Results 81 to 90 of about 1,437,104 (331)
On the Computational Complexity of Determining Value [PDF]
, 2021 Tiasa Mondol
openalex +1 more source
Effective therapeutic targeting of CTNNB1‐mutant hepatoblastoma with WNTinib
Molecular Oncology, EarlyView.WNTinib, a Wnt/CTNNB1 inhibitor, was tested in hepatoblastoma (HB) experimental models. It delayed tumor growth and improved survival in CTNNB1‐mutant in vivo models. In organoids, WNTinib outperformed cisplatin and showed enhanced efficacy in combination therapy, supporting its potential as a targeted treatment for CTNNB1‐mutated HB.
Ugne Balaseviciute +17 more
wiley +1 more source
Communication complexity of entanglement assisted multi-party computation [PDF]
, 2023 Ruoyu Meng, Aditya Ramamoorthy
openalex +1 more source
The Computational Complexity of the Traveling Salesman Problem [PDF]
, 2011 In this note, we show that the Traveling Salesman Problem cannot be solved in polynomial-time on a classical computer.Comment: 1 page, made a minor ...
Feinstein, Craig Alan
core +2 more sources
LDAcoop: Integrating non‐linear population dynamics into the analysis of clonogenic growth in vitro
Molecular Oncology, EarlyView.Limiting dilution assays (LDAs) quantify clonogenic growth by seeding serial dilutions of cells and scoring wells for colony formation. The fraction of negative wells is plotted against cells seeded and analyzed using the non‐linear modeling of LDAcoop.
Nikko Brix +13 more
wiley +1 more source
Depth lower bounds in Stabbing Planes for combinatorial principles [PDF]
Logical Methods in Computer ScienceStabbing Planes (also known as Branch and Cut) is a proof system introduced very recently which, informally speaking, extends the DPLL method by branching on integer linear inequalities instead of single variables.
Stefan Dantchev +3 more
doaj +1 more source
Computational complexity of the landscape II - Cosmological considerations
, 2018 We propose a new approach for multiverse analysis based on computational complexity, which leads to a new family of "computational" measure factors. By defining a cosmology as a space-time containing a vacuum with specified properties (for example small ...
Denef, Frederik +3 more
core +1 more source
Molecular Oncology, EarlyView.We show that the majority of the 18 analyzed recurrent cancer‐associated ERBB4 mutations are transforming. The most potent mutations are activating, co‐operate with other ERBB receptors, and are sensitive to pan‐ERBB inhibitors. Activating ERBB4 mutations also promote therapy resistance in EGFR‐mutant lung cancer.
Veera K. Ojala +15 more
wiley +1 more source
Low Complexity V-BLAST MIMO-OFDM Detector by Successive Iterations Reduction
, 2015 V-BLAST detection method suffers large computational complexity due to its successive detection of symbols. In this paper, we propose a modified V-BLAST algorithm to decrease the computational complexity by reducing the number of detection iterations ...
Abuelenin, Sherif +3 more
core +2 more sources
Peroxidasin enables melanoma immune escape by inhibiting natural killer cell cytotoxicity
Molecular Oncology, EarlyView.Peroxidasin (PXDN) is secreted by melanoma cells and binds the NK cell receptor NKG2D, thereby suppressing NK cell activation and cytotoxicity. PXDN depletion restores NKG2D signaling and enables effective NK cell–mediated melanoma killing. These findings identify PXDN as a previously unrecognized immune evasion factor and a potential target to improve
Hsu‐Min Sung +17 more
wiley +1 more source