Results 81 to 90 of about 36,842 (283)
Actions and Events in Concurrent Systems Design
, 2014 In this work, having in mind the construction of concurrent systems from components, we discuss the difference between actions and events. For this discussion, we propose an(other) architecture description language in which actions and events are made ...
Cassano, Valentin, Maibaum, Thomas S. E.
core +2 more sources
FEBS Letters, EarlyView.Structural and biochemical characterisations show that the planar cell polarity (PCP) protein Inturned harbours a unique PDZ‐like domain that does not bind canonical PDZ‐binding motifs (PBMs) like that of another PCP protein Vangl2. In contrast, the apical‐basal polarity protein Scribble contains four PDZ domains that bind Vangl2, but one PDZ domain ...
Stephan Wilmes +4 more
wiley +1 more source
Singular and Plural Functions for Functional Logic Programming
, 2012 Functional logic programming (FLP) languages use non-terminating and non-confluent constructor systems (CS's) as programs in order to define non-strict non-determi-nistic functions.
ADRIÁN RIESCO +35 more
core +1 more source
Tau acetylation at K331 has limited impact on tau pathology in vivo
FEBS Letters, EarlyView.We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto +3 more
wiley +1 more source
Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
FEBS Letters, EarlyView.Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley +1 more source
Musical Thought And Compositionality [PDF]
, 2006 Many philosophers and music theorists have claimed that music is a language, though whether this is meant metaphorically or literally is often unclear.
Bartel, Christopher
core
MORSE: Semantic-ally Drive-n MORpheme SEgment-er
, 2017 We present in this paper a novel framework for morpheme segmentation which uses the morpho-syntactic regularities preserved by word representations, in addition to orthographic features, to segment words into morphemes.
Bhat, Suma +2 more
core +1 more source
Molecular Oncology, EarlyView.Detection of extrachromosomal circular DNA (eccDNA) in plasma samples from EGFR‐mutated non‐small cell lung cancer patients. Plasma was collected before and during treatment with the EGFR‐tyrosine kinase inhibitor osimertinib. Plasma eccDNA was detected in all cancer samples, and the presence of the EGFR gene on eccDNA serves as a potential biomarker ...
Simone Stensgaard +5 more
wiley +1 more source
Molecular Oncology, EarlyView.Development of therapies targeting cancer‐associated fibroblasts (CAFs) necessitates preclinical model systems that faithfully represent CAF–tumor biology. We established an in vitro coculture system of patient‐derived pancreatic CAFs and tumor cell lines and demonstrated its recapitulation of primary CAF–tumor biology with single‐cell transcriptomics ...
Elysia Saputra +10 more
wiley +1 more source
Studies in Logic, Grammar and Rhetoric, 2015 The paper concentrates on the problem of adequate reflection of fragments of reality via expressions of language and inter-subjective knowledge about these fragments, called here, in brief, language adequacy. This problem is formulated in several aspects,
Wybraniec-Skardowska Urszula
doaj +1 more source