Results 61 to 70 of about 1,083,136 (261)

Aspiration Pneumonitis Caused by Polyethylene Glycol-Electrolyte Solution Treated with Conservative Management

open access: yesCase Reports in Pediatrics, 2014
Polyethylene glycol (PEG) electrolyte solution, Golytely, is an osmotic laxative commonly used in preoperative bowel cleansing. In this case report, a 9-year-old boy developed aspiration pneumonitis following accidental infusion of PEG solution into his ...
Ricardo A. Mosquera   +2 more
doaj   +1 more source

To the problems of health management in the context of decentralization of power and spatial planning in the united territorial communities

open access: yesZaporožskij Medicinskij Žurnal, 2018
The purpose of the study is to determine the main factors that may adversely affect the spatial planning of the united territorial communities in the management of the healthcare industry. The reform of the administrative-territorial system of Ukraine
A. O. Yanchuk   +2 more
doaj   +1 more source

Establishment of a humanized patient‐derived xenograft mouse model of high‐grade serous ovarian cancer for preclinical evaluation of combination immunotherapy

open access: yesMolecular Oncology, EarlyView.
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric   +10 more
wiley   +1 more source

Revisiting Heinz-Lippman disease as a complication of chronic venous insufficiency

open access: yesJournal of Vascular Surgery Cases and Innovative Techniques
Chronic venous insufficiency with and without ulceration is a common complication of varicose veins. Heinz-Lippmann disease is a potentially underreported complication of chronic venous insufficiency that involves heterotopic ossification of the peri ...
Alisha Oropallo, MD, FACS   +3 more
doaj   +1 more source

E2A selectively regulates TGF‐β–induced apoptosis in KRAS‐mutant non‐small cell lung cancer

open access: yesMolecular Oncology, EarlyView.
Ability to induce apoptosis by TGF‐β is frequently lost in advanced lung adenocarcinoma despite intact TGF‐β signaling. We identify E2A as a mutant KRAS–dependent mediator of resistance to TGF‐β–induced apoptosis. TGF‐β induces E2A via SMAD3 in mutant KRAS cells, and E2A silencing restores apoptosis and enhances radiation response in cell lines ...
Sergei Chuikov   +3 more
wiley   +1 more source

Response to Chagas disease in Brazil: strategic milestones for achieving comprehensive health care. [PDF]

open access: yesRev Soc Bras Med Trop, 2022
Ramos AN   +12 more
europepmc   +1 more source

Longitudinal circulating tumor DNA profiling in patients with advanced endometrial cancer using an off‐the‐shelf targeted NGS panel

open access: yesMolecular Oncology, EarlyView.
Intratumour heterogeneity complicates precision management of advanced endometrial cancer. Circulating tumor DNA (ctDNA) offers a minimally invasive strategy to capture tumor evolution and therapeutic resistance. Here, we compare tumor‐agnostic NGS with tumor‐informed ddPCR, outlining their relative sensitivity, concordance, and clinical implications ...
Carlos Casas‐Arozamena   +15 more
wiley   +1 more source

Redesigning an Electronic Health Record in Argentina to Improve Comprehensive Health Care and Clinical Research. [PDF]

open access: yesStud Health Technol Inform, 2022
Giraldo L   +6 more
europepmc   +1 more source

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