Results 81 to 90 of about 5,239,116 (369)
Frontiers in ImmunologyBreast cancer, characterized by its complexity and diversity, presents significant challenges in understanding its underlying biology. In this study, we employed gene co-expression network analysis to investigate the gene composition and functional ...
Tadeo Enrique Velazquez-Caldelas +3 more
doaj +1 more source
Eliminating the Effect of Rating Bias on Reputation Systems
Complexity, 2018 The ongoing rapid development of the e-commercial and interest-base websites makes it more pressing to evaluate objects’ accurate quality before recommendation.
Leilei Wu +4 more
doaj +1 more source
Computational Creativity and Aesthetics with Algorithmic Information Theory
Entropy, 2021 We build an analysis based on the Algorithmic Information Theory of computational creativity and extend it to revisit computational aesthetics, thereby, improving on the existing efforts of its formulation.
Tiasa Mondol, Daniel G. Brown
doaj +1 more source
FEBS Letters, EarlyView.Antimicrobial resistance (AMR) is of huge importance, resulting in over 1 million deaths each year. Here, we describe how a new drug, enmetazobactam, designed to help fight resistant bacterial diseases, inhibits a key enzyme (GES‐1) responsible for AMR. Our data show it is a more potent inhibitor than the related tazobactam, with high‐level computation
Michael Beer +10 more
wiley +1 more source
FEBS Letters, EarlyView.Single‐cell RNA sequencing reveals an opposite role of SLPI in basal tumors based on metastatic spread, along with shared activation of specific regulons in cancer cells and mature luminal lactocytes, as well as downregulation of MALAT1 and NEAT1 in the latter.
Pietro Ancona +4 more
wiley +1 more source
Computational models of hemostasis: Degrees of complexity
Applications in Engineering Science, 2022 The history of studies on blood clotting goes back to the emergence of civilized society itself. The foundations of the modern scientific study of hemostasis are based on the discovery of erythrocytes in blood in 1674 and, later, that of platelets in ...
M. Anand +2 more
doaj +1 more source
Revealing the structure of land plant photosystem II: the journey from negative‐stain EM to cryo‐EM
FEBS Letters, EarlyView.Advances in cryo‐EM have revealed the detailed structure of Photosystem II, a key protein complex driving photosynthesis. This review traces the journey from early low‐resolution images to high‐resolution models, highlighting how these discoveries deepen our understanding of light harvesting and energy conversion in plants.
Roman Kouřil
wiley +1 more source
Epistemic virtues, metavirtues, and computational complexity [PDF]
, 2003 I argue that considerations about computational complexity show that all finite agents need characteristics like those that have been called epistemic virtues.
Morton, Professor Adam
core
Comorbidity patterns in cardiovascular diseases: the role of life-stage and socioeconomic status
Frontiers in Cardiovascular MedicineCardiovascular diseases stand as a prominent global cause of mortality, their intricate origins often entwined with comorbidities and multimorbid conditions.
Héctor A. Cruz-Ávila +5 more
doaj +1 more source
FEBS Letters, EarlyView.Angiotensin II (AngII), a neuropeptide, interacts with amyloid‐β (Aβ), a key player in Alzheimer's disease. This study reveals that AngII reduces Aβ aggregation and membrane disruption in vitro. Biophysical assays and molecular modeling suggest AngII binds disordered Aβ forms, potentially modulating early amyloidogenic events and contributing to ...
Mohsen Habibnia +5 more
wiley +1 more source