Results 61 to 70 of about 2,741,781 (306)

Spatiotemporal and quantitative analyses of phosphoinositides – fluorescent probe—and mass spectrometry‐based approaches

open access: yesFEBS Letters, EarlyView.
Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho   +3 more
wiley   +1 more source

Building on our Success: Moving from Health Care Coverage to Improved Access and Comprehensive Well-Being for Illinois Children and Youth [PDF]

open access: yes, 2007
Building on our Success, a new report released by the Mid-America Institute on Poverty of Heartland Alliance, focuses on children's health in Illinois and documents the barriers in Illinois to achieving a healthy life in the areas of physical, mental and

core  

In situ molecular organization and heterogeneity of the Legionella Dot/Icm T4SS

open access: yesFEBS Letters, EarlyView.
We present a nearly complete in situ model of the Legionella Dot/Icm type IV secretion system, revealing its central secretion channel and identifying new components. Using cryo‐electron tomography with AI‐based modeling, our work highlights the structure, variability, and mechanism of this complex nanomachine, advancing understanding of bacterial ...
Przemysław Dutka   +11 more
wiley   +1 more source

The (Glg)ABCs of cyanobacteria: modelling of glycogen synthesis and functional divergence of glycogen synthases in Synechocystis sp. PCC 6803

open access: yesFEBS Letters, EarlyView.
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee   +3 more
wiley   +1 more source

Inclusion of mental health in primary health care: care strategy in the territory [PDF]

open access: yesRevista Brasileira de Enfermagem
Objective: To analyze the strategies, challenges and possibilities of the articulation between mental health and primary health care from the perspective of health managers.
Ândrea Cardoso de Souza   +2 more
doaj   +4 more sources

A national health information strategy for Malta [PDF]

open access: yes, 1993
In 1992 a national health information strategy was developed jointly by the Department of Health and the Information Systems Division. A detailed strategy study report was compiled, with recommendations for the development of a number of information ...
Agius Muscat, Hugo, Westwood, M.
core  

Tau acetylation at K331 has limited impact on tau pathology in vivo

open access: yesFEBS Letters, EarlyView.
We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto   +3 more
wiley   +1 more source

As repercussões do aleitamento materno exclusivo em crianças com baixo peso ao nascer

open access: yesSaúde em Debate
Objetivou-se investigar as repercussões do Aleitamento Materno (AM) exclusivo até o sexto mês de vida de crianças com baixo peso ao nascer. Trata-se de um estudo exploratório, com abordagem qualitativa, realizado em USF de João Pessoa.
Aline Micely Pontes   +4 more
doaj   +2 more sources

Agreement Between HEDIS Performance Assessments in the VA and Medicare Advantage: Is Quality in the Eye of the Beholder? [PDF]

open access: yes, 2016
Medicare Advantage (MA) plans and the Veterans Affairs (VA) health care system assess quality of care using standardized Healthcare Effectiveness Data and Information Set (HEDIS) performance measures. Little is known, however, about the relative accuracy
Charlton, Mary   +3 more
core  

Fetal Brain Tumor Harboring a Unique ROCK1::BRAF Fusion

open access: yes
Pediatric Blood &Cancer, EarlyView.
Marllon Cindra Sant'Ana   +8 more
wiley   +1 more source

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