Results 11 to 20 of about 985,715 (260)
Synthesis and Crystal Structure of Dibromido{[(2-Pyridyl) methyl](p-ethylphenyl)amine}Zinc [PDF]
Chemical Review and Letters, 2022 The structure of compound has also been examined crystallographically. It crystallizes in the monoclinic space group P 21/c. The title compound has been synthesized from the reaction of 4-ethyl-N-((pyridin-2-yl) methylene) benzeneamine with ZnBr2 metal ...
Seyed Jalal Hoseyni +2 more
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Frontiers in Neuroscience, 2017 Objectives: Angiotensin II, glutamate and gamma-aminobutyric acid (GABA) interact within the rostral ventrolateral medulla (RVLM) and the paraventricular nucleus (PVN) modulating the central regulation of blood pressure and sympathetic tone.
Laura Légat +9 more
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Anti-fibrotic Potential of AT2 Receptor Agonists
Frontiers in Pharmacology, 2017 There are a number of therapeutic targets to treat organ fibrosis that are under investigation in preclinical models. There is increasing evidence that stimulation of the angiotensin II type 2 receptor (AT2R) is a novel anti-fibrotic strategy and we have
Yan Wang +9 more
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BMC Chemistry, 2022 Introduction Aurora-A kinase is associated with the Aurora kinase family which has been considered a striking anticancer target for the treatment of human cancers.
Meenu Beniwal +3 more
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Crystals, 2012 A facile one-pot synthesis of methyl 5-(4-chlorobenzoyloxy)-1-phenyl-1H-pyrazole-3-carboxylate (4) is described. The title compound was efficiently synthesized by the reaction of phenyl hydrazine, dimethyl acetylenedicarboxylate and 4-chlorobenzoyl ...
Imtiaz Khan, Jonathan M. White
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Life, 2023 Background: Sustained microglial activation contributes to the development of post-stroke cognitive impairment (PSCI). Compound 21 (C21), an angiotensin II type 2 receptor agonist, has shown some neurovascular protection after stroke. This study aimed to
Abdulkarim Alshammari +7 more
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Two New Koumine-Type Indole Alkaloids from Gelsemium elegans Benth.
Molecules, 2013 Two new indole alkaloids, 21-oxokoumine (1) and furanokoumine (2), were isolated from the roots of Gelsemium elegans Benth together with three known compounds.
Huanhuan Gao +4 more
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Novel epigallocatechin-3-gallate (EGCG) derivative as a new therapeutic strategy for reducing neuropathic pain after chronic constriction nerve injury in mice. [PDF]
PLoS ONE, 2015 Neuropathic pain is common in peripheral nerve injury and often fails to respond to ordinary medication. Here, we investigated whether the two novel epigallocatechin-3-gallate (EGCG) polyphenolic derivatives, compound 23 and 30, reduce the neuropathic ...
Xavier Xifró +6 more
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Revista Ingenio, 2016 This document presents the identification of valves and flanged unions of a plant for the processing and transformation of hydrocarbons. The identification was carried out in order to monitor the elements (flanged joints and valves) according to the ...
Edwin Espinel Blanco +2 more
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Design and Synthesis of AMPK Activators and GDF15 Inducers
Molecules, 2023 Targeting growth differentiation factor 15 (GDF15) is a recent strategy for the treatment of obesity and type 2 diabetes mellitus (T2DM). Here, we designed, synthesized, and pharmacologically evaluated in vitro a novel series of AMPK activators to ...
Meijian Zhang +7 more
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