Results 91 to 100 of about 1,427,211 (329)
Functional impact of multi-omic interactions in lung cancer
Frontiers in GeneticsLung tumors are a leading cause of cancer-related death worldwide. Lung cancers are highly heterogeneous on their phenotypes, both at the cellular and molecular levels.
Miguel Ángel Díaz-Campos +5 more
doaj +1 more source
Molecular Oncology, EarlyView.To integrate multiple transcriptomics data with severe batch effects for identifying MB subtypes, we developed a novel and accurate computational method named RaMBat, which leveraged subtype‐specific gene expression ranking information instead of absolute gene expression levels to address batch effects of diverse data sources.
Mengtao Sun, Jieqiong Wang, Shibiao Wan
wiley +1 more source
On the Complexity of Target Set Selection in Simple Geometric Networks [PDF]
Discrete Mathematics & Theoretical Computer ScienceWe study the following model of disease spread in a social network. At first, all individuals are either infected or healthy. Next, in discrete rounds, the disease spreads in the network from infected to healthy individuals such that a healthy individual
Michal Dvořák +2 more
doaj +1 more source
Computational Complexity of the Interleaving Distance
, 2018 The interleaving distance is arguably the most prominent distance measure in topological data analysis. In this paper, we provide bounds on the computational complexity of determining the interleaving distance in several settings.
Bjerkevik, Håvard Bakke +1 more
core
Rethinking plastic waste: innovations in enzymatic breakdown of oil‐based polyesters and bioplastics
FEBS Open Bio, EarlyView.Plastic pollution remains a critical environmental challenge, and current mechanical and chemical recycling methods are insufficient to achieve a fully circular economy. This review highlights recent breakthroughs in the enzymatic depolymerization of both oil‐derived polyesters and bioplastics, including high‐throughput protein engineering, de novo ...
Elena Rosini +2 more
wiley +1 more source
Computer science, computer, computational complexity
Chebyshevskii sbornik, 2021 Vladimir Nikolaevich Chubarikov +3 more
openaire +2 more sources
Frontiers in Genetics, 2019 Analysis of gene regulatory networks allows the identification of master transcriptional factors that control specific groups of genes. In this work, we inferred a gene regulatory network from a large dataset of breast cancer samples to identify the ...
Diana Tapia-Carrillo +5 more
doaj +1 more source
Interplay between RNA‐protein interactions and RNA structures in gene regulation
FEBS Open Bio, EarlyView.Methodological advances in mapping transcriptome‐wide RNA‐protein interactions and RNA structures have started to uncover the potential of RNP conformations in gene regulation. Competing RNA–RNA, RNA‐protein and protein–protein interactions shape the compaction and function of RNPs throughout their lifetime and may provide novel therapeutic targets in ...
Jenni Rapakko +2 more
wiley +1 more source
The computational complexity of convex bodies
, 2006 We discuss how well a given convex body B in a real d-dimensional vector space V can be approximated by a set X for which the membership question: ``given an x in V, does x belong to X?'' can be answered efficiently (in time polynomial in d).
Barvinok, Alexander, Veomett, Ellen
core +1 more source
The Computational Complexity of the Traveling Salesman Problem [PDF]
, 2011 In this note, we show that the Traveling Salesman Problem cannot be solved in polynomial-time on a classical computer.Comment: 1 page, made a minor ...
Feinstein, Craig Alan
core +2 more sources