Computational Biology: A New Frontier in Applied Biology [PDF]
All living things are related to one another [...]
Milan Toma, Riccardo Concu
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While women are generally underrepresented in STEM fields, there are noticeable differences between fields. For instance, the gender ratio in biology is more balanced than in computer science. We were interested in how this difference is reflected in the interdisciplinary field of computational/quantitative biology.
Kevin S. Bonham, Melanie I. Stefan
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SBSI:an extensible distributed software infrastructure for parameter estimation in systems biology [PDF]
Complex computational experiments in Systems Biology, such as fitting model parameters to experimental data, can be challenging to perform. Not only do they frequently require a high level of computational power, but the software needed to run the ...
Adams+21 more
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Correction: Atrial arrhythmogenicity of KCNJ2 mutations in short QT syndrome: Insights from virtual human atria. [PDF]
[This corrects the article DOI: 10.1371/journal.pcbi.1005593.].
PLOS Computational Biology Staff
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Correction: Ten Simple Rules for Taking Advantage of Git and GitHub. [PDF]
[This corrects the article DOI: 10.1371/journal.pcbi.1004947.].
PLOS Computational Biology Staff
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Development and validation of computational models of cellular interaction [PDF]
In this paper we take the view that computational models of biological systems should satisfy two conditions – they should be able to predict function at a systems biology level, and robust techniques of validation against biological models must be ...
Holcombe, W.M.L.+2 more
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Correction: Dose-response relationships for environmentally mediated infectious disease transmission models. [PDF]
[This corrects the article DOI: 10.1371/journal.pcbi.1005481.].
PLOS Computational Biology Staff
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All biology is computational biology
Here, I argue that computational thinking and techniques are so central to the quest of understanding life that today all biology is computational biology. Computational biology brings order into our understanding of life, it makes biological concepts rigorous and testable, and it provides a reference map that holds together individual insights.
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Correction: Depletion of the Chromatin Looping Proteins CTCF and Cohesin Causes Chromatin Compaction: Insight into Chromatin Folding by Polymer Modelling. [PDF]
[This corrects the article DOI: 10.1371/journal.pcbi.1003877.].
PLOS Computational Biology Staff
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Minimum Information About a Simulation Experiment (MIASE) [PDF]
Reproducibility of experiments is a basic requirement for science. Minimum Information (MI) guidelines have proved a helpful means of enabling reuse of existing work in modern biology. The Minimum Information Required in the Annotation of Models (MIRIAM)
Hucka, Michael, Waltemath, Dagmar
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