Results 11 to 20 of about 939,531 (119)

Angiotensin II type 2 receptor agonist Compound 21 attenuates pulmonary inflammation in a model of acute lung injury. [PDF]

J Inflamm Res, 2018
Menk M, Graw JA, von Haefen C, Steinkraus H, Lachmann B, Spies CD, Schwaiberger D.   +6 more
europepmc   +1 more source

Phosphorus-Nitrogen Compounds. 21. Syntheses, Structural Investigations,

, 2010
The reactions of hexachlorocyclotriphosphazatriene, N3P3Cl6, with N/O-donor-type N-alkyl (or aryl)-o-hydroxybenzylamines (la-le) produce mono- (2a-2e), di- (3a-3d), and tri- (4a and 4b) spirocyclic phosphazenes. The tetrapyrrolidino monospirocyclic phosphazenes (2f-2i) are prepared from the reactions of partly substituted compounds (2a-2d) with excess ...
Isiklan, M, Asmafiliz, N, Ozalp, EE, Ilter, EE, Kilic, Z, Cosut, B, Yesilot, S, Kilic, A, Ozturk, A, Hokelek, T, Bilir, LYK, Acik, L, Akyuz, E   +12 more
openaire   +2 more sources

DREADD agonist compound 21 causes acute diuresis in wild-type mice. [PDF]

Front Pharmacol
MacIver B, Wu A, Hill WG, Yu W.
europepmc   +1 more source

Dose-response, therapeutic time-window and tPA-combinatorial efficacy of compound 21: A randomized, blinded preclinical trial in a rat model of thromboembolic stroke. [PDF]

J Cereb Blood Flow Metab, 2019
Ishrat T, Fouda AY, Pillai B, Eldahshan W, Ahmed H, Waller JL, Ergul A, Fagan SC.   +7 more
europepmc   +1 more source

Compound 21 Attenuates Isoflurane-Induced Injury in Neonatal Rat Hippocampal Neurons and Primary Rat Neuronal Cells by Upregulating METTL3. [PDF]

J Inflamm Res
Shen Y, Wu Y, Zhuang H, Chen Z, Zhang Q, Li P, Wang J, Huang Z, Zeng Q.   +8 more
europepmc   +1 more source

The Effect of a Nonpeptide Angiotensin II Type 2 Receptor Agonist, Compound 21, on Aortic Aneurysm Growth in a Mouse Model of Marfan Syndrome. [PDF]

J Cardiovasc Pharmacol, 2018
Verbrugghe P, Verhoeven J, Clijsters M, Vervoort D, Schepens J, Meuris B, Herijgers P.   +6 more
europepmc   +1 more source

The novel AT2 receptor ligand, β-Pro7 Ang III, induces equivalent anti-fibrotic effects to Compound 21 but broader anti-fibrotic effects than pirfenidone in mice with bleomycin-induced pulmonary fibrosis. [PDF]

Clin Sci (Lond)
Royce SG, Erdem C, Mao W, Wang Y, Del Borgo MP, Widdop RE, Samuel CS.   +6 more
europepmc   +1 more source

Role of interleukin-10 in the neuroprotective effect of the Angiotensin Type 2 Receptor agonist, compound 21, after ischemia/reperfusion injury. [PDF]

Eur J Pharmacol, 2017
Fouda AY, Pillai B, Dhandapani KM, Ergul A, Fagan SC.   +4 more
europepmc   +1 more source

The Selective Angiotensin II Type 2 Receptor Agonist, Compound 21, Attenuates the Progression of Lung Fibrosis and Pulmonary Hypertension in an Experimental Model of Bleomycin-Induced Lung Injury. [PDF]

Front Physiol, 2018
Rathinasabapathy A, Horowitz A, Horton K, Kumar A, Gladson S, Unger T, Martinez D, Bedse G, West J, Raizada MK, Steckelings UM, Sumners C, Katovich MJ, Shenoy V.   +13 more
europepmc   +1 more source

Clozapine N-oxide, compound 21, and JHU37160 do not influence effortful reward-seeking behavior in mice. [PDF]

Psychopharmacology (Berl)
Aomine Y, Oyama Y, Sakurai K, Macpherson T, Ozawa T, Hikida T.   +5 more
europepmc   +1 more source