Results 61 to 70 of about 1,395,371 (292)
MathematicsWe investigate a nonlinear integral equation derived through moment approximation from the individual-based representation of spatial logistic dynamics. The equation describes how the densities of pairs of individuals represented by points in continuous ...
Mikhail Nikolaev +2 more
doaj +1 more source
Epistemic virtues, metavirtues, and computational complexity [PDF]
, 2003 I argue that considerations about computational complexity show that all finite agents need characteristics like those that have been called epistemic virtues.
Morton, Professor Adam
core
A bioinformatics screen identifies TCF19 as an aggressiveness‐sustaining gene in prostate cancer
Molecular Oncology, EarlyView.Gene expression meta‐analysis in multiple prostate cancer patient cohorts identifies Transcription factor 19 (TCF19) as an aggressiveness‐sustaining gene with prognostic potential. TCF19 is a gene repressed by androgen signaling that sustains core cancer‐related processes such as vascular permeability or tumor growth and metastasis.
Amaia Ercilla +15 more
wiley +1 more source
On computational complexity of Siegel Julia sets
, 2005 It has been previously shown by two of the authors that some polynomial Julia sets are algorithmically impossible to draw with arbitrary magnification.
Binder, I., Braverman, M., Yampolsky, M.
core +1 more source
A synthetic benzoxazine dimer derivative targets c‐Myc to inhibit colorectal cancer progression
Molecular Oncology, EarlyView.Benzoxazine dimer derivatives bind to the bHLH‐LZ region of c‐Myc, disrupting c‐Myc/MAX complexes, which are evaluated from SAR analysis. This increases ubiquitination and reduces cellular c‐Myc. Impairing DNA repair mechanisms is shown through proteomic analysis.
Nicharat Sriratanasak +8 more
wiley +1 more source
Injecting Observers into Computational Complexity
PhilosophiesWe characterize computer science as an interplay between two modes of reasoning: the Aristotelian (procedural) method and the Platonic (declarative) approach.
Edgar Graham Daylight
doaj +1 more source
Aggressive prostate cancer is associated with pericyte dysfunction
Molecular Oncology, EarlyView.Tumor‐produced TGF‐β drives pericyte dysfunction in prostate cancer. This dysfunction is characterized by downregulation of some canonical pericyte markers (i.e., DES, CSPG4, and ACTA2) while maintaining the expression of others (i.e., PDGFRB, NOTCH3, and RGS5).
Anabel Martinez‐Romero +11 more
wiley +1 more source
Probabilistic Recursion Theory and Implicit Computational Complexity [PDF]
Scientific Annals of Computer Science, 2014 We show that probabilistic computable functions, i.e., those func- tions outputting distributions and computed by probabilistic Turing machines, can be characterized by a natural generalization of Church and Kleene’s partial recursive functions.
U. Dal Lago, S. Zuppiroli, M. Gabbrielli
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Special Issue “Quantum computation complexity theory and quantum network theory” (Preface) [PDF]
, 2021 Junde Wu
openalex +1 more source
Molecular Oncology, EarlyView.Clinical trials on PARP inhibitors in urothelial carcinoma (UC) showed limited efficacy and a lack of predictive biomarkers. We propose SLFN5, SLFN11, and OAS1 as UC‐specific response predictors. We suggest Talazoparib as the better PARP inhibitor for UC than Olaparib.
Jutta Schmitz +15 more
wiley +1 more source