Results 71 to 80 of about 2,741,781 (306)

AAA+ protein unfoldases—the Moirai of the proteome

FEBS Letters, EarlyView.
AAA+ unfoldases are essential molecular motors that power protein degradation and disaggregation. This review integrates recent cryo‐electron microscopy (cryo‐EM) structures and single‐molecule biophysical data to reconcile competing models of substrate translocation.
Stavros Azinas, Marta Carroni
wiley   +1 more source

The Evolution, Current Landscape, and Future Prospects of Oncolytic Virotherapy in Melanoma: Talimogene Laherparepvec and Beyond

Cells
Oncolytic viruses represent an emerging class of therapeutic agents that have the potential to transform the care of patients with melanoma. In this narrative review, we describe the evolution of oncolytic virus approaches.
John Smestad, John Rieth, Douglas Laux, Mohammed Milhem   +3 more
doaj   +1 more source

A Survey of Recent Research in Health Economics [PDF]

In this survey of recent research in health economics, I concentrate on studies that have appeared since 1971 or are in progress. The survey reflects in part my own research interests and biases and is not meant to be comprehensive.
Michael Grossman
core  

Infrared laser sampling of low volumes combined with shotgun lipidomics reveals lipid markers in palatine tonsil carcinoma

Molecular Oncology, EarlyView.
Nanosecond infrared laser (NIRL) low‐volume sampling combined with shotgun lipidomics uncovers distinct lipidome alterations in oropharyngeal squamous cell carcinoma (OPSCC) of the palatine tonsil. Several lipid species consistently differentiate tumor from healthy tissue, highlighting their potential as diagnostic markers.
Leonard Kerkhoff, Manuela Moritz, Dennis Eggert, Anna Worthmann, Joerg Heeren, Henrike Zech, Till S. Clauditz, Waldemar Wilczak, Hartmut Schlüter, Christian S. Betz, Arne Böttcher, Jan Hahn   +11 more
wiley   +1 more source

Matrix Support: interface between Specialty Dental Centers and primary oral health care in Brazil

BMC Health Services Research
Background Matrix Support (MS) is a strategy that can be used to improve integration between Primary Health Care (PHC) and other levels of care. Objective The aim of this study was to investigate the association between MS carried out in Brazilian Dental
Thaislaine Gonçalves Martins Santos, Livia Fernandes Probst, Rafaela da Silveira Pinto, Edilson José Zafalon, Alessandro Diogo De-Carli   +4 more
doaj   +1 more source

Aspiration Pneumonitis Caused by Polyethylene Glycol-Electrolyte Solution Treated with Conservative Management

Case Reports in Pediatrics, 2014
Polyethylene glycol (PEG) electrolyte solution, Golytely, is an osmotic laxative commonly used in preoperative bowel cleansing. In this case report, a 9-year-old boy developed aspiration pneumonitis following accidental infusion of PEG solution into his ...
Ricardo A. Mosquera, Mark McDonald, Cheryl Samuels   +2 more
doaj   +1 more source

OVC costing technical consultation meeting report [PDF]

, 2010
This item is archived in the repository for materials published for the USAID supported Orphans and Vulnerable Children Comprehensive Action Research Project (OVC-CARE) at the Boston University Center for Global Health and Development.The two day meeting
OVC‐CARE project
core  

The organisation and delivery of health improvement in general practice and primary care: a scoping study [PDF]

, 2015
Background This project examines the organisation and delivery of health improvement activities by and within general practice and the primary health-care team. The project was designed to examine who delivers these interventions, where they are located,
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core   +3 more sources

Targeted modulation of IGFL2‐AS1 reveals its translational potential in cervical adenocarcinoma

Molecular Oncology, EarlyView.
Cervical adenocarcinoma patients face worse outcomes than squamous cell carcinoma counterparts despite similar treatment. The identification of IGFL2‐AS1's differential expression provides a molecular basis for distinguishing these histotypes, paving the way for personalized therapies and improved survival in vulnerable populations globally.
Ricardo Cesar Cintra, Lucca Paolo Hsu Helmich, Daniel Rodrigues de Bastos, Laura Sichero, Patrícia Savio de Araujo‐Souza, Fabio Passetti, Luisa Lina Villa   +6 more
wiley   +1 more source

A integralidade na assistência à saúde da criança na visão dos cuidadores

Saúde em Debate
O artigo identifica o atributo integralidade e elementos do cuidado integral para resolução de problemas de saúde das crianças na percepção de seus cuidadores.
Rosane Meire Munhak da Silva, Cláudia Silveira Viera, Beatriz Rosana Gonçalves de Oliveira Toso, Eliane Tatsch Neves, Reinaldo Antônio da Silva-Sobrinho   +4 more
doaj   +1 more source