Results 261 to 270 of about 359,557 (359)

MOESM4 of Development of a high throughput drug screening assay to identify compounds that protect oligodendrocyte viability and differentiation under inflammatory conditions

, 2016
Elen Rosler, Karen Lariosa-Willingham, Jay S. Tung, Jason C. Dugas, Tassie L. Collins, Dmitri Leonoudakis   +5 more
openalex   +1 more source

Adaptor protein CIN85 potentiates the motility of osteosarcoma cells via the Akt/mTOR and MMP2‐COL3A1 axis

Molecular Oncology, EarlyView.
CIN85 is highly expressed in osteosarcoma, particularly in metastatic lesions. Its overexpression increases cell migration and Matrigel invasion, while silencing CIN85 suppresses these behaviors. Transcriptome analysis shows that CIN85 regulates MMP2, COL3A1, and Akt/mTOR signaling. Targeting these pathways reverses CIN85‐induced motility, highlighting
Iryna Horak, Iva Staniczková Zambo, Matěj Přikryl, Peter Múdry, Danica Zapletalová, Jarmila Navrátilová, Jiří Navrátil, Jan Šmarda, Liudmyla Drobot, Petr Beneš, Lucia Knopfová   +10 more
wiley   +1 more source

HEIDI: an experiment-management platform enabling high-throughput fragment and compound screening. [PDF]

Acta Crystallogr D Struct Biol
Metz A, Stegmann DP, Panepucci EH, Buehlmann S, Huang CY, McAuley KE, Wang M, Wojdyla JA, Sharpe ME, Smith KML.   +9 more
europepmc   +1 more source

Compound screening in cell-based models of tau inclusion formation: Comparison of primary neuron and HEK293 cell assays. [PDF]

J Biol Chem, 2020
Crowe A, Henderson MJ, Anderson J, Titus SA, Zakharov A, Simeonov A, Buist A, Delay C, Moechars D, Trojanowski JQ, Lee VM, Brunden KR.   +11 more
europepmc   +1 more source

Phytochemical screening of Indonesian brown rice (Oryza sativa L.) extracts compounds [PDF]

Christine Natalia Palis, Anna Safitri, Fatchiyah Fatchiyah   +2 more
openalex   +1 more source

Longitudinal circulating tumor DNA profiling in patients with advanced endometrial cancer using an off‐the‐shelf targeted NGS panel

Molecular Oncology, EarlyView.
Intratumour heterogeneity complicates precision management of advanced endometrial cancer. Circulating tumor DNA (ctDNA) offers a minimally invasive strategy to capture tumor evolution and therapeutic resistance. Here, we compare tumor‐agnostic NGS with tumor‐informed ddPCR, outlining their relative sensitivity, concordance, and clinical implications ...
Carlos Casas‐Arozamena, Karin Teien Lande, Eva Diaz, Ana Vilar, Juan Cueva, Efigenia Arias, Victoria Sampayo, Alicia Abalo, Nerea González, Eva Colás, Antonio Gil‐Moreno, Miguel Abal, Gema Moreno‐Bueno, Therese Sørlie, Kristina Lindemann, Laura Muinelo‐Romay   +15 more
wiley   +1 more source

Development and utility of a SARS-CoV-2 pseudovirus assay for compound screening and antibody neutralization assays. [PDF]

Heliyon
Manu AA, Owusu IA, Oyawoye FO, Languon S, Barikisu IA, Tawiah-Eshun S, Quaye O, Donkor KJ, Paemka L, Amegatcher GA, Denyoh PMD, Oduro-Mensah D, Awandare GA, Quashie PK.   +13 more
europepmc   +1 more source

Interaction of HS1BP3 with cortactin modulates TKS5 localisation, cell secretion and cancer malignancy

Molecular Oncology, EarlyView.
Here, we demonstrate that HS1BP3 interacts with Cortactin through a proline‐rich region (PRR3.1) and show that this interaction, and HS1BP3 itself, promote cancer cell proliferation and invasion. Inhibition of this interaction leads to build‐up of TKS5 in multivesicular endosomes and altered secretion of CD63 and CD9, providing an explanation for the ...
Arja Arnesen Løchen, Kristiane Søreng, Chiara Veroni, Laura Trachsel‐Moncho, Nagham Asp, Robin Gaupset, Lars Gustav Lyckander, Helene Knævelsrud, Lars Eftang, Anne Simonsen   +9 more
wiley   +1 more source

Correction: Mannose-B from Codonopsis pilosula modulates LAMB1 expression to enhance trophoblast function and alleviate subchorionic hematoma

Scientific Reports
Qian Sun, Yuan Gao, Kadirya Asan, Jing Ji, Jinjin Xu, Xiaoyan Wu, Jie Ren, Wen Feng, Mengwei Song, Sen Wang, Boyu Zhang, Ying Zhou, Conghui Han, Shun Liu, Wen Yang   +14 more
doaj   +1 more source

In Vitro Screening of the Antibacterial Activity and Identification of Bioactive Compounds From Plants against Selected Vibrio spp. Pathogens

, 2009
Anjana Sharma, Virendra Kumar Patel
openalex   +2 more sources