolerance Of Basalt Fiber Reinforced Multiscale Composites: Effect Of Nanoparticle Morphology And Hygrothermal Aging [PDF]

open access: yes
COMPOSITES PART B-ENGINEERINGBarely visible impact damages of fiber-reinforced polymers (FRPs) have been the subject of much systematic investigation, specifically with the combination of the service conditions. Introducing nanoparticles into the polymer
Avcı, Ahmet   +4 more
core   +1 more source

Investigating transcription factor dynamics in health and disease using FRAP

open access: yesFEBS Letters, EarlyView.
FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj   +3 more
wiley   +1 more source

Confining iodide migration with quantified barrier for durable perovskite solar cells

open access: yesNature Communications
The migration of iodide ions out of the perovskite film degrades charge transport and electrode layers, reducing the long-term stability of perovskite solar cells.
Hongcai Tang   +4 more
doaj   +1 more source

Conserved binding mode but diverse interfaces of MreC‐PBP2 interactions

open access: yesFEBS Letters, EarlyView.
The crystal structure of abMreC reveals a conserved two β‐barrel architecture and provides structural insights into its role within the bacterial elongasome. The abMreC–abPBP2 complex model identifies the molecular basis of MreC‐mediated PBP2 recognition, contributing to the regulation of peptidoglycan synthesis.
Hyunseok Jang   +4 more
wiley   +1 more source

Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential

open access: yesFEBS Letters, EarlyView.
Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta   +3 more
wiley   +1 more source

Structure‐forward targeting of claudins with synthetic binders

open access: yesFEBS Letters, EarlyView.
Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley   +1 more source

Synchronized crystallization in tin-lead perovskite solar cells

open access: yesNature Communications
Tin-lead halide perovskites with a bandgap near 1.2 electron-volt hold great promise for thin-film photovoltaics. However, the film quality of solution-processed Sn-Pb perovskites is compromised by the asynchronous crystallization behavior between Sn and
Yao Zhang   +10 more
doaj   +1 more source

Addressing data scarcity in deep learning: Leveraging real and artificial datasets to predict compaction of composites

open access: yesMaterials & Design
This study focuses on predicting the compaction behaviour of composite materials under processing conditions using Long Short-Term Memory (LSTM) neural networks.
Anatoly Koptelov   +4 more
doaj   +1 more source

Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation

open access: yesFEBS Letters, EarlyView.
Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang   +2 more
wiley   +1 more source

Comparison of vacuum assisted resin infusion and resin transfer moulding on thickness uniformity, surface quality and mechanical properties of flax fibre bio-epoxy composites

open access: yesDiscover Materials
Composites composed of plant fibres and bio-based resin systems expand the range of sustainable materials for lightweight applications. However, natural fibres require special handling during manufacturing due to their high hydrophilic nature in order to
Lorenz Walter   +2 more
doaj   +1 more source

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