Results 71 to 80 of about 1,058,511 (255)

What Does Aspect−Oriented Programming Mean for Functional Programmers? [PDF]

open access: yes, 2009
Aspect-Oriented Programming (AOP) aims at modularising crosscutting concerns that show up in software. The success of AOP has been almost viral and nearly all areas in Software Engineering and Programming Languages have become "infected" by the AOP bug ...
Oliveira, BCDS   +7 more
core   +1 more source

A Compromise Programming Approach for Assessing Territorial Biophysical Suitability: A Case Study

open access: yesLand
Land-use fragmentation is an important issue for land management and rural development. For the last few decades, the relationship between mankind and land has become more dynamic though the traditional cadastral system has been slow in responding to the
António Xavier   +2 more
doaj   +1 more source

The VHL tumor suppressor at the crossroad of protein folding, aggregation, and cancer

open access: yesMolecular Oncology, EarlyView.
Mutations, environmental stress, and chaperone dysfunction can destabilize pVHL, promoting its conversion from the native folded state into amyloid‐like assemblies. This transition may contribute to protein storage, cell dormancy, survival, and drug resistance.
Lara Abad   +2 more
wiley   +1 more source

Hyperosmotic stress‐induced redistribution of pre‐mRNA cleavage factor I subunits is associated with shifts in alternative polyadenylation

open access: yesFEBS Open Bio, EarlyView.
Hyperosmotic stress triggers the relocation of the CFIm complex from the nucleus to the cytoplasm. This shift creates a nuclear ‘stoichiometric bottleneck’, limiting CFIm availability for mRNA processing. Consequently, specific mRNAs like NUDT21 and DICER1 undergo targeted 3′UTR shortening, demonstrating how spatial protein dynamics drive rapid ...
Hitomi Soumiya   +2 more
wiley   +1 more source

On the equivalence between compromise programming and the use of composite compromise metrics. [PDF]

open access: yes
This paper analyzes the relationship between Compromise Programming and a close relative called Composite Programming that is based on the use of composite metrics.
Carlos Romero, Francisco J. André
core  

The Hierarchical compromise programming

open access: yes
Hierarchical Compromise Programming, Compromise Programming, Hierarchy, Analytic Hierarchy Process, 90A05, 90B50, 90C31,
José Moreno-Jiménez, María Escobar
core   +1 more source

Treatment with KCL‐286, a first‐in‐class retinoic acid receptor‐β (RARβ) agonist, ameliorates neuronal DNA damage and inflammation in a mouse model of Alzheimer's disease

open access: yesFEBS Open Bio, EarlyView.
Repair of neuronal DNA damage in Alzheimer's disease by KCL‐286. (A) Amyloid‐β oligomers and plaques impair neuronal DNA repair pathways, leading to DNA double‐strand breaks and glial activation. (B) KCL‐286 activates RARβ/RXR signalling via retinoic acid response elements (RAREs), associated with increased BRCA1 expression, enhanced DNA repair and ...
Natasha Hill   +6 more
wiley   +1 more source

FUZZY LOGIC AND COMPROMISE PROGRAMMING IN PORTFOLIO MANAGEMENT [PDF]

open access: yes
The objective of this paper is to develop a portfolio optimization technique that is simple enough for an individual with little knowledge of economic theory to systematically determine his own optimized portfolio. A compromise programming approach and a
Featherstone, Allen M., Duval, Yann
core  

Optimization of Financial Portfolio by Using Nadir Compromising Programming [PDF]

open access: yesMuṭāli̒āt-i Mudīriyyat-i Ṣan̒atī, 2007
After introducing Markowitz mean-variance model, decision makers (DMs) and financial planners paid much attention to the matter of portfolio selection, so that DMs explain purposes and investment requirements in the frame of multi-objective mathematic ...
Maghsoud Amiri
doaj  

MagmaFlow: A desktop platform for artificial intelligence‐driven expression analysis

open access: yesFEBS Open Bio, EarlyView.
MagmaFlow is a free, no‐code platform for gene expression analysis. It generates interactive volcano plots, links genes to literature, pathways, and diseases, prioritizes candidates using millions of publications, identifies affected biological processes, builds network diagrams, and exports publication‐ready figures and reports for macOS and Windows ...
Carlos E. Buss   +7 more
wiley   +1 more source

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