Results 71 to 80 of about 24,275 (291)
Interpreting the effects of DNA polymerase variants at the structural level
Molecular Oncology, EarlyView.Using MAVISp and molecular dynamics simulations, we analyzed over 60 000 missense variants in POLE and POLD1 from ClinVar, COSMIC, cBioPortal, and saturation mutagenesis. Identified mechanistic indicators, including stability, binding, and long‐range, enable structural interpretation, providing ACMG‐like evidence for possible reclassification of VUS ...
Matteo Arnaudi +7 more
wiley +1 more source
Multi-objective route planning for dangerous goods using compromise programming [PDF]
Compromise programming, Dangerous goods, GIS, Multi-objective route planning, C44, L92,
Rongrong Li, Yee Leung
core +1 more source
Neutrosophic Compromise Programming Approach for Multiobjective Nonlinear Transportation Problem with Supply and Demand Following the Exponential Distribution [PDF]
Operations Research and Decisions, 2022 Decision-making is a tedious and complex process. In the present competitive scenario, any incorrect decision may excessively harm an organization. Therefore, the parameters involved in the decision-making process should be looked into carefully as they ...
Ahmad Yusuf Adhami, Mohd Faizan, Anas M
doaj
Molecular Oncology, EarlyView.Single‐cell multi‐omics reveals epigenetic heterogeneity across therapy‐adaptive tumor states, including quiescent/dormant, drug‐tolerant persister, and EMT‐like phenotypes. By linking regulatory features with state‐associated biomarkers, these approaches inform biomarker‐guided therapeutic strategies for evolving tumors.
Hee Jung Kim +3 more
wiley +1 more source
Compromise Programming Untuk Pemilihan Portofolio [PDF]
, 2010 Portofolio merupakan gabungan atas sekumpulan asset yang dimiliki oleh investor. Dengan memiliki beberapa asset, resiko dapat dikurangi. Pada tugas akhir ini asset yang digunakan berupa saham, terdiri dari 5 saham perusahaan yaitu PT Gudang Garam ...
Ciptaningrum, Putri
core
Influence of aggregation and measurement scale on ranking a compromise alternative in AHP [PDF]
, 2011 Author's pre-print version dated 20. December 2009 deposited in Munich Personal RePEc Archive. Final version published by Palgrave Macmillan; available online at http:// www.palgrave-journals.com/Analytic Hierarchy Process (AHP) is one of the most ...
Kaplan, T. +4 more
core +2 more sources
A multi-criteria approach to the selection of the optimal investment alternative with software support [PDF]
Anali Ekonomskog fakulteta u Subotici, 2020 This paper proposes some possibilities of implementing information technology in investment management. The paper deals with the choice of the optimal investment alternative out of a series of alternatives compared, evaluated in the system of different ...
Nešić Zoran +2 more
doaj
FEBS Open Bio, EarlyView.Unique biological samples, such as site‐specific mutant proteins, are available only in limited quantities. Here, we present a polarization‐resolved transient infrared spectroscopy setup with referencing to improve signal‐to‐noise tailored towards tracing small signals. We provide an overview of characterizing the excitation conditions for polarization‐
Clark Zahn, Karsten Heyne
wiley +1 more source
Determination of Compromise Integer Strata Sample Sizes Using Goal Programming [PDF]
, 2004 This article deals with the determination of compromise integer strata sample sizes using goal programming in multivariate stratified sampling. Firstly, the problem of determining optimum integer strata sample sizes is formulated for the univariate case,
Semiz, Mustafa
core
A Compromise Programming Approach for Assessing Territorial Biophysical Suitability: A Case Study
LandLand-use fragmentation is an important issue for land management and rural development. For the last few decades, the relationship between mankind and land has become more dynamic though the traditional cadastral system has been slow in responding to the
António Xavier +2 more
doaj +1 more source