Results 91 to 100 of about 8,231,669 (291)

Neutralization of the PTX3/CD44 axis suppresses TGF‐β1 signaling in kidney fibrosis

open access: yesFEBS Letters, EarlyView.
This study investigates how the PTX3/CD44 axis promotes kidney fibrosis by activating TGF‐β1 signaling. We demonstrate that the neutralizing antibody WHC‐001 effectively inhibits this pathway, suppressing myofibroblast activation and partial epithelial–mesenchymal transition (EMT).
Chao‐Chun Cheng   +8 more
wiley   +1 more source

The Relative Importance of Local Labour Market Conditions and Pupil Attainment on Post-Compulsory Schooling Decisions [PDF]

open access: yes
This paper assesses the relative importance of local labour market conditions and pupil educational attainment as primary determinants of the post-compulsory schooling decision.
Meschi, Elena   +2 more
core  

Research on Policy Diffusion of the Appointment System of Teachers in Compulsory Education in China

open access: yesKEDI Journal of Educational Policy
The appointment system of teachers in compulsory education is a strategic institutional arrangement for the employment of teachers in China. This study selected 1330 policy documents related to the appointment system of teachers in compulsory education ...
Jia Chao, Li Baoqiang
doaj   +1 more source

Careers guidance provisions and progression to post-16 education: An empirical analysis for Wales

open access: yesInternational Journal of Population Data Science, 2019
Careers guidance is widely regarded as important in supporting young people in making appropriate decisions following school. However, there is very little empirical evidence as to its effectiveness.
Rhys Davies, Suhaer Yunus, Katy Huxley
doaj   +1 more source

Inhibition of dipeptidyl peptidase 7 impairs lysophagy in LLOMe‐treated HepG2 cells

open access: yesFEBS Letters, EarlyView.
DPP7 inhibition delays ubiquitin‐dependent lysophagy by attenuating ubiquitin accumulation and the recruitment of SQSTM1 and LC3 to damaged lysosomes, resulting in delayed clearance of damaged lysosomes and impaired restoration of lysosomal homeostasis. Created using FigureLabs (Certificate ID: FL‐PUB‐20260922‐Z99XNX).
Na Yeon Park   +8 more
wiley   +1 more source

The Effect of Compulsory Schooling Laws on Teenage Marriage and Births in Turkey [PDF]

open access: yes
This paper estimates the impact of the extension of compulsory schooling in Turkey from 5 to 8 years on the marriage and fertility behavior of teenage women in Turkey using the 2008 Turkish Demographic and Health Survey.
Murat G. Kýrdar   +2 more
core   +2 more sources

DNA ligase LigE increases bacterial transformation with damaged extracellular DNA

open access: yesFEBS Letters, EarlyView.
The DNA ligase LigE from the naturally competent Gram‐negative bacterium Neisseria gonorrhoaea increases transformation with cut extracellular DNA. This process is ATP‐dependent and relies on the catalytic activity of LigE; it also requires that LigE contains an intact periplasmic localisation sequence, indicating that ligE functions in the periplasm ...
Jolyn Pan   +4 more
wiley   +1 more source

Does education improve health? A reexamination of the evidence from compulsory schooling laws [PDF]

open access: yes
This article analyzes the impact of compulsory schooling laws early in the twentieth century on long-term health. The author finds no compelling evidence for a causal link between education and health using this research design.
Bhashkar Mazumder
core  

Going viral − Virus‐targeting nanobodies for research, diagnostics and therapy

open access: yesFEBS Letters, EarlyView.
The increasing prevalence of viral diseases represents a major threat for global human health. Nanobodies, small binding fragments derived from camelid heavy‐chain antibodies, offer versatile tools for viral research, diagnostics, and antiviral therapy.
Domenic Ebert, Ulrich Rothbauer
wiley   +1 more source

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