Results 31 to 40 of about 2,189,580 (292)
Molecules, 2018 New amphiphilic 1,4-DHP derivative C12-Man-Q with remoted cationic moieties at positions 2 and 6 was synthesised to study DNA delivery activity. The results were compared with data obtained for cationic 1,4-DHP derivative D19, which is known to be the ...
Gunita Apsite +9 more
doaj +1 more source
Synthesis and biological evaluation of NAS-21 and NAS-91 analogues as potential inhibitors of the mycobacterial FAS-II dehydratase enzyme Rv0636 [PDF]
, 2008 The identification of potential new anti-tubercular cemotherapeutics is paramount due to the recent emergence of extensively drug-resistant strains of Mycobacterium tuberculosis (XDR-TB).Libraries of NAS-21 and NAS-91 analogues were synthesized and ...
Besra, Gurdyal S +2 more
core +2 more sources
陆军军医大学学报, 2022 Objective To observe the characteristics of mutation patterns in patients with compound EGFR mutations in the same exon and their resistance to EGFR TKIs, and to explore the clinical features and survival benefits among these non-small cell lung cancer ...
GUAN Xuhui +4 more
doaj +1 more source
, 2009 In this paper, we present a nonparametric method to estimate the heterogeneity of a random medium from the angular distribution of intensity transmitted through a slab of random material.
Bihan, Nicolas Le, Margerin, Ludovic
core +4 more sources
BMC Bioinformatics, 2018 Background Previous studies have suggested deep learning to be a highly effective approach for screening lead compounds for new drugs. Several deep learning models have been developed by addressing the use of various kinds of fingerprints and graph ...
Maya Hirohara +4 more
doaj +1 more source
Acta Pharmaceutica Sinica B, 2020 FTY720 and IMMH002, prodrugs for sphingosine-1-phosphate receptor 1 (S1P1) agonists, show inadequate and inconsistent levels of phosphorylation in humans compared to that in rats.
Qiong Xiao +8 more
doaj +1 more source
Doping of Ce in T-La2CuO4: Rigorous test for electron-hole symmetry for high-Tc superconductivity [PDF]
, 2006 We report that Ce doping was achieved in La2CuO4 with the K2NiF4 (T) structure for the first time by molecular beam epitaxy. A synthesis temperature of as low as ~ 630C and an appropriate substrate choice, i.e., (001)LaSrGaO4 (a \~ 3.843 A), enebled us ...
Naito, M., Tsukada, A., Yamamoto, H.
core +1 more source
Itinerant and local-moment magnetism in EuCr2As2 single crystals
, 2014 We report on the crystal structure, physical properties, and electronic structure calculations for the ternary pnictide compound EuCr2As2. X-ray diffraction studies confirmed that EuCr2As2 crystalizes in the ThCr2Si2-type tetragonal structure (space ...
Geibel, C. +3 more
core +1 more source
Pediatric Blood &Cancer, EarlyView.ABSTRACT Background Oral mucositis is a common and debilitating side effect of childhood cancer and stem cell transplant treatments. It affects the quality of life of children and young people (CYP) and places a strain on services. Photobiomodulation is recommended for oral mucositis prevention in international guidance but is poorly implemented in UK ...
Claudia Heggie +4 more
wiley +1 more source
AT2R Activation Improves Wound Healing in a Preclinical Mouse Model
BiomedicinesAbnormal skin healing resulting in chronic wounds or hypertrophic scarring remains a major healthcare burden. Here, the antifibrotic angiotensin II type 2 receptor (AT2R) signaling pathway was modulated to determine its impact on cutaneous wound healing.
Julia M. Harrison +4 more
doaj +1 more source