Results 21 to 30 of about 2,189,580 (292)

Stimulation of Angiotensin II Type 2 Receptor Modulates Pro-Inflammatory Response in Microglia and Macrophages: Therapeutic Implications for the Treatment of Stroke

Life, 2023
Background: Sustained microglial activation contributes to the development of post-stroke cognitive impairment (PSCI). Compound 21 (C21), an angiotensin II type 2 receptor agonist, has shown some neurovascular protection after stroke. This study aimed to
Abdulkarim Alshammari, Yohan Han, Timothy W. Jones, Bindu Pillai, Duo Zhang, Adviye Ergul, Payaningal R. Somanath, Susan C. Fagan   +7 more
doaj   +1 more source

Simple and Efficient One-Pot Synthesis, Spectroscopic Characterization and Crystal Structure of Methyl 5-(4-Chlorobenzoyloxy)-1-phenyl-1H-pyrazole-3-carboxylate

Crystals, 2012
A facile one-pot synthesis of methyl 5-(4-chlorobenzoyloxy)-1-phenyl-1H-pyrazole-3-carboxylate (4) is described. The title compound was efficiently synthesized by the reaction of phenyl hydrazine, dimethyl acetylenedicarboxylate and 4-chlorobenzoyl ...
Imtiaz Khan, Jonathan M. White
doaj   +1 more source

Observation of a temperature dependent electrical resistance minimum above the magnetic ordering temperature in Gd$_2$PdSi$_3$ [PDF]

, 1998
Results on electrical resistivity, magnetoresistance, magnetic Results on electrical resistivity, magnetoresistance, magnetic susceptibility, heat capacity and Gd Mossbauer measurements on a Gd-based intermetallic compound, Gd$_{2}$PdSi$_{3}$ are ...
, , E. V Sampathkumaran, Elliot R. J., G Wortmann, Gratz E., M Strecker, Mallik R., Maple M. B., R Mallik   +9 more
core   +2 more sources

Novel epigallocatechin-3-gallate (EGCG) derivative as a new therapeutic strategy for reducing neuropathic pain after chronic constriction nerve injury in mice. [PDF]

PLoS ONE, 2015
Neuropathic pain is common in peripheral nerve injury and often fails to respond to ordinary medication. Here, we investigated whether the two novel epigallocatechin-3-gallate (EGCG) polyphenolic derivatives, compound 23 and 30, reduce the neuropathic ...
Xavier Xifró, Laura Vidal-Sancho, Pere Boadas-Vaello, Carlos Turrado, Jordi Alberch, Teresa Puig, Enrique Verdú   +6 more
doaj   +1 more source

Design and Synthesis of AMPK Activators and GDF15 Inducers

Molecules, 2023
Targeting growth differentiation factor 15 (GDF15) is a recent strategy for the treatment of obesity and type 2 diabetes mellitus (T2DM). Here, we designed, synthesized, and pharmacologically evaluated in vitro a novel series of AMPK activators to ...
Meijian Zhang, Andrea Bagán, Donna Martínez, Emma Barroso, Xavier Palomer, Santiago Vázquez, Carmen Escolano, Manuel Vázquez-Carrera   +7 more
doaj   +1 more source

O and Ne K absorption edge structures and interstellar abundance towards Cyg X-2 [PDF]

, 2002
We have studied the O and Ne absorption features in the X-ray spectrum of Cyg X-2 observed with the Chandra LETG. The O absorption edge is represented by the sum of three absorption-edge components within the limit of the energy resolution and the photon
Crovisier J., Kazuhisa Mitsuda, Koch-Miramond L., Predehl P., Ryuichi Fujimoto, Takashi Onaka, Verner D. A., Yoh Takei   +7 more
core   +2 more sources

Identification of valves and unions provided for fugitive emission monitoring according to EPA method 21

Revista Ingenio, 2016
This document presents the identification of valves and flanged unions of a plant for the processing and transformation of hydrocarbons. The identification was carried out in order to monitor the elements (flanged joints and valves) according to the ...
Edwin Espinel Blanco, Daniel Quintero, Lisneider Sanchez Ascanio   +2 more
doaj   +1 more source

2-(Arylamino)-6-(trifluoromethyl)nicotinic Acid Derivatives: New HIV-1 RT Dual Inhibitors Active on Viral Replication

Molecules, 2020
The persistence of the AIDS epidemic, and the life-long treatment required, indicate the constant need of novel HIV-1 inhibitors. In this scenario the HIV-1 Reverse Transcriptase (RT)-associated ribonuclease H (RNase H) function is a promising drug ...
Angela Corona, Valentina Onnis, Claudia Del Vecchio, Francesca Esposito, Yung-Chi Cheng, Enzo Tramontano   +5 more
doaj   +1 more source

Two New Koumine-Type Indole Alkaloids from Gelsemium elegans Benth.

Molecules, 2013
Two new indole alkaloids, 21-oxokoumine (1) and furanokoumine (2), were isolated from the roots of Gelsemium elegans Benth together with three known compounds.
Huanhuan Gao, Junsheng Guo, Xiaoli Hou, Mingxue Sun, Kai Xiao   +4 more
doaj   +1 more source

Effects of T- and P-odd weak nucleon interaction in nuclei: renormalizations due to residual strong interaction, matrix elements between compound states and their correlations with P-violating matrix elements

, 1994
Manifestations of P-,T-odd weak interaction between nucleons in nucleus are considered. Renormalization of this interaction due to residual strong interaction is studied.
A. Barroso, A. Bohr, A. Griffiths, A. Schafer, A.B. Migdal, C.M. Frankle, D. Boose, D. Cho, D.F. Zaretsky, D.F. Zaretsky, E. Blanke, E.M. Henley, F. Osterfeld, G. Adelberger, G. Bertsch, G.A. Lobov, G.E. Brown, I.B. Khriplovich, I.S. Towner, J. Speth, J.B. French, J.D. Bowman, J.F. Shriner, Jr., J.W. Negele, K. Goeke, L. Stodolsky, L.D. Landau, L.V. Inzhechik, L.V. Inzhechik, N. Auerbach, O. K. Vorov, O.P. Sushkov, O.P. Sushkov, O.P. Sushkov, P.A. Moldauer, P.K. Kabir, R. De Haro, S.G. Kadmensky, S.G. Kadmensky, S.K. Lamoreax, V. Klemt, V. V. Flambaum, V.A. Khodel, V.E. Bunakov, V.F. Dmitriev, V.M. Khatsymovsky, V.V. Flambaum, V.V. Flambaum, V.V. Flambaum, V.V. Flambaum, V.V. Flambaum, V.V. Flambaum, V.V. Flambaum, V.V. Flambaum, W.C. Haxton, Ya.B. Zeldovich   +55 more
core   +1 more source