Results 41 to 50 of about 1,395,371 (292)
FEBS Letters, EarlyView.In this study, we present the structure of AcrIE8.1, a previously uncharacterized anti‐CRISPR protein that inhibits the type I‐E CRISPR‐Cas system. Through a combination of structural and biochemical analyses, we demonstrate that AcrIE8.1 directly binds to the Cas11 subunit of the Cascade complex to inhibit the CRISPR‐Cas system.
Young Woo Kang, Hyun Ho Park
wiley +1 more source
Data Integration Challenges for Machine Learning in Precision Medicine
Frontiers in Medicine, 2022 A main goal of Precision Medicine is that of incorporating and integrating the vast corpora on different databases about the molecular and environmental origins of disease, into analytic frameworks, allowing the development of individualized, context ...
Mireya Martínez-García +2 more
doaj +1 more source
The IQ‐compete assay for measuring mitochondrial protein import efficiencies in living yeast cells
FEBS Letters, EarlyView.The efficiency of mitochondrial protein import depends on the properties of the newly synthesized precursor proteins. The Import and de‐Quenching Competition (IQ‐compete) assay is a novel method to monitor the import efficiency of different proteins by fluorescence in living yeast cells.
Yasmin Hoffman +3 more
wiley +1 more source
Fourier spectra of measures associated with algorithmically random Brownian motion [PDF]
Logical Methods in Computer Science, 2014 In this paper we study the behaviour at infinity of the Fourier transform of Radon measures supported by the images of fractal sets under an algorithmically random Brownian motion.
Willem Louw Fouché +2 more
doaj +1 more source
Reducing Computational Complexity of Quantum Correlations
, 2015 We address the issue of reducing the resource required to compute information-theoretic quantum correlation measures like quantum discord and quantum work deficit in two qubits and higher dimensional systems.
A. S. Holevo +12 more
core +1 more source
Molecular bases of circadian magnesium rhythms across eukaryotes
FEBS Letters, EarlyView.Circadian rhythms in intracellular [Mg2+] exist across eukaryotic kingdoms. Central roles for Mg2+ in metabolism suggest that Mg2+ rhythms could regulate daily cellular energy and metabolism. In this Perspective paper, we propose that ancestral prokaryotic transport proteins could be responsible for mediating Mg2+ rhythms and posit a feedback model ...
Helen K. Feord, Gerben van Ooijen
wiley +1 more source
Frontiers in ImmunologyBreast cancer, characterized by its complexity and diversity, presents significant challenges in understanding its underlying biology. In this study, we employed gene co-expression network analysis to investigate the gene composition and functional ...
Tadeo Enrique Velazquez-Caldelas +3 more
doaj +1 more source
Eliminating the Effect of Rating Bias on Reputation Systems
Complexity, 2018 The ongoing rapid development of the e-commercial and interest-base websites makes it more pressing to evaluate objects’ accurate quality before recommendation.
Leilei Wu +4 more
doaj +1 more source
Computational Creativity and Aesthetics with Algorithmic Information Theory
Entropy, 2021 We build an analysis based on the Algorithmic Information Theory of computational creativity and extend it to revisit computational aesthetics, thereby, improving on the existing efforts of its formulation.
Tiasa Mondol, Daniel G. Brown
doaj +1 more source
On computational complexity of Set Automata
, 2017 We consider a computational model which is known as set automata. The set automata are one-way finite automata with an additional storage---the set. There are two kinds of set automata---the deterministic and the nondeterministic ones.
Rubtsov, Alexander A. +1 more
core +1 more source