Results 41 to 50 of about 321,628 (199)
The ubiquitin‐proteasome system and autophagy as guardians of the cellular proteome
FEBS Letters, EarlyView.This Perspective covers the three principles governing the crosstalk between the ubiquitin‐proteasome system and autophagy in cellular proteostasis: (1) a shared ubiquitin code routing substrates via shuttle factors or autophagy receptors; (2) spatial compartmentalization into phase‐separated degradation hubs and organelle‐specific modules (exemplified
Ivan Dikic
wiley +1 more source
, 1994 Titre de la couv.Bibliogr.: p.
Centre d'éducation interculturelle et de compréhension internationale +1 more
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Molecular Oncology, EarlyView.Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson +9 more
wiley +1 more source
Concrete Swelling in Existing Dams
, 2011 Several chemical reactions are able to produce swelling of concrete for decades after its initial curing, a problem that affects a considerable number of concrete dams around the world.
Martinez Cutillas, Francisco J. +3 more
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COMP–PMEPA1 axis promotes epithelial‐to‐mesenchymal transition in breast cancer cells
Molecular Oncology, EarlyView.This study reveals that cartilage oligomeric matrix protein (COMP) promotes epithelial‐to‐mesenchymal transition (EMT) in breast cancer. We identify PMEPA1 (protein TMEPAI) as a novel COMP‐binding partner that mediates EMT via binding to the TSP domains of COMP, establishing the COMP–PMEPA1 axis as a key EMT driver in breast cancer.
Konstantinos S. Papadakos +6 more
wiley +1 more source
, 2020 Dans ce travail de Bachelor, nous nous intéressons à l'impact d'un enseignement explicite des stratégies de lecture-compréhension sur l'autonomie des élèves. Afin de mesurer une éventuelle influence, nous avons mené une séquence dans deux classes de 6ème
Geoffre, Thierry +2 more
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Molecular Oncology, EarlyView.Pre‐analytical handling critically determines liquid biopsy performance. This study defines practical best‐practice conditions for cell‐free DNA (cfDNA) and extracellular vesicle–derived DNA (evDNA), showing how processing time, storage conditions, tube type, and plasma input volume affect DNA integrity and mutation detection.
Jonas Dohmen +11 more
wiley +1 more source
Molecular Oncology, EarlyView.Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau +36 more
wiley +1 more source
Attitudes et compréhension de textes
, 1982 Dijk Teun Adrianus van. Attitudes et compréhension de textes. In: Bulletin de psychologie, tome 35 n°356, 1982. Langage et compréhension. pp.
Van Dijk, Teun A.
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L'image comme aide à la compréhension
, 1989 Godin Marc. L'image comme aide à la compréhension. In: Spirale. Revue de recherches en éducation, n°1, 1989. Les aides à la compréhension, sous la direction de Dominique Guy Brassart. pp.
Godin, Marc
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